Aptamer-target interaction descriptor
Aptamer-target interaction information
Interaction ID: 1009
Aptamer sequence: GGCGTATGCAGTTTTGTAGGGTTATCAAGGCTTGACGATT
Target unique ID: Other-31
| Aptamer ID | Aptamer descriptor | Target chemistry | Target name | Affinity | Binding Conditions/Buffer | PubMed ID |
|---|---|---|---|---|---|---|
| Apta_916 | C57 | Other | Rituximab | 82.4 nM | 20 mM Tris pH 7.6, 100 mM NaCl, 2 mM MgCl2, 5 mM KCl, 1 mM CaCl2, 0.02% v/v Tween 20 | 33151990 |
Structure information of aptamer
| Aptamer Sequence: | GGCGTATGCAGTTTTGTAGGGTTATCAAGGCTTGACGATT |
| The optimal secondary structure in dot-bracket notation: | ..(((....(((((((.........)))))))..)))... |
| The centroid secondary structure in dot-bracket notation: | ..(((....(((((((.........)))))))..)))... |
The MFE structure
The Centroid structure
The mountain plot representation
Aptamer information
| Type | Detail | Type | Detail |
|---|---|---|---|
| Aptamer ID | Apta_916 | Description | C57 |
| Aptamer chemistry | DNA | Length | 40 nt |
| GC content | 45.0% | Molecular weight | 12,427.98 Da |
| Molarity of 1 μg/μl solution | 80.46 μM | Number of G-quadruplexes | No QGRS found |
| G-Score | N/A | Function | Target detection |
| Sequence | GGCGTATGCAGTTTTGTAGGGTTATCAAGGCTTGACGATT | ||
| Applications | Detection of rituximab | ||
Target information
| Type | Detail | Type | Detail |
|---|---|---|---|
| Target ID | Other-31 | Name | Rituximab |
Activity data
 |
Interaction ID | 1009 |
| Target type | Other | |
| Target unique ID | Other-31 | |
| Activity | 82.4 nM | |
| Binding Conditions/Buffer | 20 mM Tris pH 7.6, 100 mM NaCl, 2 mM MgCl2, 5 mM KCl, 1 mM CaCl2, 0.02% v/v Tween 20 |
|
| Assay | Titration of aptamers for heat-treated rituximab binding using ELASA |
|
| PubMed ID | 33151990 |
Similar aptamers
| Aptamer ID | Aptamer chemistry | Sequence | Similarity |
|---|---|---|---|
| Apta_911 | DNA | GGCCATTGTGGACTTCTTTGGGTAATTCAGGGGCTCGATT | |
| Apta_1258 | DNA | GGCGAAGGAGTCATGTAGGTGTGGTCGAGACCGCTGTGCT | |
| Apta_1045 | DNA | GGTGCTCAGGGAACTGTCTGAGGGATCAGGCTTAAGCCTGTCGAGCAGTT | |
| Apta_69 | DNA | AGCGAGTAGGTTGGTGTGGTTGGGGCTCGCT | |
| Apta_71 | DNA | GGCGAGTAGGTTGGTGTGGTTGGGGCTCGCC | |
| Apta_142 | DNA | CGCACATCAGTTTAGCAGCGCCAAAGGCGGAAGCGCA | |
| Apta_216 | DNA | TGGTTGGTTTTTGGTTTTTTTTTTTGGTTT | |
| Apta_260 | DNA | GACGTTAAGCTAGCAGGTGTTAGGTCCCGTGGTGATGAAT | |
| Apta_809 | DNA | GGGTACGTATTTGGTTTATAGATAGTAA | |
| Apta_1093 | DNA | AGGAGGGTAGGTAGTGCTTGGTAGGGAAACTCCGCCGATT | |
| Apta_1238 | DNA | GGTTTTGTGTTTGTGTTTTGTGGTTGTTGT | |
| Apta_1244 | DNA | GGAGATGTCAGTTGTGTGTGTGGTTATGGC | |
| Apta_1255 | DNA | GGCGCATGATCATTCGGTGGGTAAGGTGGTGGTAACGTTG | |
| Apta_1018 | DNA | ATCCCTGCAGTTTGGTAGGGTGCGAGCAACATCAGGCACCTGCAGG | |
| Apta_391 | DNA | ACCGTGGAGGATAGTTCGGTGGCTGTTCAGGGTCTCCTCCACGGT | |
| Apta_835 | DNA | TATGGCGTGGCAAGCTTGGCCCGCTTCTCAAGCATGGTTATCTAC | |
| Apta_979 | DNA | ATGAGTAGTGCGGAGGGATGTGAATACTGACGCGGTCATAGTCGCTGTTGTACCATTGA | |
| Apta_46 | DNA | CGGGTGGGAGTTGTGGGGGGGGGTGGGAGGGTT | |
| Apta_70 | DNA | AGGTCGTAGGTTGGTGTGGTTGGGGCGACCT | |
| Apta_72 | DNA | AGTCAGTAGGTTGGTGTGGTTGGGGCTGACT |
DEV TOOL
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