AptaDB: Result

Interaction ID: 833

Aptamer sequence: GGTCGCAGATGGATTAAGTATGTGGGTGGGGGGGTGGAAGTTAAT

Target unique ID: CRM-CCL-185

Aptamer ID	Aptamer descriptor	Target chemistry	Target name	Affinity	Binding Conditions/Buffer	PubMed ID
Apta_751	S11.f	Cell	vaccinia virus–infected and–uninfected lung cancer A549 cells	43.1 nM	5 mmol MgCl2 and 4.5 g glucose into 1 L of Dulbecco's PBS without calcium and magnesium	19684903

Aptamer Sequence:	GGTCGCAGATGGATTAAGTATGTGGGTGGGGGGGTGGAAGTTAAT
The optimal secondary structure in dot-bracket notation:	..(((((.............)))))....................
The centroid secondary structure in dot-bracket notation:	...((((.............)))).....................

The MFE structure

The Centroid structure

The mountain plot representation

Type	Detail	Type	Detail
Aptamer ID	Apta_751	Description	S11.f
Aptamer chemistry	DNA	Length	45 nt
GC content	51.1%	Molecular weight	14,212.11 Da
Molarity of 1 μg/μl solution	70.36 μM	Number of G-quadruplexes	2
G-Score	21	Function	Target recognition
Sequence	GGTCGCAGATGGATTAAGTATGTGGGTGGGGGGGTGGAAGTTAAT
Applications	Recognition of subtype non-small cell lung cancer

Type	Detail	Type	Detail
ATCC ID	CRM-CCL-185	Cell name	vaccinia virus-infected and-uninfected lung cancer A549 cells
Category	Human cells	Organism	Homo sapiens, human
Product type	Certified reference material	Cell type	epithelial cell
Morphology	epithelial	Tissue	Lung
Disease	Carcinoma	Product format	Frozen
Antigen expression	N/A	Genes expressed	N/A
Cell description	N/A
Application(s)	Assay development

No relevant experimental diagram	Interaction ID	833
	Target type	Cell
	Target unique ID	CRM-CCL-185
	Activity	43.1 nM
	Binding Conditions/Buffer	5 mmol MgCl2 and 4.5 g glucose into 1 L of Dulbecco's PBS without calcium and magnesium
	Assay	N/A
	PubMed ID	19684903

Aptamer ID	Aptamer chemistry	Sequence	Similarity
Apta_929	DNA	GAGTGGGATGGATAGAGAATAAGTGTGGAGTGGAAGGTGA	62.22%
Apta_1255	DNA	GGCGCATGATCATTCGGTGGGTAAGGTGGTGGTAACGTTG	62.22%
Apta_46	DNA	CGGGTGGGAGTTGTGGGGGGGGGTGGGAGGGTT	60.00%
Apta_266	DNA	TGGATGGTAGCTCGGTCGGGGTGGGTGGGTTGGCAAGTCT	57.78%
Apta_862	DNA	TGTGCCAAAGAGAGTGGTGGGGGGGTGGGCGGAACTCGCG	57.78%
Apta_1205	DNA	GGCAGGTGGTGTTGGTTGGTTGTGCGTGGAGTTGG	57.78%
Apta_41	DNA	CGGTCGCTCCGTGTGGCTTGGGTTGGGTGTGGCAGTGAC	55.56%
Apta_267	DNA	GAGTGCGTAATGGTACGATTTGGGAAGTGGCTTGGGGTGG	55.56%
Apta_463	DNA	GTTCTCATGCACACTTATAGCGGGGGGATCCAGTACT	55.56%
Apta_646	DNA	TGGAGCTTGGATTGATGTGGTGTGTGAGTGCGGTGCCC	55.56%
Apta_782	DNA	AGGTGTGACTCGATCTGTGGGGGTTGGGGGGTGGTTTTTCGGAA	55.56%
Apta_820	DNA	TCCCACGATCTCATTAGTCTGTGGATAAGCGTGGGACGTCTATGA	55.56%
Apta_464	DNA	GTCAGATTCCACTATAGTAGGTTGGGTAGGGTGGTCGCAGTGGATGATATGTCGTAGGGG	55.00%
Apta_570	DNA	GGCAAGATGTGCCCAGAACAGTTGCTTGTATGGTGGGGAGCGTCCATATTGGCTTAAAC	54.24%
Apta_650	DNA	GCACACCGATGGCGGTCCTGTTTAGGGGGTGTGCGTGGGGAGGTGCGGTTGC	53.85%
Apta_753	DNA	GGGCACAGACGGAAGATGAGAATTGTGGGGCTTAGTATAGTGAGGTGCGTGT	53.85%
Apta_72	DNA	AGTCAGTAGGTTGGTGTGGTTGGGGCTGACT	53.33%
Apta_76	DNA	CAGCGCTAGGGCTTTTAGCGTAATGGGTAGGGTGGTGCGGTGCAGATATCGGAATTGGTG	53.33%
Apta_77	DNA	GGTGTGGGCGACATGGGGGTTGGTGGTGTAGGAGCGCCAT	53.33%
Apta_180	DNA	GGTCCCCCGTAAATTGAGAATTTGGGCGTTTTGGTTCTA	53.33%

ABOUT