AptaDB: Result

Interaction ID: 935

Aptamer sequence: UCCCGAUUACUGUACAUACCUUAGCCCAUAGCUGGCUGC

Target unique ID: Other-1

Aptamer ID	Aptamer descriptor	Target chemistry	Target name	Affinity	Binding Conditions/Buffer	PubMed ID
Apta_849	Mitomer2	Other	Mitochondria	N/A	20mM Tris-HCl, 2mM KCl, 40mM NaCl, 1mM MgCl2, 250mM Sucrose, pH=7.5	25087963

Aptamer Sequence:	UCCCGAUUACUGUACAUACCUUAGCCCAUAGCUGGCUGC
The optimal secondary structure in dot-bracket notation:	.....................(((((.......))))).
The centroid secondary structure in dot-bracket notation:	.....................(((((.......))))).

The MFE structure

The Centroid structure

The mountain plot representation

Type	Detail	Type	Detail
Aptamer ID	Apta_849	Description	Mitomer2
Aptamer chemistry	RNA	Length	39 nt
GC content	51.3%	Molecular weight	12,323.31 Da
Molarity of 1 μg/μl solution	81.15 μM	Number of G-quadruplexes	No QGRS found
G-Score	N/A	Function	Targeted binding
Sequence	UCCCGAUUACUGUACAUACCUUAGCCCAUAGCUGGCUGC
Applications	Binding to mitochondria

Type	Detail	Type	Detail
Target ID	Other-1	Name	Mitochondria

	Interaction ID	935
	Target type	Other
	Target unique ID	Other-1
	Activity	N/A
	Binding Conditions/Buffer	20mM Tris-HCl, 2mM KCl, 40mM NaCl, 1mM MgCl2, 250mM Sucrose, pH=7.5
	Assay	Binding Affifinities of Truncated Mitomer2 (Short Mitomer2)
	PubMed ID	25087963

Aptamer ID	Aptamer chemistry	Sequence	Similarity
Apta_374	RNA	GUCCCGUGCGCAAAAGUUCUUAGCGCUAGCAGUCCUAGUUGC	54.76%
Apta_855	RNA	UCACUGUUAUCCGAUAGCAGCGCGGGAUGA	53.85%
Apta_304	RNA	CGGCCGAUAGAAAGACUACUUGAGCCCUUAAAUGAGGUUAUGUGCGGCCG	52.00%
Apta_93	RNA	CUCCGCUAUCUAACGUAUGAUAGAAUGGAUGACUA	51.28%
Apta_313	RNA	UGCCCUGCCCUCACCCGUUAGCCUGAGCGCCCCGCA	51.28%
Apta_243	RNA	GCUUGAAGCUAGCAGUAAGACUAGCGCUACGGAUGGGUGUGCG	51.16%
Apta_426	RNA	UGCCGCUAUAAUGCACGGAUUUAAUCGCCGUAGAAAAGCAUGUCAAAGCCG	50.98%
Apta_270	RNA	CUGUCGAACAUGCUGAGGGUAACGUACUGGCAAGCUCACCUCAGCGUAGCUAa	50.94%
Apta_431	RNA	CAGGCAUGCCUAGCUAAGCAGCCCAUGGCUUAUGCGCGGAAUAUUGGCUUCCGUUC	50.00%
Apta_133	RNA	GGGAGGACGAUGCGGUGAGUCGUUCCCUUCGUCCCCAGACGACUCGCCCGA	49.02%
Apta_425	RNA	UGCCGCCAUAUCACACGGAUUUAAUCGCCGUAGAAAAGCAUGUCAAAGCCG	49.02%
Apta_1122	RNA	ACAACCCGGAACAACGUCUAACAGUGUACCAUAACCCGGCAUUCA	48.89%
Apta_1	RNA	ACGAAGCUUGAUCCCGUUUGCCGGUCGAUCGCUUCGA	48.72%
Apta_51	RNA	GCCUUAGUAACGUGCUUUGAUGUCGAUUCGACAGGAGGC	48.72%
Apta_87	RNA	UACCGACUAGCAAAACCUGCUGGCGACGUUUAGAU	48.72%
Apta_97	RNA	UUGUCGUCUUCUCCAGUUAGUCAACGAACUUGUGU	48.72%
Apta_152	RNA	UUACCACGCGCUCUUAACUGCUAGCGCCAUGGC	48.72%
Apta_711	RNA	GGCGAUACCAGCCGAAAGGCCCUUGGCAGCGUC	48.72%
Apta_848	RNA	CACCACGAUCACGGUUUCCCUCGCAGGUAAGGUGUAGA	48.72%
Apta_242	RNA	GCUUCCAGGAAGAGAAGUGUCAUGUGAUCAGUCCUGGUGGGUGG	47.73%

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