Aptamer-target interaction descriptor
Aptamer-target interaction information
| Aptamer ID | Aptamer descriptor | Target chemistry | Target name | Affinity | Binding Conditions/Buffer | PubMed ID |
|---|---|---|---|---|---|---|
| Apta_757 | AS1411 | Cell | vaccinia virus–infected and–uninfected lung cancer A549 cells | 10 CFU/mL | A549 PBS solutions or whole blood | 29920439 |
Structure information of aptamer
| Aptamer Sequence: | GGTGGTGGTGGTTGTGGTGGTGG |
| The optimal secondary structure in dot-bracket notation: | ....................... |
| The centroid secondary structure in dot-bracket notation: | ....................... |
The MFE structure
The Centroid structure
The mountain plot representation
Aptamer information
| Type | Detail | Type | Detail |
|---|---|---|---|
| Aptamer ID | Apta_757 | Description | AS1411 |
| Aptamer chemistry | DNA | Length | 23 nt |
| GC content | 65.2% | Molecular weight | 7,309.67 Da |
| Molarity of 1 μg/μl solution | 136.81 μM | Number of G-quadruplexes | 2 |
| G-Score | 21 | Function | Aptasensor |
| Sequence | GGTGGTGGTGGTTGTGGTGGTGG | ||
| Applications | Biomedical researches | ||
Target information
| Type | Detail | Type | Detail |
|---|---|---|---|
| ATCC ID | CRM-CCL-185 | Cell name | vaccinia virus-infected and-uninfected lung cancer A549 cells |
| Category | Human cells | Organism | Homo sapiens, human |
| Product type | Certified reference material | Cell type | epithelial cell |
| Morphology | epithelial | Tissue | Lung |
| Disease | Carcinoma | Product format | Frozen |
| Antigen expression | N/A | Genes expressed | N/A |
| Cell description | N/A |
|
|
| Application(s) | Assay development | ||
Activity data
 |
Interaction ID | 840 |
| Target type | Cell | |
| Target unique ID | CRM-CCL-185 | |
| Activity | 10 CFU/mL | |
| Binding Conditions/Buffer | A549 PBS solutions or whole blood |
|
| Assay | Cells detection on AS1411-PGO-I-ISE in PBS and blood samples |
|
| PubMed ID | 29920439 |
Similar aptamers
| Aptamer ID | Aptamer chemistry | Sequence | Similarity |
|---|---|---|---|
| Apta_350 | DNA | GGTGGTGGTGGTTGTGGTGGTGGTGG | |
| Apta_1247 | DNA | GGTGGTTGCTGTTGTTTGTGGTTGGTGTGC | |
| Apta_10 | DNA | GGGGGGGGTGGCTGGGCGGGGTGGG | |
| Apta_25 | DNA | TGTGGGGGTGGTTGGGCGGGGCTGC | |
| Apta_389 | DNA | GCCTGTGGTGTTGGGGCGGGTGCG | |
| Apta_679 | DNA | CAGGTGGCAGATCGGGTGTGGGTGGCCTGG | |
| Apta_1205 | DNA | GGCAGGTGGTGTTGGTTGGTTGTGCGTGGAGTTGG | |
| Apta_1193 | DNA | GGGTTGGAGGTGGAGGGGAGTTGAGG | |
| Apta_211 | DNA | GGTTGGTGTGGTTGG | |
| Apta_11 | DNA | AGAGGGGGGGGTCGGGGTGGGTCGC | |
| Apta_12 | DNA | TGAGGGGGTGGGTGGGACGGGTTGG | |
| Apta_13 | DNA | AGGGGGGGGGGAGGGGTCGGGGTGG | |
| Apta_14 | DNA | AGCGGGGGGGGCTGGGCTGGGTGGG | |
| Apta_20 | DNA | AGAGGGGGGGGTGGGGGTGGCCTGC | |
| Apta_22 | DNA | TGTGGGGGTGGACTGGGTGGGTACC | |
| Apta_806 | DNA | GGTTGGATGTAAGGTTGGAGGGGGG | |
| Apta_124 | DNA | GGTGGTGGGGGGGGTTGGTAGGGTGTCTTC | |
| Apta_673 | DNA | GCAGTCCTAGATCGGGTGTGGCTGGCTTGG | |
| Apta_1085 | DNA | TGGGGTGGTGGTGTGGGTGGGGGTTTGTTC | |
| Apta_1237 | DNA | GGGGTTGTGTGGGGAGTTTGTCCTGTTGTG |
DEV TOOL
 |
 |
 |
 |