Aptamer-target interaction descriptor
Aptamer-target interaction information
Interaction ID: 463
Aptamer sequence: AGCTCCAGAAGATAAATTACAGGGAGAGTAAACTTTGCAAACACAACAATACCATTCCGGAACGTTCTTAACACAACTAGGATACTATGACCCC
Target unique ID: Q27102
Aptamer ID Aptamer descriptor Target chemistry Target name Affinity Binding Conditions/Buffer PubMed ID
Apta_458 AP65_A5 Protein Q27102_TRIVA 1205 nM PBS-Tween 29972299
Structure information of aptamer
Aptamer Sequence: AGCTCCAGAAGATAAATTACAGGGAGAGTAAACTTTGCAAACACAACAATACCATTCCGGAACGTTCTTAACACAACTAGGATACTATGACCCC
The optimal secondary structure in dot-bracket notation: .....................((((..(((....(((......)))...)))..))))((..((((((((.......)))))....)))..)).
The centroid secondary structure in dot-bracket notation: ..............................................................................................
The MFE structure
The Centroid structure
The mountain plot representation
Aptamer information
Type Detail Type Detail
Aptamer ID Apta_458 Description AP65_A5
Aptamer chemistry DNA Length 94 nt
GC content 40.4% Molecular weight 28,895.63 Da
Molarity of 1 μg/μl solution 34.61 μM Number of G-quadruplexes No QGRS found
G-Score N/A Function Aptasensor
Sequence AGCTCCAGAAGATAAATTACAGGGAGAGTAAACTTTGCAAACACAACAATACCATTCCGGAACGTTCTTAACACAACTAGGATACTATGACCCC
Applications Diagnostic assays for the reliable and rapid detection of T. vaginalis in vaginal swabs
Target information
Type Detail Type Detail
Uniprot ID Q27102 Protein name AP65-3 adhesin
Gene name(s) N/A Organism AP65-3 adhesin
Status unreviewed in uniprot database Length 567
Mass 63,134 Activity regulation N/A
Involvement in disease N/A Catalytic activity N/A
PDB ID(s)
N/A
Function N/A
Activity data
Interaction ID 463
Target type Protein
Target unique ID Q27102
Activity 1205 nM
Binding Conditions/Buffer

PBS-Tween
Assay

Affinity dissociation constants KD of the full length aptamer candidates calculated by SPR (ii)
PubMed ID 29972299
Similar aptamers
Aptamer ID Aptamer chemistry Sequence Similarity
Apta_457 DNA AGCTCCAGAAGATAAATTACAGGGGATCAGTAAGGTTGAGACGGCCTGAATCTATCGTGGAGACCACGCGACGCAACTAGGATACTATGACCCC 72.34%
Apta_455 DNA AGCTCCAGAAGATAAATTACAGGGGCCGGGGTGGCTCAGGCAAGGGGTTGACCTGTCGTAGGGATTGTTTTAACAACTAGGATACTATGACCCC 67.02%
Apta_454 DNA AGCTCCAGAAGATAAATTACAGGTGAGGGCGGGCGGGTGGTTGTAATATGATCGAATGGTATATGTGTGTTTGCAACTAGGATACTATGACCCCG 65.26%
Apta_459 DNA AGCTCCAGAAGATAAATTACAGGGGCGGGGGGGCGGGGGAGGCGGAAGGCCTGCTAAAGTCGTTGTGAGCGAACCAACTAGGATACTATGACCCC 65.26%
Apta_456 DNA AGCTCCAGAAGATAAATTACAGGTGGGTGGGTGGGCGGTGGAATTTAGCGGCGGAGCTCTGTGTGTGTTAGGGCAACTAGGATACTATGACCCC 64.89%
Apta_1112 DNA ATCCAGAGTGACGCAGCAGGGCACATTGTTCACACACAGATCACATTACGGAAAACACAACTACACGAAATGTCGTTGGTGGCCC 54.26%
Apta_550 DNA GGTAATACGACTCACTATAGGGAGATACCAGCTTATTCAATTTTACAGAACAACCAACGTCGCTCCGGGTACTTCTTCATCGAGATAGTAAGTGCAATCT 54.00%
Apta_61 DNA AGCAGCACAGAGGTCAGATGGCAGGTAAGCAGGCGGCTCACAAAACCATTCGCATGCGGCCCTATGCGTGCTACCGTGAA 52.13%
Apta_83 DNA GGCTTTACACTTTATGCTTCCGTAAAAACACAAACACACGCACATACATAAAATAACAATTTCACACAGGAAACAG 52.13%
Apta_1113 DNA CCGCCCAAATCCCTAAGAGCACAAACACCAAACACAACCACCCCAACCAGACACACTACACACGCA 52.13%
Apta_790 DNA GGGAGACAAGAATAAACGCTCAAGAAGTGAAAATGACAGAACACAACATTCGACAGGAGGCTCACAACAGGC 51.06%
Apta_881 DNA AGCGTCGAATACCACTACAGCCCGCACTCAACCACCGTTCCTTTGTTTAATTTTGCACATCTAATGGAGCTCGTGGTCAG 51.06%
Apta_944 DNA ATACGACTCACTATTAGGGACAAAGCTGACAACCCTTTCATAATCTAACTACATTTATGTGCTAGACTACTGACTAC 51.06%
Apta_1031 DNA GGAGACCGCTTAAGCTTAAAGGAGCGGTTACGAATGCGATGACTTAGGTACCATTGCACTACGGTACCTAAACAGTTCCTTTGGATCCGAATTCGCCGC 50.51%
Apta_107 DNA AGCAGCACAGAGGTCAGATGTTCATTTCAGTTGACCGATAGCATTGAGCAATGATCTATTCCTATGCGTGCTACCGTGAA 50.00%
Apta_107 DNA AGCAGCACAGAGGTCAGATGTTCATTTCAGTTGACCGATAGCATTGAGCAATGATCTATTCCTATGCGTGCTACCGTGAA 50.00%
Apta_177 DNA AGCAGCACAGAGGTCAGATGCCATAGGTGCCTGAATTGTCCCAAACATTCGCATGATCGACCTATGCGTGCTACCGTGAA 50.00%
Apta_248 DNA GGCTTTACACTTTATGCTTCCGGCCGAGGATTTTCATACCCCGCACGAACGCATAACAATTTCACACAGGAAACAG 50.00%
Apta_401 DNA ATCCAGAGTGACGCAGCAGATAAGTAGGTATCCGTTTGAAAAACTTTTCTGACCGTCCGACTATGGACACGGTGGCTTAGT 50.00%
Apta_931 DNA ATACGACTCACTATTAGGGACCACATAAACATGCATCGCTCAATAACGGGATATTGTTGTGCTAGACTACTGACTACAA 50.00%

ABOUT

AptaDB is an online database we developed to integrate comprehensive information about aptamer.
The detail of this database is described here:

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