AptaDB: Result

Interaction ID: 1267

Aptamer sequence: GGCAGGTGGTGTTGGTTGGTTGTGCGTGGAGTTGG

Target unique ID: 27294

Aptamer ID	Aptamer descriptor	Target chemistry	Target name	Affinity	Binding Conditions/Buffer	PubMed ID
Apta_1205	Aptamer 7	Cell	Mycobacterium tuberculosis subsp. Tuberculosis	107 nM	20 mmol/L HEPES buffer at pH 7.35, 1 mmol/L MgCl2, 120 mmol/L NaCl, 1 mmol/L CaCl2, and 5 mmol/L KCl	28689112

Aptamer Sequence:	GGCAGGTGGTGTTGGTTGGTTGTGCGTGGAGTTGG
The optimal secondary structure in dot-bracket notation:	..((.(((..............))).)).......
The centroid secondary structure in dot-bracket notation:	...................................

The MFE structure

The Centroid structure

The mountain plot representation

Type	Detail	Type	Detail
Aptamer ID	Apta_1205	Description	Aptamer 7
Aptamer chemistry	DNA	Length	35 nt
GC content	60.0%	Molecular weight	11,048.04 Da
Molarity of 1 μg/μl solution	90.51 μM	Number of G-quadruplexes	No QGRS found
G-Score	N/A	Function	Target detection
Sequence	GGCAGGTGGTGTTGGTTGGTTGTGCGTGGAGTTGG
Applications	Detection of H37Rv in clinical diagnosis

Type	Detail	Type	Detail
ATCC ID	27294	Cell name	Mycobacterium tuberculosis subsp. Tuberculosis
Category	Bacteria	Organism	N/A
Product type	N/A	Cell type	N/A
Morphology	N/A	Tissue	N/A
Disease	N/A	Product format	Frozen
Antigen expression	N/A	Genes expressed	N/A
Cell description	This strain has been assigned to Risk Group 3-agents associated with serious or lethal human disease for which preventive or therapeutic interventions may be available.
Application(s)	N/A

No relevant experimental diagram	Interaction ID	1267
	Target type	Cell
	Target unique ID	27294
	Activity	107 nM
	Binding Conditions/Buffer	20 mmol/L HEPES buffer at pH 7.35, 1 mmol/L MgCl2, 120 mmol/L NaCl, 1 mmol/L CaCl2, and 5 mmol/L KCl
	Assay	N/A
	PubMed ID	28689112

Aptamer ID	Aptamer chemistry	Sequence	Similarity
Apta_482	DNA	AGCAAGGTTTGGTGTTGGTTGGTTGCTGGTTTTGGTTTC	69.23%
Apta_350	DNA	GGTGGTGGTGGTTGTGGTGGTGGTGG	68.57%
Apta_757	DNA	GGTGGTGGTGGTTGTGGTGGTGG	65.71%
Apta_1210	DNA	GGGGAGGCAGTGTGTTGTGTCGTGTGTGTGCTTGG	65.71%
Apta_1247	DNA	GGTGGTTGCTGTTGTTTGTGGTTGGTGTGC	65.71%
Apta_1092	DNA	CCCATGGTAGGTATTGCTTGGTAGGGATAGTGGGCTTGATG	63.41%
Apta_10	DNA	GGGGGGGGTGGCTGGGCGGGGTGGG	62.86%
Apta_12	DNA	TGAGGGGGTGGGTGGGACGGGTTGG	62.86%
Apta_74	DNA	GGACAGTAGGTTGGTGTGGTTGGGGCTGTCC	62.86%
Apta_75	DNA	CACTGGTAGGTTGGTGTGGTTGGGGCCAGTG	62.86%
Apta_124	DNA	GGTGGTGGGGGGGGTTGGTAGGGTGTCTTC	62.86%
Apta_679	DNA	CAGGTGGCAGATCGGGTGTGGGTGGCCTGG	62.86%
Apta_1237	DNA	GGGGTTGTGTGGGGAGTTTGTCCTGTTGTG	62.86%
Apta_1240	DNA	GGAGTAGTGGGGATTGTGGTGTATGTTGTC	62.86%
Apta_857	DNA	GCTATGGGTGGTCTGGTTGGGATTGGCCCCGGGAGCTGGC	62.50%
Apta_1091	DNA	CCATGGTAGGTATTGCTTGGTAGGGATAGTGGGCTTGATG	62.50%
Apta_41	DNA	CGGTCGCTCCGTGTGGCTTGGGTTGGGTGTGGCAGTGAC	61.54%
Apta_1026	DNA	GGGGGGTGTATCGTTGACGAGTTGCGCGTGCGTCTCGTG	61.54%
Apta_14	DNA	AGCGGGGGGGGCTGGGCTGGGTGGG	60.00%
Apta_25	DNA	TGTGGGGGTGGTTGGGCGGGGCTGC	60.00%

ABOUT