Aptamer-target interaction descriptor
Aptamer-target interaction information
Interaction ID: 1004
Aptamer sequence: GGCCATTGTGGACTTCTTTGGGTAATTCAGGGGCTCGATT
Target unique ID: Other-31
| Aptamer ID | Aptamer descriptor | Target chemistry | Target name | Affinity | Binding Conditions/Buffer | PubMed ID |
|---|---|---|---|---|---|---|
| Apta_911 | C7 | Other | Rituximab | 8.8 nM | 20 mM Tris pH 7.6, 100 mM NaCl, 2 mM MgCl2, 5 mM KCl, 1 mM CaCl2, 0.02% v/v Tween 20 | 33151990 |
Structure information of aptamer
| Aptamer Sequence: | GGCCATTGTGGACTTCTTTGGGTAATTCAGGGGCTCGATT |
| The optimal secondary structure in dot-bracket notation: | ((((.(((...((((....))))....))).))))..... |
| The centroid secondary structure in dot-bracket notation: | ((((.(((...(((......)))....))).))))..... |
The MFE structure
The Centroid structure
The mountain plot representation
Aptamer information
| Type | Detail | Type | Detail |
|---|---|---|---|
| Aptamer ID | Apta_911 | Description | C7 |
| Aptamer chemistry | DNA | Length | 40 nt |
| GC content | 50.0% | Molecular weight | 12,379.93 Da |
| Molarity of 1 μg/μl solution | 80.78 μM | Number of G-quadruplexes | No QGRS found |
| G-Score | N/A | Function | Target detection |
| Sequence | GGCCATTGTGGACTTCTTTGGGTAATTCAGGGGCTCGATT | ||
| Applications | Detection of rituximab | ||
Target information
| Type | Detail | Type | Detail |
|---|---|---|---|
| Target ID | Other-31 | Name | Rituximab |
Activity data
 |
Interaction ID | 1004 |
| Target type | Other | |
| Target unique ID | Other-31 | |
| Activity | 8.8 nM | |
| Binding Conditions/Buffer | 20 mM Tris pH 7.6, 100 mM NaCl, 2 mM MgCl2, 5 mM KCl, 1 mM CaCl2, 0.02% v/v Tween 20 |
|
| Assay | Titration of aptamers for heat-treated rituximab binding using ELASA |
|
| PubMed ID | 33151990 |
Similar aptamers
| Aptamer ID | Aptamer chemistry | Sequence | Similarity |
|---|---|---|---|
| Apta_443 | DNA | GGCCATGACGATGTCGTTACGTAGATGCAGAGACTCCTAA | |
| Apta_916 | DNA | GGCGTATGCAGTTTTGTAGGGTTATCAAGGCTTGACGATT | |
| Apta_1092 | DNA | CCCATGGTAGGTATTGCTTGGTAGGGATAGTGGGCTTGATG | |
| Apta_438 | DNA | AGCCATGACGATGTCGTTACGTAGATGCAGAGACTCCTAA | |
| Apta_438 | DNA | AGCCATGACGATGTCGTTACGTAGATGCAGAGACTCCTAA | |
| Apta_444 | DNA | AGCCATTACGATGTCGTTACGTAGATGCAGAGACTCCTAA | |
| Apta_1091 | DNA | CCATGGTAGGTATTGCTTGGTAGGGATAGTGGGCTTGATG | |
| Apta_596 | DNA | GGTGGCTGTTGGTCGAGGCTTATTAGTGTAGTCAATGGAGGCAGGCGACG | |
| Apta_69 | DNA | AGCGAGTAGGTTGGTGTGGTTGGGGCTCGCT | |
| Apta_71 | DNA | GGCGAGTAGGTTGGTGTGGTTGGGGCTCGCC | |
| Apta_72 | DNA | AGTCAGTAGGTTGGTGTGGTTGGGGCTGACT | |
| Apta_392 | DNA | GGATAGTTCGGTGGCTGTTCAGGGTCTCCTCCT | |
| Apta_445 | DNA | AGCCATGACGATGTCGTTACGTAGATGTAGAGACTCCTAA | |
| Apta_446 | DNA | AGCCATGACGATGTCGTTACGTAGATGCATAGACTCCTAA | |
| Apta_497 | DNA | GTTCGATTGGATTGTGCCGGAAGTGCTGGCTCGAAC | |
| Apta_1254 | DNA | GGCAGTGTGGGCGAATCTATGCGTACCGTTCGATATCGTG | |
| Apta_1255 | DNA | GGCGCATGATCATTCGGTGGGTAAGGTGGTGGTAACGTTG | |
| Apta_654 | DNA | GCACACCGATGGCGGTCCTGTTTTACGGTAGCTTATATGCAGGGGGTGTGCGTG | |
| Apta_47 | DNA | GACCTAGCAGTGGACATGTGGCAGGGTGAAGTGGCATCGTC | |
| Apta_391 | DNA | ACCGTGGAGGATAGTTCGGTGGCTGTTCAGGGTCTCCTCCACGGT |
DEV TOOL
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