AptaDB: Result

Interaction ID: 1069

Aptamer sequence: CCAGGAGGACCCTATTCTCGTGTATCGACGAGATCCAGTG

Target unique ID: 43504

Aptamer ID	Aptamer descriptor	Target chemistry	Target name	Affinity	Binding Conditions/Buffer	PubMed ID
Apta_985	HPA-2	Cell	Helicobacter pylori	19.3 nM	100 mM NaCl, 5 mM KCl, 50 mM Tris-HCl, and 1 mM MgCl2, pH 7.5	33585756

Aptamer Sequence:	CCAGGAGGACCCTATTCTCGTGTATCGACGAGATCCAGTG
The optimal secondary structure in dot-bracket notation:	..(((.....)))..((((((......)))))).......
The centroid secondary structure in dot-bracket notation:	...............((((((......)))))).......

The MFE structure

The Centroid structure

The mountain plot representation

Type	Detail	Type	Detail
Aptamer ID	Apta_985	Description	HPA-2
Aptamer chemistry	DNA	Length	40 nt
GC content	55.0%	Molecular weight	12,296.90 Da
Molarity of 1 μg/μl solution	81.32 μM	Number of G-quadruplexes	No QGRS found
G-Score	N/A	Function	Aptasensor
Sequence	CCAGGAGGACCCTATTCTCGTGTATCGACGAGATCCAGTG
Applications	Detect H. pylori with the naked eye for 5 min using illumination from a hand-held flashlight

Type	Detail	Type	Detail
ATCC ID	43504	Cell name	Helicobacter pylori
Category	N/A	Organism	N/A
Product type	N/A	Cell type	N/A
Morphology	N/A	Tissue	N/A
Disease	N/A	Product format	Frozen
Antigen expression	N/A	Genes expressed	N/A
Cell description	Whole-genome sequenced bacterial type strain isolated from the human gastric antrum. This strain can be used in enteric research or as a quality control strain.
Application(s)	Bioinformatics; Enteric disease research; Infectious disease research; Media testing; Quality control

	Interaction ID	1069
	Target type	Cell
	Target unique ID	43504
	Activity	19.3 nM
	Binding Conditions/Buffer	100 mM NaCl, 5 mM KCl, 50 mM Tris-HCl, and 1 mM MgCl2, pH 7.5
	Assay	Saturation curve of aptamer HPA-2
	PubMed ID	33585756

Aptamer ID	Aptamer chemistry	Sequence	Similarity
Apta_158	DNA	CACAGGCTACGGCACGTAGAGCATCACCATGATCCTGTG	57.50%
Apta_552	DNA	CACCTGGGGGAGTATTGCGGAGGAAGGTTCCAGGTG	57.50%
Apta_1138	DNA	GCAGTGTGGGCGAATCTATGCGTACCGTTCGATATCGTG	57.50%
Apta_163	DNA	GCGCATGACCATTGATGTCTGCACCATCAGAGGCAGAG	55.00%
Apta_189	DNA	AGGAACCCTTTACCTCTGAGATCTCGGAAT	55.00%
Apta_190	DNA	AGGAACCCTTTAGGTCTGAGATCTCGGAAT	55.00%
Apta_339	DNA	CACAGGCTACGGCACGTAGAGCATCACCATGATCCTGTGT	55.00%
Apta_1203	DNA	CCCTGCGGGGCTACCCGATATGTGTCCGAGTGGTG	55.00%
Apta_1254	DNA	GGCAGTGTGGGCGAATCTATGCGTACCGTTCGATATCGTG	55.00%
Apta_779	DNA	TACGGGCTGGATCCACTGTTACGGCGTGTATCCGCTATCAA	53.66%
Apta_1279	DNA	TTCCAAGACCTGACCGTAATCGTCAAATGTGTTATTGGAGGGGGACTAGCCCCCGGAGGG	53.33%
Apta_592	DNA	CTCTCGGGACGACCACTACGCATAGTTTCTATCGCCAGGAAGGGTCGTCCC	52.94%
Apta_75	DNA	CACTGGTAGGTTGGTGTGGTTGGGGCCAGTG	52.50%
Apta_162	DNA	CCGTACATACTACGTACGTACGTGAACAGAGGCAGAG	52.50%
Apta_184	DNA	AGGAAGGCTTTAGGTCTGAGATCTCGGAAT	52.50%
Apta_185	DNA	ACCAAGGCTTTAGGTCTGAGATCTCCCAAT	52.50%
Apta_186	DNA	AGGAACGCTTTAGGTCTGAGATCTCGGAAT	52.50%
Apta_191	DNA	AGGAAGGCTTTACCTCTGAGATCTCGGAAT	52.50%
Apta_192	DNA	AGGAAGGCTTTAGCTCTGAGATCTCGGAAT	52.50%
Apta_204	DNA	CCAAGGCTTTAGGTCTGAGATCTCCC	52.50%

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