Aptamer-target interaction descriptor
Aptamer-target interaction information
| Aptamer ID | Aptamer descriptor | Target chemistry | Target name | Affinity | Binding Conditions/Buffer | PubMed ID |
|---|---|---|---|---|---|---|
| Apta_620 | N | Molecule | Mercuric cation | 40 nM | pH 7.0, 20 mM NaNO3, 8 mM Tris nitrate, 100 μM NaCN, 25 ℃ | 22936101 |
Structure information of aptamer
| Aptamer Sequence: | TTCTTTCTTCCCCTTGTTTGTT |
| The optimal secondary structure in dot-bracket notation: | ...................... |
| The centroid secondary structure in dot-bracket notation: | ...................... |
The MFE structure
The Centroid structure
The mountain plot representation
Aptamer information
| Type | Detail | Type | Detail |
|---|---|---|---|
| Aptamer ID | Apta_620 | Description | N |
| Aptamer chemistry | DNA | Length | 22 nt |
| GC content | 36.4% | Molecular weight | 6,590.24 Da |
| Molarity of 1 μg/μl solution | 151.74 μM | Number of G-quadruplexes | No QGRS found |
| G-Score | N/A | Function | Aptasensor |
| Sequence | TTCTTTCTTCCCCTTGTTTGTT | ||
| Applications | CPCH Aptasensor could screen a wide concentration range of heavy metal ions with high selectivity and reversibility | ||
Target information
| Type | Detail | Type | Detail |
|---|---|---|---|
| PubChem ID | 26623 | Molecular name | Mercuric cation |
| Molecular formula | Hg+2 | Molecular weight | 200.59 |
| IUPAC name | mercury(2+) | InChIKey | BQPIGGFYSBELGY-UHFFFAOYSA-N |
| LogP | -0.003 | Topological polar surface area | 0 |
| Hydrogen bond acceptor | 0 | Hydrogen bond donor | 0 |
Synonym(s): Mercuric cation; Mercuric ion; mercury(2+); Mercury, ion (Hg2+); Mercury (II) ion; Mercury ion (Hg2+); Hg2+; mercury(II); UNII-ED30FJ8Y42; 14302-87-5; Hg++; ED30FJ8Y42; Hg(2+); Mercury II; Mercury(2+) ions; Mercury (2+); mercury ion; Mercury dication; HgII; mercury (II); mercury(2+) ion; mercury(II) cation; Hg+2; DTXSID9074933; CHEBI:16793; MCULE-1248604119; NCGC00091572-02; NCGC00091572-03; C00703; Q26841278
Activity data
|
No relevant experimental diagram |
Interaction ID | 658 |
| Target type | Molecule | |
| Target unique ID | 26623 | |
| Activity | 40 nM | |
| Binding Conditions/Buffer | pH 7.0, 20 mM NaNO3, 8 mM Tris nitrate, 100 μM NaCN, 25 ℃ |
|
| Assay | N/A |
|
| PubMed ID | 22936101 |
Similar aptamers
| Aptamer ID | Aptamer chemistry | Sequence | Similarity |
|---|---|---|---|
| Apta_538 | DNA | GTGTTGTCTCTCTGTGTCTC | |
| Apta_541 | DNA | CACGTGTTGTCTCTCTGTGTCTCGTG | |
| Apta_1083 | DNA | TGCTGTTGTCACCTGCCTCGTCTCCCTCGT | |
| Apta_1149 | DNA | ATCATGGTGGGTATCGGCACTCGTTGGTTGAT | |
| Apta_216 | DNA | TGGTTGGTTTTTGGTTTTTTTTTTTGGTTT | |
| Apta_249 | DNA | CCCTGTTCCCCCTCCGCCGCTTGACTCTCC | |
| Apta_476 | DNA | CCTATCTTATTCGTTGCGGACTCCCCGGTCGGTATGTATG | |
| Apta_540 | DNA | ACGTGTTGTCTCTCTGTGTCTCGT | |
| Apta_542 | DNA | GCACGTGTTGTCTCTCTGTGTCTCGTGC | |
| Apta_914 | DNA | CGCTCCGTTTACTCGGTCTGCTATTGGCTTGCCTTTGTTT | |
| Apta_1155 | DNA | TAGTTTTATTTGTTCATTTTGTGTATTGTTTTGA | |
| Apta_1238 | DNA | GGTTTTGTGTTTGTGTTTTGTGGTTGTTGT | |
| Apta_253 | DNA | CCCTGTTCGCTATCCCCCATCCCCCGATTGC | |
| Apta_477 | DNA | CGCGGAAGAATTGCTATGTGTGCCCCGGTTGGTCTGTATA | |
| Apta_1263 | DNA | CCCCGCTGCCCGTGTTCCGTCCTCCCTTGCTGTGTGTGCG | |
| Apta_1036 | DNA | ATACCAGTCTATTCAATTGGGCCCGTCCGTATGGTGGG | |
| Apta_240 | DNA | TTTTTAATTAAAGCTCGCCATCAAATAGCTTT | |
| Apta_543 | DNA | GGCACGTGTTGTCTCTCTGTGTCTCGTGCC | |
| Apta_917 | DNA | TCGATTTCCTTAGTTGTCTTCCTTAGTGAG | |
| Apta_1084 | DNA | TTCCCTCCTCTGTTGTTCCCCCCTCCTCTC |
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