Aptamer-target interaction descriptor
Aptamer-target interaction information
| Aptamer ID | Aptamer descriptor | Target chemistry | Target name | Affinity | Binding Conditions/Buffer | PubMed ID |
|---|---|---|---|---|---|---|
| Apta_1210 | Aptamer 12 | Cell | Mycobacterium tuberculosis subsp. Tuberculosis | 110 nM | 20 mmol/L HEPES buffer at pH 7.35, 1 mmol/L MgCl2, 120 mmol/L NaCl, 1 mmol/L CaCl2, and 5 mmol/L KCl | 28689112 |
Structure information of aptamer
| Aptamer Sequence: | GGGGAGGCAGTGTGTTGTGTCGTGTGTGTGCTTGG |
| The optimal secondary structure in dot-bracket notation: | ...((.((((....)))).)).............. |
| The centroid secondary structure in dot-bracket notation: | ...((.(((......))).)).............. |
The MFE structure
The Centroid structure
The mountain plot representation
Aptamer information
| Type | Detail | Type | Detail |
|---|---|---|---|
| Aptamer ID | Apta_1210 | Description | Aptamer 12 |
| Aptamer chemistry | DNA | Length | 35 nt |
| GC content | 60.0% | Molecular weight | 11,008.02 Da |
| Molarity of 1 μg/μl solution | 90.84 μM | Number of G-quadruplexes | No QGRS found |
| G-Score | N/A | Function | Target detection |
| Sequence | GGGGAGGCAGTGTGTTGTGTCGTGTGTGTGCTTGG | ||
| Applications | Detection of H37Rv in clinical diagnosis | ||
Target information
| Type | Detail | Type | Detail |
|---|---|---|---|
| ATCC ID | 27294 | Cell name | Mycobacterium tuberculosis subsp. Tuberculosis |
| Category | Bacteria | Organism | N/A |
| Product type | N/A | Cell type | N/A |
| Morphology | N/A | Tissue | N/A |
| Disease | N/A | Product format | Frozen |
| Antigen expression | N/A | Genes expressed | N/A |
| Cell description | This strain has been assigned to Risk Group 3-agents associated with serious or lethal human disease for which preventive or therapeutic interventions may be available. |
|
|
| Application(s) | N/A | ||
Activity data
|
No relevant experimental diagram |
Interaction ID | 1272 |
| Target type | Cell | |
| Target unique ID | 27294 | |
| Activity | 110 nM | |
| Binding Conditions/Buffer | 20 mmol/L HEPES buffer at pH 7.35, 1 mmol/L MgCl2, 120 mmol/L NaCl, 1 mmol/L CaCl2, and 5 mmol/L KCl |
|
| Assay | N/A |
|
| PubMed ID | 28689112 |
Similar aptamers
| Aptamer ID | Aptamer chemistry | Sequence | Similarity |
|---|---|---|---|
| Apta_1241 | DNA | GGTGTGGAGTGGTGTGTGTTGTTGTTTGTC | |
| Apta_350 | DNA | GGTGGTGGTGGTTGTGGTGGTGGTGG | |
| Apta_1205 | DNA | GGCAGGTGGTGTTGGTTGGTTGTGCGTGGAGTTGG | |
| Apta_1244 | DNA | GGAGATGTCAGTTGTGTGTGTGGTTATGGC | |
| Apta_1247 | DNA | GGTGGTTGCTGTTGTTTGTGGTTGGTGTGC | |
| Apta_10 | DNA | GGGGGGGGTGGCTGGGCGGGGTGGG | |
| Apta_71 | DNA | GGCGAGTAGGTTGGTGTGGTTGGGGCTCGCC | |
| Apta_73 | DNA | GGGGAGTAGGTTGGTGTGGTTGGGGCTCCCC | |
| Apta_124 | DNA | GGTGGTGGGGGGGGTTGGTAGGGTGTCTTC | |
| Apta_679 | DNA | CAGGTGGCAGATCGGGTGTGGGTGGCCTGG | |
| Apta_1206 | DNA | GGCAGCAGCAATGTAACACTGTGTGTATGTGTTGG | |
| Apta_1245 | DNA | AGTGTGAAGTGGTGTGTGTTGTTGTTTGTC | |
| Apta_1246 | DNA | GGAGATGTATGAGCGGGTGTTTGTGTTTGC | |
| Apta_69 | DNA | AGCGAGTAGGTTGGTGTGGTTGGGGCTCGCT | |
| Apta_74 | DNA | GGACAGTAGGTTGGTGTGGTTGGGGCTGTCC | |
| Apta_203 | DNA | GGAAGGCTTTAGGTCTGAGATCTCGG | |
| Apta_757 | DNA | GGTGGTGGTGGTTGTGGTGGTGG | |
| Apta_928 | DNA | GATTGAGTAGATAGTGGTTCTGTACGTAGTGAAAGAGTGG | |
| Apta_1085 | DNA | TGGGGTGGTGGTGTGGGTGGGGGTTTGTTC | |
| Apta_1238 | DNA | GGTTTTGTGTTTGTGTTTTGTGGTTGTTGT |
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