Aptamer-target interaction descriptor
Aptamer-target interaction information
Interaction ID: 978
Aptamer sequence: GGCGACCCCCGGGCTACCAGACAATGTACGCAGCAAGAGTGACGGTCGTACCTCGGAGTC
Target unique ID: Other-25
Aptamer ID Aptamer descriptor Target chemistry Target name Affinity Binding Conditions/Buffer PubMed ID
Apta_888 Aptamer clone19 Other Escherichia coli (ETEC) K88 44 nM 20 mmol/L HEPES, 1 mmol/L MgCl2, 1 mmol/L CaCl2 and 120 mmol/L KCl 21627466
Structure information of aptamer
Aptamer Sequence: GGCGACCCCCGGGCTACCAGACAATGTACGCAGCAAGAGTGACGGTCGTACCTCGGAGTC
The optimal secondary structure in dot-bracket notation: ...(((..(((((.(((..(((..(((.(((.......)))))))))))).))))).)))
The centroid secondary structure in dot-bracket notation: ...(((..(((((.(((..(((..(((.(((.......)))))))))))).))))).)))
The MFE structure
The Centroid structure
The mountain plot representation
Aptamer information
Type Detail Type Detail
Aptamer ID Apta_888 Description Aptamer clone19
Aptamer chemistry DNA Length 60 nt
GC content 63.3% Molecular weight 18,505.85 Da
Molarity of 1 μg/μl solution 54.04 μM Number of G-quadruplexes No QGRS found
G-Score N/A Function Target detection
Sequence GGCGACCCCCGGGCTACCAGACAATGTACGCAGCAAGAGTGACGGTCGTACCTCGGAGTC
Applications Detection of Escherichia coli K88
Target information
Type Detail Type Detail
Target ID Other-25 Name Escherichia coli (ETEC) K88
Activity data

No relevant experimental diagram

 Interaction ID 978
Target type Other
Target unique ID Other-25
Activity 44 nM
Binding Conditions/Buffer

20 mmol/L HEPES, 1 mmol/L MgCl2, 1 mmol/L CaCl2 and 120 mmol/L KCl
Assay

N/A
PubMed ID 21627466
Similar aptamers
Aptamer ID Aptamer chemistry Sequence Similarity
Apta_684 DNA GGCGGACCAAGGGGACACCACAGATGAATGTACAGTACCATGTTACTGCGCCCGTAGGTG 58.33%
Apta_996 DNA ATAGGAGTCGACCGACCAGACAACCCTACGCGACCAACCAGATGACCTACGTGCGTCTACATCTAGACTC 57.14%
Apta_755 DNA GGGGAGGGAGACACAGTCATGGAGCAGTTATTAGGGTGTACCGGGTGTAGT 56.67%
Apta_1001 DNA ATAGGAGTCGACCGACCAGACAACCCTACGCGTACCAACCAGATGACCTACGTGCGTCTACATCTAGACTC 56.34%
Apta_1001 DNA ATAGGAGTCGACCGACCAGACAACCCTACGCGTACCAACCAGATGACCTACGTGCGTCTACATCTAGACTC 56.34%
Apta_1009 DNA ATAGGAGTCGACCGACCAGACCAACCCTACGCTCGTACCAACCAGATGACCTACGTGGCGTCTACATCTAGACTC 56.00%
Apta_998 DNA ATAGGAGTCGACCGACCAGACCAACCCTACGCGTACCAACCAGATGACCTACGTGCGTCTACATCTAGACTC 55.56%
Apta_728 DNA CGACCCGGCACAAACCCAGAACCATATACACGATCATTAGTCTCCTGGGCCG 55.00%
Apta_735 DNA AGGCCCCCAGGCTCGGTGGATGCAAACACATGACTATGGGCCCGT 55.00%
Apta_1010 DNA ATAGGAGTCGACCGACCAGACCGACCCTCGTCGTACCAACTGATGACCTAGTGGCGTCTACATCTAGACTC 54.93%
Apta_999 DNA ATAGGAGTCGACCGACCAGAGGACCCCGCTATCTAATTTATAGGCAATAAGTGCGTCTACATCTAGACTC 54.29%
Apta_1104 DNA TACGACTCACTATAGGGATCCCCCCGAGTGAAGAGCAGGACAGCGGGACAGCGTCGAATTCCCTTTAGTGAGGGTT 53.95%
Apta_839 DNA TGAGCCCAAGCCCTGGTATGAGCCCACGGAACACTGGTCGCGCCCACTGGTTTCTATATTGGCAGGTCTACTTTGGGATC 53.75%
Apta_840 DNA TGAGCCCAAGCCCTGGTATGCGGATAACGAGGTATTCACGACTGGTCGTCAGGTATGGTTGGCAGGTCTACTTTGGGATC 53.75%
Apta_47 DNA GACCTAGCAGTGGACATGTGGCAGGGTGAAGTGGCATCGTC 53.33%
Apta_155 RNA GACCCAGGGCCGGGACGCAAAGCAGCCAAAACAGACGGCCCCAGUCAGGGAGUU 53.33%
Apta_662 DNA GGCGCCAAACAGGACCACCATGACAATTACCCATACCACCTCATTATGCCCCATCTCCGC 53.33%
Apta_1172 DNA GACGCCACTGACTACCCCAGTATCTCTTCAACGCGTATTGAAGTCAGTCGGTCGTCA 53.33%
Apta_1220 DNA TGGCGACAAGAAGACGTACAAACACGCACCAGGCCGGAGTGGAGTATTCTGAGGTCGG 53.33%
Apta_1227 DNA CACACCAAACACACAAGTGGACCCTGACGCATGGATAGGGTGACGGTATACGCGGGCATG 53.33%

ABOUT

AptaDB is an online database we developed to integrate comprehensive information about aptamer.
The detail of this database is described here:

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