Aptamer-target interaction descriptor
Aptamer-target interaction information
| Aptamer ID | Aptamer descriptor | Target chemistry | Target name | Affinity | Binding Conditions/Buffer | PubMed ID |
|---|---|---|---|---|---|---|
| Apta_1203 | Aptamer 5 | Cell | Mycobacterium tuberculosis subsp. Tuberculosis | 96 nM | 20 mmol/L HEPES buffer at pH 7.35, 1 mmol/L MgCl2, 120 mmol/L NaCl, 1 mmol/L CaCl2, and 5 mmol/L KCl | 28689112 |
Structure information of aptamer
| Aptamer Sequence: | CCCTGCGGGGCTACCCGATATGTGTCCGAGTGGTG |
| The optimal secondary structure in dot-bracket notation: | (((....)))((((.((.........)).)))).. |
| The centroid secondary structure in dot-bracket notation: | ..........((((.(...........).)))).. |
The MFE structure
The Centroid structure
The mountain plot representation
Aptamer information
| Type | Detail | Type | Detail |
|---|---|---|---|
| Aptamer ID | Apta_1203 | Description | Aptamer 5 |
| Aptamer chemistry | DNA | Length | 35 nt |
| GC content | 65.7% | Molecular weight | 10,795.90 Da |
| Molarity of 1 μg/μl solution | 92.63 μM | Number of G-quadruplexes | No QGRS found |
| G-Score | N/A | Function | Target detection |
| Sequence | CCCTGCGGGGCTACCCGATATGTGTCCGAGTGGTG | ||
| Applications | Detection of H37Rv in clinical diagnosis | ||
Target information
| Type | Detail | Type | Detail |
|---|---|---|---|
| ATCC ID | 27294 | Cell name | Mycobacterium tuberculosis subsp. Tuberculosis |
| Category | Bacteria | Organism | N/A |
| Product type | N/A | Cell type | N/A |
| Morphology | N/A | Tissue | N/A |
| Disease | N/A | Product format | Frozen |
| Antigen expression | N/A | Genes expressed | N/A |
| Cell description | This strain has been assigned to Risk Group 3-agents associated with serious or lethal human disease for which preventive or therapeutic interventions may be available. |
|
|
| Application(s) | N/A | ||
Activity data
|
No relevant experimental diagram |
Interaction ID | 1265 |
| Target type | Cell | |
| Target unique ID | 27294 | |
| Activity | 96 nM | |
| Binding Conditions/Buffer | 20 mmol/L HEPES buffer at pH 7.35, 1 mmol/L MgCl2, 120 mmol/L NaCl, 1 mmol/L CaCl2, and 5 mmol/L KCl |
|
| Assay | N/A |
|
| PubMed ID | 28689112 |
Similar aptamers
| Aptamer ID | Aptamer chemistry | Sequence | Similarity |
|---|---|---|---|
| Apta_1199 | DNA | CCCTGCGGGGCTGCCCGATATGTGTCCAAGTGGTG | |
| Apta_1199 | DNA | CCCTGCGGGGCTGCCCGATATGTGTCCAAGTGGTG | |
| Apta_1199 | DNA | CCCTGCGGGGCTGCCCGATATGTGTCCAAGTGGTG | |
| Apta_1199 | DNA | CCCTGCGGGGCTGCCCGATATGTGTCCAAGTGGTG | |
| Apta_1208 | DNA | CCCTGCGGGGCTGCCCGATATGTGTCCAGGTGGTG | |
| Apta_692 | DNA | ACGTTGACGCTGGTGCCCGCTTGTGGTGCGAGTGTTGTGT | |
| Apta_1262 | DNA | ACAAGGGGTGCAGGGGTCCGCGATTGTGACTGTGTGTGCG | |
| Apta_515 | DNA | CCTGGGGGAGTATTGCGGAGGAAGG | |
| Apta_517 | DNA | ACCTTCGGGGAGTATTGCGGAGGAAGGT | |
| Apta_630 | DNA | GACCAGGGCAAACGGTAGGGAGTGGTC | |
| Apta_1059 | DNA | TCGTGACGCCGTGCAGTTACCGATACGAGCCTCGTTTTG | |
| Apta_552 | DNA | CACCTGGGGGAGTATTGCGGAGGAAGGTTCCAGGTG | |
| Apta_57 | DNA | GCGGGTCGGTTGCTCGCTTCGCCCGATCGGTCTAAGGGTG | |
| Apta_148 | DNA | CCGTAGGTTCGGGGTCGGAGTGGTCCGGAAGGTGGCGTGG | |
| Apta_149 | DNA | CCGTAGGTTCGGGGTCGGAGTGGTCCGGAAGATGGCGTGG | |
| Apta_258 | DNA | CACTGCGGGGGTCTATACGTGAGGAAGAAGTGGGCAGGTC | |
| Apta_507 | DNA | GGCGGGGCTACGAAGTAGTGATTTTTTCCGATGGCCCGTG | |
| Apta_578 | DNA | CACCAAGCGCAGGGAATTACATTGAAGTGTGGGATTGGCT | |
| Apta_831 | DNA | CCGCCCAGCGGGGGTAGGGCCGGACGTAGGAGGAGCTGCG | |
| Apta_873 | DNA | CCACCGAGCCTACCACATGTGACATCCCAGGACATAGCTG |
DEV TOOL
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