AptaDB: Result

Interaction ID: 1218

Aptamer sequence: CCAGTACAAGGTGCTAAACGTAAT

Target unique ID: P14151

Aptamer ID	Aptamer descriptor	Target chemistry	Target name	Affinity	Binding Conditions/Buffer	PubMed ID
Apta_1158	LS Primer	Protein	LYAM1_HUMAN	N/A	N/A	25826688

Aptamer Sequence:	CCAGTACAAGGTGCTAAACGTAAT
The optimal secondary structure in dot-bracket notation:	..(((((...))))).........
The centroid secondary structure in dot-bracket notation:	..(((((...))))).........

The MFE structure

The Centroid structure

The mountain plot representation

Type	Detail	Type	Detail
Aptamer ID	Apta_1158	Description	LS Primer
Aptamer chemistry	DNA	Length	24 nt
GC content	41.7%	Molecular weight	7,369.80 Da
Molarity of 1 μg/μl solution	135.69 μM	Number of G-quadruplexes	No QGRS found
G-Score	N/A	Function	Targeted therapy
Sequence	CCAGTACAAGGTGCTAAACGTAAT
Applications	Inhibit L-selectin

Type	Detail	Type	Detail
Uniprot ID	P14151	Protein name	L-selectin (CD62 antigen-like family member L) (Leukocyte adhesion molecule 1) (LAM-1) (Leukocyte surface antigen Leu-8) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (Lymph node homing receptor) (TQ1) (gp90-MEL) (CD antigen CD62L)
Gene name(s)	SELL LNHR LYAM1	Organism	L-selectin (CD62 antigen-like family member L) (Leukocyte adhesion molecule 1) (LAM-1) (Leukocyte surface antigen Leu-8) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (Lymph node homing receptor) (TQ1) (gp90-MEL) (CD antigen CD62L)
Status	reviewed in uniprot database	Length	372
Mass	42,187	Activity regulation	N/A
Involvement in disease	N/A	Catalytic activity	N/A
PDB ID(s)	2LGF;3CFW;5VC1;
Function	Calcium-dependent lectin that mediates cell adhesion by binding to glycoproteins on neighboring cells.

No relevant experimental diagram	Interaction ID	1218
	Target type	Protein
	Target unique ID	P14151
	Activity	N/A
	Binding Conditions/Buffer	N/A
	Assay	N/A
	PubMed ID	25826688

Aptamer ID	Aptamer chemistry	Sequence	Similarity
Apta_306	DNA	CAAGGTAACCAGTACAAGGTGCTAAACGTAATGGCTTCG	61.54%
Apta_1024	DNA	GTCCAGGGTTCCAAGGTGCTTCGTGGAC	57.14%
Apta_326	DNA	GCAACAGGGTATCCAAAGGATCAAA	56.00%
Apta_683	DNA	GCAGTACGATCGGGGGTGGGTGGATGTAGG	53.33%
Apta_185	DNA	ACCAAGGCTTTAGGTCTGAGATCTCCCAAT	50.00%
Apta_199	DNA	TAGGTCTGAGATCTCGGAAT	50.00%
Apta_201	DNA	CTGAGATCTCGGAAT	50.00%
Apta_207	DNA	AGGAAGGCTTTAGGTGGAAT	50.00%
Apta_208	DNA	AGGAAGGGGTGGAAT	50.00%
Apta_345	DNA	ACAGTAACCGCGTGAGGTCGA	50.00%
Apta_373	RNA	CCAUACGGGAGAGAAACU	50.00%
Apta_419	DNA	ATCAGGGCTAAAGAGTGCAGAGTTACTTAG	50.00%
Apta_682	DNA	CCTTGTAGATCGGGTGTGGTTTGGCGTAGG	50.00%
Apta_873	DNA	CCACCGAGCCTACCACATGTGACATCCCAGGACATAGCTG	50.00%
Apta_939	DNA	TTGCCCACCGTACTGTGCAGGTCGAACTACAGGCACGTCGTG	50.00%
Apta_309	DNA	TAGCCAAGGTAACCAGTACAAGGTGCTAAACGTAATGGCTTCGGCTTAC	48.98%
Apta_309	DNA	TAGCCAAGGTAACCAGTACAAGGTGCTAAACGTAATGGCTTCGGCTTAC	48.98%
Apta_159	DNA	GCGTGCAGCATGACCACCGATGTCACACTTAATGAGAAT	48.72%
Apta_162	DNA	CCGTACATACTACGTACGTACGTGAACAGAGGCAGAG	48.65%
Apta_193	DNA	AGGAAGGCTTTAGGGTCTGAGATCTCGGAAT	48.39%

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