MetaADEDB 2.0 @ LMMD
Bendroflumethiazide
(HDWIHXWEUNVBIY-UHFFFAOYSA-N)
Structure
SMILES
O=S1(=O)NC(Cc2ccccc2)Nc2c1cc(c(c2)C(F)(F)F)S(=O)(=O)N
Type(s)
Approved
ATC code(s)
C03AA01; C03AB01; C03EA13; G01AE10
Molecular Formula:
C15H14F3N3O4S2
Molecular Weight:
421.415
Log P:
4.9541
Hydrogen Bond Acceptor:
7
Hydrogen Bond Donor:
3
TPSA:
135.12
CAS Number(s):
73-48-3
Synonym(s)
1.
Bendroflumethiazide
2.
Bendrofluazide
3.
Aprinox
4.
Benzide
5.
Benzide-M
6.
Berkozide
7.
Centyl
8.
Esberizid
9.
Naturetin
10.
Naturine
11.
Neo-NaClex
12.
Pluryl
13.
Urizid
14.
Benzide M
15.
Neo NaClex
External Link(s)
MeSHD001539
PubChem Compound2315
ChEBI3013
CHEMBLCHEMBL1684
DrugBankDB00436
DrugCentral305
IUPHAR/BPS Guide to PHARMACOLOGY7122
KEGGcpd:C07758
dr:D00650
Therapeutic Target DatabaseD02PAH
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Abdominal AbscessOFFSIDES
2AcidosisOFFSIDES
3Anal abscessOFFSIDES
4AngioedemaOFFSIDES
5AnorexiaSIDER
6Anti-erythropoietin antibody positiveOFFSIDES
7ApathyOFFSIDES
8ArteriosclerosisOFFSIDES
9AstheniaSIDER
10AsthmaOFFSIDES
11AuraOFFSIDES
12Benign Prostatic HyperplasiaOFFSIDES
13Blood pressure immeasurableOFFSIDES
14Blood sodiumOFFSIDES
15Blurred visionOFFSIDES
16Bulbar palsyOFFSIDES
17Burning sensationOFFSIDES
18C-reactive protein abnormalOFFSIDES
19Chemotherapeutic drug level increasedOFFSIDES
20CholangiolitisOFFSIDES
21Chronic left ventricular failureOFFSIDES
22ConfabulationOFFSIDES
23Conjunctival depositOFFSIDES
24ConstipationSIDER
25Depressed moodOFFSIDES
26DermatitisSIDER
27Diabetes MellitusSIDER
28DiplopiaOFFSIDES
29DiverticulumOFFSIDES
30DizzinessSIDER
31DrowsinessOFFSIDES
32EndophthalmitisOFFSIDES
33Epigastric discomfortSIDER
34EpilepsyOFFSIDES
35Erectile dysfunction6115999CTD
SIDER
36Erosive gastritisOFFSIDES
37ExcoriationOFFSIDES
38Eyelid DiseasesOFFSIDES
39Fatigue17452686CTD
OFFSIDES
40Floppy iris syndromeOFFSIDES
41Gastric irritationSIDER
42GastroenteritisOFFSIDES
43GoutCanada Vigilance: 16115999CTD
SIDER
Canada Vigilance
44Hallucinations, mixedOFFSIDES
45Heart failure3709557CTD
46Helicobacter pylori identification test positiveOFFSIDES
47HemiparesisOFFSIDES
48Hepatic EncephalopathySIDER
49Hyperaldosteronism20009770CTD
50Hypercalcemia17344567CTD
51HyperventilationOFFSIDES
52HypocalciuriaSIDER
53Hypokalemia

View details

326460
417199
594295
2209135
2570476
2729315
6134137
6487484
17452686
 		CTD
54Hyponatremia7331904
17452686		CTD
55HypotensionSIDER
56HypotensiveSIDER
57Increased upper airway secretionOFFSIDES
58Infusion site mobility decreasedOFFSIDES
59Infusion site painOFFSIDES
60Injection site infectionOFFSIDES
61Intention tremorOFFSIDES
62Intestinal PerforationOFFSIDES
63Iron OverloadOFFSIDES
64Left Ventricular HypertrophyOFFSIDES
65LethargyOFFSIDES
66Leukocytoclastic vasculitisSIDER
67LymphedemaOFFSIDES
68LymphomaOFFSIDES
69Malignant HypertensionOFFSIDES
70Mental impairmentOFFSIDES
71Middle insomniaOFFSIDES
72Musculoskeletal chest painOFFSIDES
73Musculoskeletal stiffnessOFFSIDES
74NauseaSIDER
75Nephritis, Interstitial6604293CTD
76Neutropenic sepsisOFFSIDES
77PancreatitisSIDER
78ParanoiaOFFSIDES
79ParotitisOFFSIDES
80Pelvic abscessOFFSIDES
81Pneumocystis jiroveci pneumoniaOFFSIDES
82PolyuriaSIDER
83Potassium imbalanceSIDER
84Procedural hypertensionOFFSIDES
85PsoriasisOFFSIDES
86PurpuraCanada Vigilance: 1Canada Vigilance
SIDER
87Rectal dischargeOFFSIDES
88Scedosporium infectionOFFSIDES
89Syncope17452686CTD
90TetanyOFFSIDES
91ThirstSIDER
92ThrombocytopeniaCanada Vigilance: 1Canada Vigilance
SIDER
93Urine output increasedSIDER
94Uterine PolypOFFSIDES
95Vascular purpuraSIDER
96VomitingSIDER
97Weight Gain6339121
6346849		CTD
98Wound ComplicationOFFSIDES
99colonoscopyOFFSIDES
100effusionOFFSIDES
101prostatitisOFFSIDES
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