Aptamer-target interaction descriptor
Aptamer-target interaction information
| Aptamer ID | Aptamer descriptor | Target chemistry | Target name | Affinity | Binding Conditions/Buffer | PubMed ID |
|---|---|---|---|---|---|---|
| Apta_1206 | Aptamer 8 | Cell | Mycobacterium tuberculosis subsp. Tuberculosis | 102 nM | 20 mmol/L HEPES buffer at pH 7.35, 1 mmol/L MgCl2, 120 mmol/L NaCl, 1 mmol/L CaCl2, and 5 mmol/L KCl | 28689112 |
Structure information of aptamer
| Aptamer Sequence: | GGCAGCAGCAATGTAACACTGTGTGTATGTGTTGG |
| The optimal secondary structure in dot-bracket notation: | .....(((((.((((.(((...)))))))))))). |
| The centroid secondary structure in dot-bracket notation: | .....((((..(((..(((...))).))).)))). |
The MFE structure
The Centroid structure
The mountain plot representation
Aptamer information
| Type | Detail | Type | Detail |
|---|---|---|---|
| Aptamer ID | Apta_1206 | Description | Aptamer 8 |
| Aptamer chemistry | DNA | Length | 35 nt |
| GC content | 48.6% | Molecular weight | 10,882.00 Da |
| Molarity of 1 μg/μl solution | 91.89 μM | Number of G-quadruplexes | No QGRS found |
| G-Score | N/A | Function | Target detection |
| Sequence | GGCAGCAGCAATGTAACACTGTGTGTATGTGTTGG | ||
| Applications | Detection of H37Rv in clinical diagnosis | ||
Target information
| Type | Detail | Type | Detail |
|---|---|---|---|
| ATCC ID | 27294 | Cell name | Mycobacterium tuberculosis subsp. Tuberculosis |
| Category | Bacteria | Organism | N/A |
| Product type | N/A | Cell type | N/A |
| Morphology | N/A | Tissue | N/A |
| Disease | N/A | Product format | Frozen |
| Antigen expression | N/A | Genes expressed | N/A |
| Cell description | This strain has been assigned to Risk Group 3-agents associated with serious or lethal human disease for which preventive or therapeutic interventions may be available. |
|
|
| Application(s) | N/A | ||
Activity data
|
No relevant experimental diagram |
Interaction ID | 1268 |
| Target type | Cell | |
| Target unique ID | 27294 | |
| Activity | 102 nM | |
| Binding Conditions/Buffer | 20 mmol/L HEPES buffer at pH 7.35, 1 mmol/L MgCl2, 120 mmol/L NaCl, 1 mmol/L CaCl2, and 5 mmol/L KCl |
|
| Assay | N/A |
|
| PubMed ID | 28689112 |
Similar aptamers
| Aptamer ID | Aptamer chemistry | Sequence | Similarity |
|---|---|---|---|
| Apta_1200 | DNA | GGCACACAGGACTATACAGTGTTGCAGTGTTGCTG | |
| Apta_1210 | DNA | GGGGAGGCAGTGTGTTGTGTCGTGTGTGTGCTTGG | |
| Apta_1246 | DNA | GGAGATGTATGAGCGGGTGTTTGTGTTTGC | |
| Apta_1261 | DNA | GGGCGGACGCTAGGTGGTGATGCTGTGCTACACGTGTTGT | |
| Apta_834 | DNA | CGCAATACCAAAGTGGCGAGAGCGCTGTCTTGAGTGAGTGGTTGG | |
| Apta_58 | DNA | GCACCTTGATGACATGATAGTCGTTGTGTATGCAGTTGGC | |
| Apta_542 | DNA | GCACGTGTTGTCTCTCTGTGTCTCGTGC | |
| Apta_543 | DNA | GGCACGTGTTGTCTCTCTGTGTCTCGTGCC | |
| Apta_673 | DNA | GCAGTCCTAGATCGGGTGTGGCTGGCTTGG | |
| Apta_781 | DNA | GTACGCCGCAAGACGAGTTGTGTATAAGCCGGC | |
| Apta_1150 | DNA | CTAAGCAGGAAGGTATGGATTGGTTGCATTAG | |
| Apta_1240 | DNA | GGAGTAGTGGGGATTGTGGTGTATGTTGTC | |
| Apta_1242 | DNA | GGAGCGATTAGTAGTGGTCTTGTCTTTTGC | |
| Apta_1244 | DNA | GGAGATGTCAGTTGTGTGTGTGGTTATGGC | |
| Apta_1287 | DNA | GCCCGCATGCCGTCAAGCAATGTTAATCTTGTTTTGATTTCG | |
| Apta_257 | DNA | GGCAGAAGAAATATCGAAACCCAGAATGGTCGGCCAGGCG | |
| Apta_875 | DNA | GCCGCGACCATACAACGCAAACAACACGCCTGTACGCTTG | |
| Apta_1216 | DNA | AGCGTCCTCTGCATAGTGATTTACGCTATGTGTACAGTGC | |
| Apta_1259 | DNA | GGCGCGGCATGGTGTGGACTCCAGGCGGTAGGGATGTCGT | |
| Apta_324 | DNA | CAAACAATCAAACAGCAGTGGGGTG |
DEV TOOL
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