Aptamer-target interaction descriptor
Aptamer-target interaction information
Interaction ID: 1005
Aptamer sequence: TAGTATGGACTTGTCTTCTTGTCAGAGTCTGGCAGCACGT
Target unique ID: Other-31
| Aptamer ID | Aptamer descriptor | Target chemistry | Target name | Affinity | Binding Conditions/Buffer | PubMed ID |
|---|---|---|---|---|---|---|
| Apta_912 | C2 | Other | Rituximab | 65.8 nM | 20 mM Tris pH 7.6, 100 mM NaCl, 2 mM MgCl2, 5 mM KCl, 1 mM CaCl2, 0.02% v/v Tween 20 | 33151990 |
Structure information of aptamer
| Aptamer Sequence: | TAGTATGGACTTGTCTTCTTGTCAGAGTCTGGCAGCACGT |
| The optimal secondary structure in dot-bracket notation: | ..((..((((((............)))))).))....... |
| The centroid secondary structure in dot-bracket notation: | ...................((((((...))))))...... |
The MFE structure
The Centroid structure
The mountain plot representation
Aptamer information
| Type | Detail | Type | Detail |
|---|---|---|---|
| Aptamer ID | Apta_912 | Description | C2 |
| Aptamer chemistry | DNA | Length | 40 nt |
| GC content | 47.5% | Molecular weight | 12,323.91 Da |
| Molarity of 1 μg/μl solution | 81.14 μM | Number of G-quadruplexes | No QGRS found |
| G-Score | N/A | Function | Target detection |
| Sequence | TAGTATGGACTTGTCTTCTTGTCAGAGTCTGGCAGCACGT | ||
| Applications | Detection of rituximab | ||
Target information
| Type | Detail | Type | Detail |
|---|---|---|---|
| Target ID | Other-31 | Name | Rituximab |
Activity data
 |
Interaction ID | 1005 |
| Target type | Other | |
| Target unique ID | Other-31 | |
| Activity | 65.8 nM | |
| Binding Conditions/Buffer | 20 mM Tris pH 7.6, 100 mM NaCl, 2 mM MgCl2, 5 mM KCl, 1 mM CaCl2, 0.02% v/v Tween 20 |
|
| Assay | Titration of aptamers for heat-treated rituximab binding using ELASA |
|
| PubMed ID | 33151990 |
Similar aptamers
| Aptamer ID | Aptamer chemistry | Sequence | Similarity |
|---|---|---|---|
| Apta_191 | DNA | AGGAAGGCTTTACCTCTGAGATCTCGGAAT | |
| Apta_973 | DNA | TATGTAATGTTGACGTAATTTATCTCTGTGAGAATAAGCAGGTGGTATCC | |
| Apta_184 | DNA | AGGAAGGCTTTAGGTCTGAGATCTCGGAAT | |
| Apta_192 | DNA | AGGAAGGCTTTAGCTCTGAGATCTCGGAAT | |
| Apta_497 | DNA | GTTCGATTGGATTGTGCCGGAAGTGCTGGCTCGAAC | |
| Apta_1083 | DNA | TGCTGTTGTCACCTGCCTCGTCTCCCTCGT | |
| Apta_1176 | DNA | AGTATGATATCGGTGTTTATGGTGTCTGTCTTCATACT | |
| Apta_596 | DNA | GGTGGCTGTTGGTCGAGGCTTATTAGTGTAGTCAATGGAGGCAGGCGACG | |
| Apta_1045 | DNA | GGTGCTCAGGGAACTGTCTGAGGGATCAGGCTTAAGCCTGTCGAGCAGTT | |
| Apta_569 | DNA | TGCGCATGTGAAAGGTTGCCTAACTGGACAGGGTTTAGGAGCGACTAGACACAG | |
| Apta_733 | DNA | TAGGCAGTGGTTTGACGTCCGCATGTTGGGAATAGCCACGCCT | |
| Apta_391 | DNA | ACCGTGGAGGATAGTTCGGTGGCTGTTCAGGGTCTCCTCCACGGT | |
| Apta_835 | DNA | TATGGCGTGGCAAGCTTGGCCCGCTTCTCAAGCATGGTTATCTAC | |
| Apta_597 | DNA | TACTGGGCTGGGCTTGGATTAGATCACAGTGGAACATACAGGACACACG | |
| Apta_1162 | DNA | AGAGGCTACAGCGATAAGTCGACATTGCTGACCGTACCTAGTAATACGT | |
| Apta_571 | DNA | ACCTGCGATAGGTAGTTTGTTTCTGTTGCCCTAGCGTCCGTCGTAACAAGTCA | |
| Apta_621 | DNA | AAGCTTGCTTTATAGCCTGCAGCGATTCTTGATCGGAAAAGGCTGAGAGCTACGC | |
| Apta_1278 | DNA | CCATGATTCAACTTTACTGGTCTTGTCTTGGCTAGTCGTGTGTCATTCCCTAAGG | |
| Apta_979 | DNA | ATGAGTAGTGCGGAGGGATGTGAATACTGACGCGGTCATAGTCGCTGTTGTACCATTGA | |
| Apta_69 | DNA | AGCGAGTAGGTTGGTGTGGTTGGGGCTCGCT |
DEV TOOL
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