AptaDB: Result

Interaction ID: 934

Aptamer sequence: CACCACGAUCACGGUUUCCCUCGCAGGUAAGGUGUAGA

Target unique ID: Other-1

Aptamer ID	Aptamer descriptor	Target chemistry	Target name	Affinity	Binding Conditions/Buffer	PubMed ID
Apta_848	Mitomer1	Other	Mitochondria	N/A	20mM Tris-HCl, 2mM KCl, 40mM NaCl, 1mM MgCl2, 250mM Sucrose, pH=7.5	25087963

Aptamer Sequence:	CACCACGAUCACGGUUUCCCUCGCAGGUAAGGUGUAGA
The optimal secondary structure in dot-bracket notation:	((((...(((.(((......)))..)))..))))....
The centroid secondary structure in dot-bracket notation:	((((..........................))))....

The MFE structure

The Centroid structure

The mountain plot representation

Type	Detail	Type	Detail
Aptamer ID	Apta_848	Description	Mitomer1
Aptamer chemistry	RNA	Length	38 nt
GC content	55.3%	Molecular weight	12,159.27 Da
Molarity of 1 μg/μl solution	82.24 μM	Number of G-quadruplexes	No QGRS found
G-Score	N/A	Function	Targeted binding
Sequence	CACCACGAUCACGGUUUCCCUCGCAGGUAAGGUGUAGA
Applications	Binding to mitochondria

Type	Detail	Type	Detail
Target ID	Other-1	Name	Mitochondria

	Interaction ID	934
	Target type	Other
	Target unique ID	Other-1
	Activity	N/A
	Binding Conditions/Buffer	20mM Tris-HCl, 2mM KCl, 40mM NaCl, 1mM MgCl2, 250mM Sucrose, pH=7.5
	Assay	Binding Affifinities of Truncated Mitomer2 (Short Mitomer2)
	PubMed ID	25087963

Aptamer ID	Aptamer chemistry	Sequence	Similarity
Apta_87	RNA	UACCGACUAGCAAAACCUGCUGGCGACGUUUAGAU	52.63%
Apta_315	RNA	GGGAGGACGAUGCGGUCGUAUUAUCCGCUGCACGCCAGACGACUCGCCCGA	50.98%
Apta_425	RNA	UGCCGCCAUAUCACACGGAUUUAAUCGCCGUAGAAAAGCAUGUCAAAGCCG	50.98%
Apta_426	RNA	UGCCGCUAUAAUGCACGGAUUUAAUCGCCGUAGAAAAGCAUGUCAAAGCCG	50.98%
Apta_1	RNA	ACGAAGCUUGAUCCCGUUUGCCGGUCGAUCGCUUCGA	50.00%
Apta_86	RNA	GAAACGACUCGACAACCUCGAGCGACGUGAAUCAU	50.00%
Apta_632	RNA	GACGAGAAGGAGUGCUGGUUAUACUAGCGGUUAGGUCACUCGUC	50.00%
Apta_658	RNA	CUGCGAUCAGGGGUAAAUUUCCGCGCAGGCUCCACGCCGC	50.00%
Apta_132	RNA	GGGAGGACGAUGCGGCGUUUCCUCUGGUUCGUCCCCAGACGACUCGCCCGA	49.02%
Apta_133	RNA	GGGAGGACGAUGCGGUGAGUCGUUCCCUUCGUCCCCAGACGACUCGCCCGA	49.02%
Apta_154	RNA	ACACGCGAGAUAGAGCGAGGCCUCCAAAAAUGGCCACGCCAGGAAGCAAGU	49.02%
Apta_424	RNA	UGCUAGUAUAUCGCACGGAUUUAAUCGCCGUAGAAAAGCAUGUCAAAGCCG	49.02%
Apta_849	RNA	UCCCGAUUACUGUACAUACCUUAGCCCAUAGCUGGCUGC	48.72%
Apta_90	RNA	ACAACCUAAAUGCGACGUUGGGUCAAAAACGUGAA	47.37%
Apta_93	RNA	CUCCGCUAUCUAACGUAUGAUAGAAUGGAUGACUA	47.37%
Apta_94	RNA	AUGACAGGAUGCAGAGCUCCACUGUCUAGUGUUUA	47.37%
Apta_152	RNA	UUACCACGCGCUCUUAACUGCUAGCGCCAUGGC	47.37%
Apta_230	RNA	GGGAGGACGAUGCGGGCGUGAAUGGUGUUGUGAGG	47.37%
Apta_319	RNA	ACCCUGAUGGUAGACGCCGGGGUG	47.37%
Apta_379	RNA	UACGACACGAUUGGGACGUGUCUAUGGGAC	47.37%

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