Aptamer-target interaction descriptor
Aptamer-target interaction information
| Aptamer ID | Aptamer descriptor | Target chemistry | Target name | Affinity | Binding Conditions/Buffer | PubMed ID |
|---|---|---|---|---|---|---|
| Apta_1160 | SC Primer | Protein | LYAM1_HUMAN | N/A | N/A | 25826688 |
Structure information of aptamer
| Aptamer Sequence: | TTCAGTATCCCACGGGTGGAATCA |
| The optimal secondary structure in dot-bracket notation: | .....(((((...)))))...... |
| The centroid secondary structure in dot-bracket notation: | .....(((((...)))))...... |
The MFE structure
The Centroid structure
The mountain plot representation
Aptamer information
| Type | Detail | Type | Detail |
|---|---|---|---|
| Aptamer ID | Apta_1160 | Description | SC Primer |
| Aptamer chemistry | DNA | Length | 24 nt |
| GC content | 50.0% | Molecular weight | 7,352.76 Da |
| Molarity of 1 μg/μl solution | 136.00 μM | Number of G-quadruplexes | No QGRS found |
| G-Score | N/A | Function | Targeted therapy |
| Sequence | TTCAGTATCCCACGGGTGGAATCA | ||
| Applications | Inhibit L-selectin | ||
Target information
| Type | Detail | Type | Detail |
|---|---|---|---|
| Uniprot ID | P14151 | Protein name | L-selectin (CD62 antigen-like family member L) (Leukocyte adhesion molecule 1) (LAM-1) (Leukocyte surface antigen Leu-8) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (Lymph node homing receptor) (TQ1) (gp90-MEL) (CD antigen CD62L) |
| Gene name(s) | SELL LNHR LYAM1 | Organism | L-selectin (CD62 antigen-like family member L) (Leukocyte adhesion molecule 1) (LAM-1) (Leukocyte surface antigen Leu-8) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (Lymph node homing receptor) (TQ1) (gp90-MEL) (CD antigen CD62L) |
| Status | reviewed in uniprot database | Length | 372 |
| Mass | 42,187 | Activity regulation | N/A |
| Involvement in disease | N/A | Catalytic activity | N/A |
| PDB ID(s) | 2LGF;3CFW;5VC1; |
 |
Function | Calcium-dependent lectin that mediates cell adhesion by binding to glycoproteins on neighboring cells. |
Activity data
|
No relevant experimental diagram |
Interaction ID | 1220 |
| Target type | Protein | |
| Target unique ID | P14151 | |
| Activity | N/A | |
| Binding Conditions/Buffer | N/A |
|
| Assay | N/A |
|
| PubMed ID | 25826688 |
Similar aptamers
| Aptamer ID | Aptamer chemistry | Sequence | Similarity |
|---|---|---|---|
| Apta_345 | DNA | ACAGTAACCGCGTGAGGTCGA | |
| Apta_208 | DNA | AGGAAGGGGTGGAAT | |
| Apta_577 | DNA | ACTTCAGTGAGTTGTCCCACGGTCGGCGAGTCGGTGGTAG | |
| Apta_323 | DNA | GGCTATAGCACATGGGTAAAACGAC | |
| Apta_325 | DNA | TACTGCATGCACACCACTTCAACTA | |
| Apta_323 | DNA | GGCTATAGCACATGGGTAAAACGAC | |
| Apta_323 | DNA | GGCTATAGCACATGGGTAAAACGAC | |
| Apta_325 | DNA | TACTGCATGCACACCACTTCAACTA | |
| Apta_505 | DNA | CTAAAGTGCCTCACGCTGTTAACTC | |
| Apta_66 | DNA | TACCGTGGTAGGGAAGGTTGGAGTGTA | |
| Apta_423 | DNA | TGGGAGCTGATGTCGCATGGGTTTTGATCACATGA | |
| Apta_779 | DNA | TACGGGCTGGATCCACTGTTACGGCGTGTATCCGCTATCAA | |
| Apta_201 | DNA | CTGAGATCTCGGAAT | |
| Apta_371 | RNA | GGCAGACCAUACGGGAGAGAAACUUGCC | |
| Apta_372 | RNA | GACCAUACGGGAGAGAAACU | |
| Apta_491 | DNA | TTGGGGTCTGCTCGGGATTGCGGAGAACGTGAATCT | |
| Apta_676 | DNA | TCAGTCCCGATCAGGTGTGGGTGGCATTGG | |
| Apta_946 | DNA | TACCGGGTAATATGCACACATGCTGATAGCAAGCAATGCA | |
| Apta_1024 | DNA | GTCCAGGGTTCCAAGGTGCTTCGTGGAC | |
| Apta_1149 | DNA | ATCATGGTGGGTATCGGCACTCGTTGGTTGAT |
DEV TOOL
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