AptaDB: Result

Interaction ID: 262

Aptamer sequence: GGCAGAAGAAATATCGAAACCCAGAATGGTCGGCCAGGCG

Target unique ID: P08637

Aptamer ID	Aptamer descriptor	Target chemistry	Target name	Affinity	Binding Conditions/Buffer	PubMed ID
Apta_257	CLN0015	Protein	FCG3A_HUMAN	24 nM	DPBS with 0.05% BSA	21531729

Aptamer Sequence:	GGCAGAAGAAATATCGAAACCCAGAATGGTCGGCCAGGCG
The optimal secondary structure in dot-bracket notation:	(((.((....((.((........))))..)).))).....
The centroid secondary structure in dot-bracket notation:	(((.((........(........).....)).))).....

The MFE structure

The Centroid structure

The mountain plot representation

Type	Detail	Type	Detail
Aptamer ID	Apta_257	Description	CLN0015
Aptamer chemistry	DNA	Length	40 nt
GC content	55.0%	Molecular weight	12,661.96 Da
Molarity of 1 μg/μl solution	78.98 μM	Number of G-quadruplexes	No QGRS found
G-Score	N/A	Function	Targeted binding
Sequence	GGCAGAAGAAATATCGAAACCCAGAATGGTCGGCCAGGCG
Applications	Binding to target proteins

Type	Detail	Type	Detail
Uniprot ID	P08637	Protein name	Low affinity immunoglobulin gamma Fc region receptor III-A (IgG Fc receptor III-A) (CD16-II) (CD16a antigen) (Fc-gamma RIII-alpha) (Fc-gamma RIII) (Fc-gamma RIIIa) (FcRIII) (FcRIIIa) (FcgammaRIIIA) (FcR-10) (IgG Fc receptor III-2) (CD antigen CD16a)
Gene name(s)	FCGR3A CD16A FCG3 FCGR3 IGFR3	Organism	Low affinity immunoglobulin gamma Fc region receptor III-A (IgG Fc receptor III-A) (CD16-II) (CD16a antigen) (Fc-gamma RIII-alpha) (Fc-gamma RIII) (Fc-gamma RIIIa) (FcRIII) (FcRIIIa) (FcgammaRIIIA) (FcR-10) (IgG Fc receptor III-2) (CD antigen CD16a)
Status	reviewed in uniprot database	Length	254
Mass	29,089	Activity regulation	N/A
Involvement in disease	Immunodeficiency 20 (IMD20)	Catalytic activity	N/A
PDB ID(s)	3AY4;3SGJ;3SGK;3WN5;5BW7;5D6D;5ML9;5MN2;5VU0;5XJE;5XJF;5YC5;7SEG;
Function	Receptor for the invariable Fc fragment of immunoglobulin gamma (IgG).

No relevant experimental diagram	Interaction ID	262
	Target type	Protein
	Target unique ID	P08637
	Activity	24 nM
	Binding Conditions/Buffer	DPBS with 0.05% BSA
	Assay	N/A
	PubMed ID	21531729

Aptamer ID	Aptamer chemistry	Sequence	Similarity
Apta_386	DNA	GGAAAAGATGGTATGGGCCCTAGAAAGTCCACCCGGCGCC	57.50%
Apta_1068	DNA	CGGGACAAGACAACGAACGAACAGGAAGAGAACCGGAATGCAGACGTCAGGG	55.77%
Apta_1213	DNA	GGACTTGAAGAAAAGGGCGACACGCGAAGTCGATGTCGCGTCTGCCTGAAGTCA	55.56%
Apta_142	DNA	CGCACATCAGTTTAGCAGCGCCAAAGGCGGAAGCGCA	55.00%
Apta_324	DNA	CAAACAATCAAACAGCAGTGGGGTG	55.00%
Apta_324	DNA	CAAACAATCAAACAGCAGTGGGGTG	55.00%
Apta_385	DNA	ACAGATACGGAACTACAGAGGTCAATTACGGTGGCCACGC	55.00%
Apta_1206	DNA	GGCAGCAGCAATGTAACACTGTGTGTATGTGTTGG	55.00%
Apta_512	DNA	ATAGGACGATTATCGAAAATCACCAGATTGGACCCTGGTTAACGAT	54.35%
Apta_1219	DNA	GCGCAGAACCGACAGCAAAACGGAAGTCCACCACGACTATTGGTGCCCAATCTACCGTA	54.24%
Apta_1069	DNA	CCGGAGAAAAAAAACTTGATGAGCCAGGAAAACGAGGGTTGGAACGCGACTG	53.85%
Apta_1220	DNA	TGGCGACAAGAAGACGTACAAACACGCACCAGGCCGGAGTGGAGTATTCTGAGGTCGG	53.45%
Apta_154	RNA	ACACGCGAGAUAGAGCGAGGCCUCCAAAAAUGGCCACGCCAGGAAGCAAGU	52.94%
Apta_503	DNA	ACTTTTGAATGTGGCAACAAATTCGACAGG	52.50%
Apta_586	DNA	GGGAGACAAGGAAAATCCTTCAATGAAGTGGGTCGACA	52.50%
Apta_1204	DNA	GGCACGATGTGGCTACATCGATCGCGGTACTGGTG	52.50%
Apta_1204	DNA	GGCACGATGTGGCTACATCGATCGCGGTACTGGTG	52.50%
Apta_937	DNA	TTGCCCACAGATCTGTGGAAGCCGAACCGCGTGCTAGTCGTG	52.38%
Apta_1025	DNA	GAAGAGTAGATGAAACGTTTTTTCGCCCGATAAAAGGGACGTGCGTCAGACA	51.92%
Apta_684	DNA	GGCGGACCAAGGGGACACCACAGATGAATGTACAGTACCATGTTACTGCGCCCGTAGGTG	51.67%

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