AptaDB: Result

Interaction ID: 427

Aptamer sequence: ATCTACGAATTCATCAGGGCTAAAGAGTGCAGAGTTACTTAGCCCGTGA

Target unique ID: P83673

Aptamer ID	Aptamer descriptor	Target chemistry	Target name	Affinity	Binding Conditions/Buffer	PubMed ID
Apta_421	Aptasensor	Protein	LYS1_CRAVI	0.1 fM	50 mM NaCl, 10 mM Tris-HCL, 10 mM MgCl2, 1 mM dithiothreitol, pH 7.9	21826311

Aptamer Sequence:	ATCTACGAATTCATCAGGGCTAAAGAGTGCAGAGTTACTTAGCCCGTGA
The optimal secondary structure in dot-bracket notation:	.............(((((((((...((((......)))))))))).)))
The centroid secondary structure in dot-bracket notation:	..............((((((((...((((......)))))))))).)).

The MFE structure

The Centroid structure

The mountain plot representation

Type	Detail	Type	Detail
Aptamer ID	Apta_421	Description	Aptasensor
Aptamer chemistry	DNA	Length	49 nt
GC content	44.9%	Molecular weight	15,128.75 Da
Molarity of 1 μg/μl solution	66.10 μM	Number of G-quadruplexes	No QGRS found
G-Score	N/A	Function	Aptasensor
Sequence	ATCTACGAATTCATCAGGGCTAAAGAGTGCAGAGTTACTTAGCCCGTGA
Applications	Detection of lysozyme

Type	Detail	Type	Detail
Uniprot ID	P83673	Protein name	Lysozyme 1 (EC 3.2.1.17) (1,4-beta-N-acetylmuramidase 1) (Invertebrate-type lysozyme 1) (cv-lysozyme 1)
Gene name(s)	lysoz1 lysoz	Organism	Lysozyme 1 (EC 3.2.1.17) (1,4-beta-N-acetylmuramidase 1) (Invertebrate-type lysozyme 1) (cv-lysozyme 1)
Status	reviewed in uniprot database	Length	184
Mass	19,986	Activity regulation	N/A
Involvement in disease	N/A	Catalytic activity	Reaction=Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins
PDB ID(s)	N/A
Function	Has antibacterial activity against the Gram-positive bacteria L.garvieae, M.luteus and Enterococcus sp.

No relevant experimental diagram	Interaction ID	427
	Target type	Protein
	Target unique ID	P83673
	Activity	0.1 fM
	Binding Conditions/Buffer	50 mM NaCl, 10 mM Tris-HCL, 10 mM MgCl2, 1 mM dithiothreitol, pH 7.9
	Assay	N/A
	PubMed ID	21826311

Aptamer ID	Aptamer chemistry	Sequence	Similarity
Apta_1118	DNA	GGGAATGGATCCACATCTACGAATTCATCAGGGCTAAAGAGTGCAGAGTTACTTAGTTCACTGCAGACTTGACGAAGCTT	61.25%
Apta_419	DNA	ATCAGGGCTAAAGAGTGCAGAGTTACTTAG	61.22%
Apta_385	DNA	ACAGATACGGAACTACAGAGGTCAATTACGGTGGCCACGC	55.10%
Apta_438	DNA	AGCCATGACGATGTCGTTACGTAGATGCAGAGACTCCTAA	55.10%
Apta_438	DNA	AGCCATGACGATGTCGTTACGTAGATGCAGAGACTCCTAA	55.10%
Apta_444	DNA	AGCCATTACGATGTCGTTACGTAGATGCAGAGACTCCTAA	55.10%
Apta_1152	DNA	GACAAGGATAAATCCTTCAATGAAGTGGGTCACTCATCTGTGA	55.10%
Apta_405	DNA	TCTAGCCCACTGCATAGAGGTAGCCACGTATGTGGGTGTTACCCATTCGTAGCTACCGGTG	54.10%
Apta_288	DNA	ATCCAGAGTGACGCAGCATTTCATCGGGTCCAAAAGGGGCTGCTCGGGATTGCGGATATGGACACGT	53.73%
Apta_664	DNA	CACGCAACAACACAACATGCCCAGCGCCTGGAACATATCCTATGAGTTAGTCCGCCCACA	53.33%
Apta_983	DNA	ATGGGAACAGAGCGGCGCAGAGACCCAATGCCACGAGTACCTGACCCTATCAACCCGTGA	53.33%
Apta_166	DNA	ATCGCGCTCTCCTGCTTAAGCAGCTATCAAATAGCCCACT	53.06%
Apta_283	DNA	ACTCCGTCATCTTTAGTGGCCCCAATGTCGTTATCACCGA	53.06%
Apta_291	DNA	AAAAATCTAGGCGCTGAAGCCCCGCTTCCTTACCTTCAC	53.06%
Apta_387	DNA	CTTTAATGCCCTTCACTAGGTCTAAGCTACTACTTACCCG	53.06%
Apta_443	DNA	GGCCATGACGATGTCGTTACGTAGATGCAGAGACTCCTAA	53.06%
Apta_445	DNA	AGCCATGACGATGTCGTTACGTAGATGTAGAGACTCCTAA	53.06%
Apta_446	DNA	AGCCATGACGATGTCGTTACGTAGATGCATAGACTCCTAA	53.06%
Apta_666	DNA	TCGACCTCGCGCGAGGAGGGTGGAGGGTCGTAGAGCGCGTA	53.06%
Apta_847	DNA	CACTAGGATCTAGGGAAAAATCTCGTAAATACTATACTCCTGAGC	53.06%

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