Aptamer-target interaction descriptor
Aptamer-target interaction information
Interaction ID: 238
Aptamer sequence: AGCAGCACAGAGGTCAGATGTGAAACATAGCATATTTACTTATGTCGCCTTGCCGGTTCCTATGCGTGCTACCGTGAA
Target unique ID: Other-52
Aptamer ID Aptamer descriptor Target chemistry Target name Affinity Binding Conditions/Buffer PubMed ID
Apta_233 4.4.12 Other Ig E 23 nM PBS and 1 mM MgCl2 (pH 8.0) 15362896
Structure information of aptamer
Aptamer Sequence: AGCAGCACAGAGGTCAGATGTGAAACATAGCATATTTACTTATGTCGCCTTGCCGGTTCCTATGCGTGCTACCGTGAA
The optimal secondary structure in dot-bracket notation: .((((((((.((((.(((((((........))))))))))).))).))..)))((((.............))))....
The centroid secondary structure in dot-bracket notation: .((((((((.((((.(((((((........))))))))))).))).))..)))((((.............))))....
The MFE structure
The Centroid structure
The mountain plot representation
Aptamer information
Type Detail Type Detail
Aptamer ID Apta_233 Description 4.4.12
Aptamer chemistry DNA Length 78 nt
GC content 47.4% Molecular weight 24,290.36 Da
Molarity of 1 μg/μl solution 41.17 μM Number of G-quadruplexes No QGRS found
G-Score N/A Function Targeted binding
Sequence AGCAGCACAGAGGTCAGATGTGAAACATAGCATATTTACTTATGTCGCCTTGCCGGTTCCTATGCGTGCTACCGTGAA
Applications Binding to target human IgG
Target information
Type Detail Type Detail
Target ID Other-52 Name Ig E
Activity data

No relevant experimental diagram

 Interaction ID 238
Target type Other
Target unique ID Other-52
Activity 23 nM
Binding Conditions/Buffer

PBS and 1 mM MgCl2 (pH 8.0)
Assay

N/A
PubMed ID 15362896
Similar aptamers
Aptamer ID Aptamer chemistry Sequence Similarity
Apta_104 DNA AGCAGCACAGAGGTCAGATGCAAACCACAGCCTGAGTGGTTAGCGTATGTCATTTACGGACCTATGCGTGCTACCGTGAA 77.50%
Apta_104 DNA AGCAGCACAGAGGTCAGATGCAAACCACAGCCTGAGTGGTTAGCGTATGTCATTTACGGACCTATGCGTGCTACCGTGAA 77.50%
Apta_228 DNA AGCAGCACAGAGGTCAGATGCGGCGCGGGGTCTTTTACAAATAGTTGTCCTAGCCACGCCTATGCGTGCTACCGTGAA 74.36%
Apta_175 DNA AGCAGCACAGAGGTCAGATGAGGACTGTCGATAAGTATAATGGCAAGTAGCTCGATACATCCTATGCGTGCTACCGTGAA 73.75%
Apta_234 DNA AGCAGCACAGAGGTCAGATGAAATTTTGCACTTACTTGACGTTTCCTCGATAGCCACAAGCCTATGCGTGCTACCGTGAA 73.75%
Apta_232 DNA AGCAGCACAGAGGTCAGATGCTATGAGCAGATCCGATAGAAAGTTAATGCCCTAGAACATCCTATGCGTGCTACCGTGAA 72.50%
Apta_236 DNA AGCAGCACAGAGGTCAGATGAGATGGTTGACCGGTTGATGTGATTAAGGAGACGTCGATTCCTATGCGTGCTACCGTGAA 72.50%
Apta_101 DNA AGCAGCACAGAGGTCAGATGTGTTAGGCTGGGACACGTATTACACTTACCGTAAATATTTCCTATGCGTGCTACCGTGAA 71.25%
Apta_107 DNA AGCAGCACAGAGGTCAGATGTTCATTTCAGTTGACCGATAGCATTGAGCAATGATCTATTCCTATGCGTGCTACCGTGAA 71.25%
Apta_110 DNA AGCAGCACAGAGGTCAGATGGTTAGGAAGGTGAATAGGTACGACTGCAGGTCTATCGCAGCCTATGCGTGCTACCGTGAA 71.25%
Apta_101 DNA AGCAGCACAGAGGTCAGATGTGTTAGGCTGGGACACGTATTACACTTACCGTAAATATTTCCTATGCGTGCTACCGTGAA 71.25%
Apta_107 DNA AGCAGCACAGAGGTCAGATGTTCATTTCAGTTGACCGATAGCATTGAGCAATGATCTATTCCTATGCGTGCTACCGTGAA 71.25%
Apta_110 DNA AGCAGCACAGAGGTCAGATGGTTAGGAAGGTGAATAGGTACGACTGCAGGTCTATCGCAGCCTATGCGTGCTACCGTGAA 71.25%
Apta_173 DNA AGCAGCACAGAGGTCAGATGGCAGGTTTCGACGTACAATGCTATGGAGGCTTTATGATCGCCTATGCGTGCTACCGTGAA 71.25%
Apta_174 DNA AGCAGCACAGAGGTCAGATGTCGGTCTTGTGTATACATACCCGTGTGTTTTCATCTCAGGCCTATGCGTGCTACCGTGAA 71.25%
Apta_235 DNA AGCAGCACAGAGGTCAGATGTGGTTCGATGCTGCAAGGTGTTGTCATTTGGCATATGTTACCTATGCGTGCTACCGTGAA 71.25%
Apta_698 DNA AGCAGCACAGAGGTCAGATGCACTCGGACCCCATTCTCCTTCCATCCCTCATCCGTCCACCCTATGCGTGCTACCGTGAA 71.25%
Apta_61 DNA AGCAGCACAGAGGTCAGATGGCAGGTAAGCAGGCGGCTCACAAAACCATTCGCATGCGGCCCTATGCGTGCTACCGTGAA 70.00%
Apta_100 DNA AGCAGCACAGAGGTCAGATGATTCAAGGGTAACACATCCAGGGGAACGGAATTGCAGCCCCCTATGCGTGCTACCGTGAA 70.00%
Apta_105 DNA AGCAGCACAGAGGTCAGATGATGCTCTAGGCGAAAGACTTGGCGTAGAACGACGGGAGGCCCTATGCGTGCTACCGTGAA 70.00%

ABOUT

AptaDB is an online database we developed to integrate comprehensive information about aptamer.
The detail of this database is described here:

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