AptaDB: Result

Interaction ID: 426

Aptamer sequence: AGGGACGGGCTAAGTAACTGTGGAGGGT

Target unique ID: P83673

Aptamer ID	Aptamer descriptor	Target chemistry	Target name	Affinity	Binding Conditions/Buffer	PubMed ID
Apta_420	Undefined	Protein	LYS1_CRAVI	0.1 fM	50 mM NaCl, 10 mM Tris-HCL, 10 mM MgCl2, 1 mM dithiothreitol, pH 7.9	21826311

Aptamer Sequence:	AGGGACGGGCTAAGTAACTGTGGAGGGT
The optimal secondary structure in dot-bracket notation:	....((((.........)))).......
The centroid secondary structure in dot-bracket notation:	....((((.........)))).......

The MFE structure

The Centroid structure

The mountain plot representation

Type	Detail	Type	Detail
Aptamer ID	Apta_420	Description	Undefined
Aptamer chemistry	DNA	Length	28 nt
GC content	57.1%	Molecular weight	8,798.67 Da
Molarity of 1 μg/μl solution	113.65 μM	Number of G-quadruplexes	No QGRS found
G-Score	N/A	Function	Aptasensor
Sequence	AGGGACGGGCTAAGTAACTGTGGAGGGT
Applications	Detection of lysozyme

Type	Detail	Type	Detail
Uniprot ID	P83673	Protein name	Lysozyme 1 (EC 3.2.1.17) (1,4-beta-N-acetylmuramidase 1) (Invertebrate-type lysozyme 1) (cv-lysozyme 1)
Gene name(s)	lysoz1 lysoz	Organism	Lysozyme 1 (EC 3.2.1.17) (1,4-beta-N-acetylmuramidase 1) (Invertebrate-type lysozyme 1) (cv-lysozyme 1)
Status	reviewed in uniprot database	Length	184
Mass	19,986	Activity regulation	N/A
Involvement in disease	N/A	Catalytic activity	Reaction=Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins
PDB ID(s)	N/A
Function	Has antibacterial activity against the Gram-positive bacteria L.garvieae, M.luteus and Enterococcus sp.

No relevant experimental diagram	Interaction ID	426
	Target type	Protein
	Target unique ID	P83673
	Activity	0.1 fM
	Binding Conditions/Buffer	50 mM NaCl, 10 mM Tris-HCL, 10 mM MgCl2, 1 mM dithiothreitol, pH 7.9
	Assay	N/A
	PubMed ID	21826311

Aptamer ID	Aptamer chemistry	Sequence	Similarity
Apta_206	DNA	AGGAAGGGGTCTGAGATCTCGGAAT	60.71%
Apta_929	DNA	GAGTGGGATGGATAGAGAATAAGTGTGGAGTGGAAGGTGA	57.50%
Apta_14	DNA	AGCGGGGGGGGCTGGGCTGGGTGGG	57.14%
Apta_26	DNA	AGGGGGGGGGGTAAGGGTGGGTAGA	57.14%
Apta_207	DNA	AGGAAGGCTTTAGGTGGAAT	57.14%
Apta_678	DNA	CGTACGGTGGGAACGGTTCCTCTTAGGGT	55.17%
Apta_264	DNA	GGCGTTGTCGGGCGCAGGTGTAGGCCTCGTGGTGGTGGGT	55.00%
Apta_817	DNA	TGCGTGAGCGGTAGGCCCCTACGACCCACTGTGGTTGGGC	55.00%
Apta_947	DNA	CATGGCTAGGTGTTTATTAATCCTGTAGGATTTGCGGAAT	55.00%
Apta_1067	DNA	GCGCGGTACCGCGCTAACGGAGGTTGCGTCCGT	54.55%
Apta_564	DNA	GGGGACTGTTGTGGTATTATTTTTGGTTGTGCAGT	54.29%
Apta_1203	DNA	CCCTGCGGGGCTACCCGATATGTGTCCGAGTGGTG	54.29%
Apta_1206	DNA	GGCAGCAGCAATGTAACACTGTGTGTATGTGTTGG	54.29%
Apta_50	DNA	AGTGGCGAGGGGGGTAGGTAAAGTATCCTTAGTGTGTTG	53.85%
Apta_308	DNA	TGGCGGTACGGGCCGTGCACCCACTTACCTGGGAAGTGA	53.85%
Apta_13	DNA	AGGGGGGGGGGAGGGGTCGGGGTGG	53.57%
Apta_198	DNA	AGGAAGGCTTTAGGTCTGAG	53.57%
Apta_390	DNA	GGTGCGGCGGGACTAGTGGGTGTG	53.57%
Apta_483	DNA	ATTGGGAGGGATTGGGTGGG	53.57%
Apta_517	DNA	ACCTTCGGGGAGTATTGCGGAGGAAGGT	53.57%

ABOUT