Aptamer-target interaction descriptor
Aptamer-target interaction information
Interaction ID: 969
Aptamer sequence: CGTACCGGCCAGTGATTACGACGAGACGAGCTTATGCGTATTGATGCCTAACTATCTACA
Target unique ID: Other-16
| Aptamer ID | Aptamer descriptor | Target chemistry | Target name | Affinity | Binding Conditions/Buffer | PubMed ID |
|---|---|---|---|---|---|---|
| Apta_883 | Anti-HSA Structure-switching Aptamer | Other | HSA (Human Serum Albumin) | 20 nM | 50 mM HEPES, 100 mM NaCl, 1 mM MgCl2, 5 mM KCl, 1 mM CaCl2, pH 7.4 | 31580650 |
Structure information of aptamer
| Aptamer Sequence: | CGTACCGGCCAGTGATTACGACGAGACGAGCTTATGCGTATTGATGCCTAACTATCTACA |
| The optimal secondary structure in dot-bracket notation: | ((((..(((..((............))..)))..))))....((((......)))).... |
| The centroid secondary structure in dot-bracket notation: | ............................................................ |
The MFE structure
The Centroid structure
The mountain plot representation
Aptamer information
| Type | Detail | Type | Detail |
|---|---|---|---|
| Aptamer ID | Apta_883 | Description | Anti-HSA Structure-switching Aptamer |
| Aptamer chemistry | DNA | Length | 60 nt |
| GC content | 48.3% | Molecular weight | 18,458.85 Da |
| Molarity of 1 μg/μl solution | 54.17 μM | Number of G-quadruplexes | No QGRS found |
| G-Score | N/A | Function | Targeted binding |
| Sequence | CGTACCGGCCAGTGATTACGACGAGACGAGCTTATGCGTATTGATGCCTAACTATCTACA | ||
| Applications | Binding to HSA | ||
Target information
| Type | Detail | Type | Detail |
|---|---|---|---|
| Target ID | Other-16 | Name | HSA (Human Serum Albumin) |
Activity data
 |
Interaction ID | 969 |
| Target type | Other | |
| Target unique ID | Other-16 | |
| Activity | 20 nM | |
| Binding Conditions/Buffer | 50 mM HEPES, 100 mM NaCl, 1 mM MgCl2, 5 mM KCl, 1 mM CaCl2, pH 7.4 |
|
| Assay | Affinity measurements of HSA-6 using a magnetic bead-based qPCR assay |
|
| PubMed ID | 31580650 |
Similar aptamers
| Aptamer ID | Aptamer chemistry | Sequence | Similarity |
|---|---|---|---|
| Apta_446 | DNA | AGCCATGACGATGTCGTTACGTAGATGCATAGACTCCTAA | |
| Apta_1172 | DNA | GACGCCACTGACTACCCCAGTATCTCTTCAACGCGTATTGAAGTCAGTCGGTCGTCA | |
| Apta_931 | DNA | ATACGACTCACTATTAGGGACCACATAAACATGCATCGCTCAATAACGGGATATTGTTGTGCTAGACTACTGACTACAA | |
| Apta_173 | DNA | AGCAGCACAGAGGTCAGATGGCAGGTTTCGACGTACAATGCTATGGAGGCTTTATGATCGCCTATGCGTGCTACCGTGAA | |
| Apta_438 | DNA | AGCCATGACGATGTCGTTACGTAGATGCAGAGACTCCTAA | |
| Apta_438 | DNA | AGCCATGACGATGTCGTTACGTAGATGCAGAGACTCCTAA | |
| Apta_443 | DNA | GGCCATGACGATGTCGTTACGTAGATGCAGAGACTCCTAA | |
| Apta_444 | DNA | AGCCATTACGATGTCGTTACGTAGATGCAGAGACTCCTAA | |
| Apta_573 | DNA | CGTACAGTGGGCTATATTGCTGACGTAAGAGCTGCTTTCAATGCATTGGCATAGATGTCA | |
| Apta_779 | DNA | TACGGGCTGGATCCACTGTTACGGCGTGTATCCGCTATCAA | |
| Apta_845 | DNA | CCAAACGCGCTGGTTTGGAATGCTTAGAGTTTGATCGATGCCTAA | |
| Apta_932 | DNA | ATACGACTCACTATTAGGGATGTCCACCATATAGATCGATTTAAGTCCCTCGTTATTAATGCTAGACTACTGACTACAA | |
| Apta_287 | DNA | CAGCACCGACCTTGTGCTTTGGGAGTGCTGGTCCAAGGGCGTTAATGGACA | |
| Apta_445 | DNA | AGCCATGACGATGTCGTTACGTAGATGTAGAGACTCCTAA | |
| Apta_639 | DNA | CTAAGCACAGGGAAACCAGCTAATGAGTTAGGCCTGTCCCCCACG | |
| Apta_876 | DNA | GTTGCGAAAGACAACGAATGCTTTGCCTGCCATAATTTGC | |
| Apta_946 | DNA | TACCGGGTAATATGCACACATGCTGATAGCAAGCAATGCA | |
| Apta_962 | DNA | CCACACCGAGATGTTGTGACGGTTCCGATTGGCAAACTGA | |
| Apta_965 | DNA | CACGGCATGTGTGGCCGGATGCCTATATCGGTCGACTGCA | |
| Apta_944 | DNA | ATACGACTCACTATTAGGGACAAAGCTGACAACCCTTTCATAATCTAACTACATTTATGTGCTAGACTACTGACTAC |
DEV TOOL
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