AptaDB: Result

Interaction ID: 829

Aptamer sequence: TGGGGTTATTAATTTTGGGTGGGGGGGAAGATGTAGCATCCGACG

Target unique ID: CRM-CCL-185

Aptamer ID	Aptamer descriptor	Target chemistry	Target name	Affinity	Binding Conditions/Buffer	PubMed ID
Apta_747	S11.b	Cell	vaccinia virus–infected and–uninfected lung cancer A549 cells	47.0 nM	5 mmol MgCl2 and 4.5 g glucose into 1 L of Dulbecco's PBS without calcium and magnesium	19684903

Aptamer Sequence:	TGGGGTTATTAATTTTGGGTGGGGGGGAAGATGTAGCATCCGACG
The optimal secondary structure in dot-bracket notation:	..............(((((((...............)))))))..
The centroid secondary structure in dot-bracket notation:	.((((((((.......................))))).)))....

The MFE structure

The Centroid structure

The mountain plot representation

Type	Detail	Type	Detail
Aptamer ID	Apta_747	Description	S11.b
Aptamer chemistry	DNA	Length	45 nt
GC content	51.1%	Molecular weight	14,123.05 Da
Molarity of 1 μg/μl solution	70.81 μM	Number of G-quadruplexes	3
G-Score	57	Function	Target recognition
Sequence	TGGGGTTATTAATTTTGGGTGGGGGGGAAGATGTAGCATCCGACG
Applications	Recognition of subtype non-small cell lung cancer

Type	Detail	Type	Detail
ATCC ID	CRM-CCL-185	Cell name	vaccinia virus-infected and-uninfected lung cancer A549 cells
Category	Human cells	Organism	Homo sapiens, human
Product type	Certified reference material	Cell type	epithelial cell
Morphology	epithelial	Tissue	Lung
Disease	Carcinoma	Product format	Frozen
Antigen expression	N/A	Genes expressed	N/A
Cell description	N/A
Application(s)	Assay development

No relevant experimental diagram	Interaction ID	829
	Target type	Cell
	Target unique ID	CRM-CCL-185
	Activity	47.0 nM
	Binding Conditions/Buffer	5 mmol MgCl2 and 4.5 g glucose into 1 L of Dulbecco's PBS without calcium and magnesium
	Assay	N/A
	PubMed ID	19684903

Aptamer ID	Aptamer chemistry	Sequence	Similarity
Apta_941	DNA	CGGGTGCCTTAAAGTGTAGGTGGGAGGGGGATGATTATGTACGATCAAGT	58.00%
Apta_862	DNA	TGTGCCAAAGAGAGTGGTGGGGGGGTGGGCGGAACTCGCG	55.56%
Apta_1256	DNA	GATCGGGTGTGGGTGGCGTAAAGGGAGCATCGGACA	55.56%
Apta_73	DNA	GGGGAGTAGGTTGGTGTGGTTGGGGCTCCCC	53.33%
Apta_255	DNA	TAGCGATACTGCGTGGGTTGGGGCGGGTAGGGCCAGCAGTCTCGT	53.33%
Apta_464	DNA	GTCAGATTCCACTATAGTAGGTTGGGTAGGGTGGTCGCAGTGGATGATATGTCGTAGGGG	53.33%
Apta_813	DNA	TAGAGATATGACAGCGGGGAAGGTTAAGAGGCGCTAGGAG	53.33%
Apta_1255	DNA	GGCGCATGATCATTCGGTGGGTAAGGTGGTGGTAACGTTG	53.33%
Apta_596	DNA	GGTGGCTGTTGGTCGAGGCTTATTAGTGTAGTCAATGGAGGCAGGCGACG	52.00%
Apta_1069	DNA	CCGGAGAAAAAAAACTTGATGAGCCAGGAAAACGAGGGTTGGAACGCGACTG	51.92%
Apta_76	DNA	CAGCGCTAGGGCTTTTAGCGTAATGGGTAGGGTGGTGCGGTGCAGATATCGGAATTGGTG	51.67%
Apta_1230	DNA	GGCGATAGGCAGTGTTGCGGGGTCGGAGAGCGAGGTAATAGCGTGTATGGGTGCTGTGTG	51.67%
Apta_41	DNA	CGGTCGCTCCGTGTGGCTTGGGTTGGGTGTGGCAGTGAC	51.11%
Apta_71	DNA	GGCGAGTAGGTTGGTGTGGTTGGGGCTCGCC	51.11%
Apta_266	DNA	TGGATGGTAGCTCGGTCGGGGTGGGTGGGTTGGCAAGTCT	51.11%
Apta_393	DNA	AGGAGGATAGTTCGGTGGCTGTTCAGGGTCTCCTCCT	51.11%
Apta_497	DNA	GTTCGATTGGATTGTGCCGGAAGTGCTGGCTCGAAC	51.11%
Apta_580	DNA	ATGCGGGTATATGGTGCGAGAAAACAAGGGGCATACTGGA	51.11%
Apta_646	DNA	TGGAGCTTGGATTGATGTGGTGTGTGAGTGCGGTGCCC	51.11%
Apta_744	DNA	GTGGCCAGTCACTCAATTGGGTGTAGGGGTGGGGATTGTGGGTTG	51.11%

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