Aptamer-target interaction descriptor
Aptamer-target interaction information
Interaction ID: 1006
Aptamer sequence: GGCACTTGTTTGCTCGAACGATGGTTTGTGCTTTTGTGTT
Target unique ID: Other-31
| Aptamer ID | Aptamer descriptor | Target chemistry | Target name | Affinity | Binding Conditions/Buffer | PubMed ID |
|---|---|---|---|---|---|---|
| Apta_913 | C4 | Other | Rituximab | 86.7 nM | 20 mM Tris pH 7.6, 100 mM NaCl, 2 mM MgCl2, 5 mM KCl, 1 mM CaCl2, 0.02% v/v Tween 20 | 33151990 |
Structure information of aptamer
| Aptamer Sequence: | GGCACTTGTTTGCTCGAACGATGGTTTGTGCTTTTGTGTT |
| The optimal secondary structure in dot-bracket notation: | .((((......((.(((((....))))).))....)))). |
| The centroid secondary structure in dot-bracket notation: | .((((......((.(((((....))))).))....)))). |
The MFE structure
The Centroid structure
The mountain plot representation
Aptamer information
| Type | Detail | Type | Detail |
|---|---|---|---|
| Aptamer ID | Apta_913 | Description | C4 |
| Aptamer chemistry | DNA | Length | 40 nt |
| GC content | 45.0% | Molecular weight | 12,351.90 Da |
| Molarity of 1 μg/μl solution | 80.96 μM | Number of G-quadruplexes | No QGRS found |
| G-Score | N/A | Function | Target detection |
| Sequence | GGCACTTGTTTGCTCGAACGATGGTTTGTGCTTTTGTGTT | ||
| Applications | Detection of rituximab | ||
Target information
| Type | Detail | Type | Detail |
|---|---|---|---|
| Target ID | Other-31 | Name | Rituximab |
Activity data
 |
Interaction ID | 1006 |
| Target type | Other | |
| Target unique ID | Other-31 | |
| Activity | 86.7 nM | |
| Binding Conditions/Buffer | 20 mM Tris pH 7.6, 100 mM NaCl, 2 mM MgCl2, 5 mM KCl, 1 mM CaCl2, 0.02% v/v Tween 20 |
|
| Assay | Titration of aptamers for heat-treated rituximab binding using ELASA |
|
| PubMed ID | 33151990 |
Similar aptamers
| Aptamer ID | Aptamer chemistry | Sequence | Similarity |
|---|---|---|---|
| Apta_482 | DNA | AGCAAGGTTTGGTGTTGGTTGGTTGCTGGTTTTGGTTTC | |
| Apta_882 | DNA | AATAGTCTGGTTCGGTGCTTGGTGCGATGTGTTAGTCAGACTCTTGTGTG | |
| Apta_914 | DNA | CGCTCCGTTTACTCGGTCTGCTATTGGCTTGCCTTTGTTT | |
| Apta_1236 | DNA | GGACTGTTGTGGTATTATTTTTGGTTGTGC | |
| Apta_1237 | DNA | GGGGTTGTGTGGGGAGTTTGTCCTGTTGTG | |
| Apta_1238 | DNA | GGTTTTGTGTTTGTGTTTTGTGGTTGTTGT | |
| Apta_543 | DNA | GGCACGTGTTGTCTCTCTGTGTCTCGTGCC | |
| Apta_564 | DNA | GGGGACTGTTGTGGTATTATTTTTGGTTGTGCAGT | |
| Apta_682 | DNA | CCTTGTAGATCGGGTGTGGTTTGGCGTAGG | |
| Apta_1204 | DNA | GGCACGATGTGGCTACATCGATCGCGGTACTGGTG | |
| Apta_1205 | DNA | GGCAGGTGGTGTTGGTTGGTTGTGCGTGGAGTTGG | |
| Apta_1204 | DNA | GGCACGATGTGGCTACATCGATCGCGGTACTGGTG | |
| Apta_1246 | DNA | GGAGATGTATGAGCGGGTGTTTGTGTTTGC | |
| Apta_1247 | DNA | GGTGGTTGCTGTTGTTTGTGGTTGGTGTGC | |
| Apta_238 | DNA | CACACATTCCCGTCCTCGATACGTCTAGGCTTAGTGCCACTTGCTTAATC | |
| Apta_223 | DNA | CATTGAGATAGCTAGTTGTAGCTGCGTCATAGGCTGGGTTGGGTCTAGTGGTTGGGTGTG | |
| Apta_498 | DNA | GAACTCATTGGCTGGAGGCGGCAGTACCGCTTGAGTT | |
| Apta_542 | DNA | GCACGTGTTGTCTCTCTGTGTCTCGTGC | |
| Apta_858 | DNA | GGCTTCAGGTTGGTCTGGTTGGGTTTGGCTCCTGTGTACG | |
| Apta_1239 | DNA | GGTGGATGGGGATGCTTTGTTAGTTTGTGC |
DEV TOOL
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