AptaDB: Result

Interaction ID: 266

Aptamer sequence: TAAACCCCAAAACAGTGCAACTAGGTGTAGGTCCCGTGGT

Target unique ID: P08637

Aptamer ID	Aptamer descriptor	Target chemistry	Target name	Affinity	Binding Conditions/Buffer	PubMed ID
Apta_261	CLN0030	Protein	FCG3A_HUMAN	6 nM	DPBS with 0.05% BSA	21531729

Aptamer Sequence:	TAAACCCCAAAACAGTGCAACTAGGTGTAGGTCCCGTGGT
The optimal secondary structure in dot-bracket notation:	......(((......((((......)))).......))).
The centroid secondary structure in dot-bracket notation:	......(((......((((......)))).......))).

The MFE structure

The Centroid structure

The mountain plot representation

Type	Detail	Type	Detail
Aptamer ID	Apta_261	Description	CLN0030
Aptamer chemistry	DNA	Length	40 nt
GC content	50.0%	Molecular weight	12,553.88 Da
Molarity of 1 μg/μl solution	79.66 μM	Number of G-quadruplexes	No QGRS found
G-Score	N/A	Function	Targeted binding
Sequence	TAAACCCCAAAACAGTGCAACTAGGTGTAGGTCCCGTGGT
Applications	Binding to target proteins

Type	Detail	Type	Detail
Uniprot ID	P08637	Protein name	Low affinity immunoglobulin gamma Fc region receptor III-A (IgG Fc receptor III-A) (CD16-II) (CD16a antigen) (Fc-gamma RIII-alpha) (Fc-gamma RIII) (Fc-gamma RIIIa) (FcRIII) (FcRIIIa) (FcgammaRIIIA) (FcR-10) (IgG Fc receptor III-2) (CD antigen CD16a)
Gene name(s)	FCGR3A CD16A FCG3 FCGR3 IGFR3	Organism	Low affinity immunoglobulin gamma Fc region receptor III-A (IgG Fc receptor III-A) (CD16-II) (CD16a antigen) (Fc-gamma RIII-alpha) (Fc-gamma RIII) (Fc-gamma RIIIa) (FcRIII) (FcRIIIa) (FcgammaRIIIA) (FcR-10) (IgG Fc receptor III-2) (CD antigen CD16a)
Status	reviewed in uniprot database	Length	254
Mass	29,089	Activity regulation	N/A
Involvement in disease	Immunodeficiency 20 (IMD20)	Catalytic activity	N/A
PDB ID(s)	3AY4;3SGJ;3SGK;3WN5;5BW7;5D6D;5ML9;5MN2;5VU0;5XJE;5XJF;5YC5;7SEG;
Function	Receptor for the invariable Fc fragment of immunoglobulin gamma (IgG).

No relevant experimental diagram	Interaction ID	266
	Target type	Protein
	Target unique ID	P08637
	Activity	6 nM
	Binding Conditions/Buffer	DPBS with 0.05% BSA
	Assay	N/A
	PubMed ID	21531729

Aptamer ID	Aptamer chemistry	Sequence	Similarity
Apta_262	DNA	ACGGACTCGCAAAAGGTGGAACAGGAGTGGGCCCCGCGGC	62.50%
Apta_730	DNA	ACCAAACACAGATGCAACCTGACTTCTAACGTCATTTGGTG	56.10%
Apta_1218	DNA	CGACACCACACAGCAGTAAGCACTACAACATAGTGGTCTAGACTATCTCGGGCCGGTG	55.17%
Apta_570	DNA	GGCAAGATGTGCCCAGAACAGTTGCTTGTATGGTGGGGAGCGTCCATATTGGCTTAAAC	52.54%
Apta_347	DNA	AAAAAAAAAAAAGTACGTTCAGGAGCAGTGCGA	52.50%
Apta_676	DNA	TCAGTCCCGATCAGGTGTGGGTGGCATTGG	52.50%
Apta_822	DNA	TAGCCCTTCAACATAGTAATATCTCTGCATTCTGTGATG	52.50%
Apta_1191	DNA	TAATACTACCAACTTCTTTGCCTGGCGTAAGTAACAGTCA	52.50%
Apta_939	DNA	TTGCCCACCGTACTGTGCAGGTCGAACTACAGGCACGTCGTG	52.38%
Apta_340	DNA	TACTCAGGGCACTGCAAGCAATTGTGGTCCCAATGGGCTGAGTA	52.27%
Apta_1228	DNA	GGCCACCAAACCACACCGTCGCAACCGCGAGAACCGAAGTAGTGATCATGTCCCTGCGTG	51.67%
Apta_585	DNA	GATCGAGGGCAGCGATAGCTGGGCTAATAAGGTTAGCCCCATCGGTC	51.06%
Apta_1267	DNA	GGCACGGCAAAGGGGTACAGCCTACCGAACCGTGGCTGTAAGGGTGGTTGTGGTGTG	50.88%
Apta_1219	DNA	GCGCAGAACCGACAGCAAAACGGAAGTCCACCACGACTATTGGTGCCCAATCTACCGTA	50.85%
Apta_1265	DNA	CACGCACACAACAGCCAATAATGTATAACGCTGTCCACTGTGTGGTGTCCCCCGCGTCG	50.85%
Apta_63	DNA	GACCCGTGGTAGGGTAGGATGGGGTGGTC	50.00%
Apta_126	DNA	TCCTCATATAGAGTGCGGGGCGTGT	50.00%
Apta_188	DNA	AAAAAAACTTTAAATCTGAGATCTCAAAAT	50.00%
Apta_324	DNA	CAAACAATCAAACAGCAGTGGGGTG	50.00%
Apta_324	DNA	CAAACAATCAAACAGCAGTGGGGTG	50.00%

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