AptaDB: Result

Interaction ID: 1010

Aptamer sequence: TCGATTTCCTTAGTTGTCTTCCTTAGTGAG

Target unique ID: Other-32

Aptamer ID	Aptamer descriptor	Target chemistry	Target name	Affinity	Binding Conditions/Buffer	PubMed ID
Apta_917	ABA	Other	anti-FLAG M2 antibody	80 nM	4% glycerol, 1 mM MgCL2, 1 mM DTT, 50 mM NaCl, 10 mM Tris-HCl, pH 7.5, r.t.	22013507

Aptamer Sequence:	TCGATTTCCTTAGTTGTCTTCCTTAGTGAG
The optimal secondary structure in dot-bracket notation:	.(((((.....)))))..............
The centroid secondary structure in dot-bracket notation:	..............................

The MFE structure

The Centroid structure

The mountain plot representation

Type	Detail	Type	Detail
Aptamer ID	Apta_917	Description	ABA
Aptamer chemistry	DNA	Length	30 nt
GC content	40.0%	Molecular weight	9,159.89 Da
Molarity of 1 μg/μl solution	109.17 μM	Number of G-quadruplexes	No QGRS found
G-Score	N/A	Function	Targeted therapy
Sequence	TCGATTTCCTTAGTTGTCTTCCTTAGTGAG
Applications	Blocks the Function of the Anti-FLAG M2 Antibody

Type	Detail	Type	Detail
Target ID	Other-32	Name	anti-FLAG M2 antibody

No relevant experimental diagram	Interaction ID	1010
	Target type	Other
	Target unique ID	Other-32
	Activity	80 nM
	Binding Conditions/Buffer	4% glycerol, 1 mM MgCL2, 1 mM DTT, 50 mM NaCl, 10 mM Tris-HCl, pH 7.5, r.t.
	Assay	N/A
	PubMed ID	22013507

Aptamer ID	Aptamer chemistry	Sequence	Similarity
Apta_822	DNA	TAGCCCTTCAACATAGTAATATCTCTGCATTCTGTGATG	58.97%
Apta_604	DNA	TCCTGACCTTAGCCTATGTTTTCTCTACCGGCTATGTTAC	57.50%
Apta_163	DNA	GCGCATGACCATTGATGTCTGCACCATCAGAGGCAGAG	55.26%
Apta_1024	DNA	GTCCAGGGTTCCAAGGTGCTTCGTGGAC	53.33%
Apta_1282	DNA	TCCTCTCACACATCTTATCCCCTAGGG	53.33%
Apta_338	DNA	GGGCGCGTTCTTCGTGGTTACTTTTAGTCCCG	53.12%
Apta_1036	DNA	ATACCAGTCTATTCAATTGGGCCCGTCCGTATGGTGGG	52.63%
Apta_165	DNA	TGGACGAACTGCCCTCAGCTACTTTCATGTTGCTGACGCA	52.50%
Apta_914	DNA	CGCTCCGTTTACTCGGTCTGCTATTGGCTTGCCTTTGTTT	52.50%
Apta_963	DNA	TGGCGCTGCCCCTAGTCTCCGGCTGATAGCTGCTTCTTGG	52.50%
Apta_1286	DNA	CTATACGTATTCTAACTTGTTACGTATTGGTCTCTTATTG	52.50%
Apta_144	DNA	GGTGCGGTTCGTGCGGTTGTAGTACTCGTGGCCGATAGAGGTAG	52.27%
Apta_407	DNA	GTGAATTGCGTTGAATTATGTTTTTTCAGTCATCACT	51.35%
Apta_41	DNA	CGGTCGCTCCGTGTGGCTTGGGTTGGGTGTGGCAGTGAC	51.28%
Apta_159	DNA	GCGTGCAGCATGACCACCGATGTCACACTTAATGAGAAT	51.28%
Apta_644	DNA	TCAATCTAACCATGCATGCAGTTTAGGCAGGATTCGTTATCGCAA	51.11%
Apta_820	DNA	TCCCACGATCTCATTAGTCTGTGGATAAGCGTGGGACGTCTATGA	51.11%
Apta_57	DNA	GCGGGTCGGTTGCTCGCTTCGCCCGATCGGTCTAAGGGTG	50.00%
Apta_146	DNA	GGTGCGGTTCGTGCGGTTGTAGTACTCGTGGCCG	50.00%
Apta_216	DNA	TGGTTGGTTTTTGGTTTTTTTTTTTGGTTT	50.00%

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