Aptamer-target interaction descriptor
Aptamer-target interaction information
| Aptamer ID | Aptamer descriptor | Target chemistry | Target name | Affinity | Binding Conditions/Buffer | PubMed ID |
|---|---|---|---|---|---|---|
| Apta_1094 | aptamer | Molecule | Perfluorohexanesulfonic acid | 3.3 μM | 20 mM HEPES, 1 M NaCl, 10 mM MgCl2, and 5 mM KCl | 34991260 |
Structure information of aptamer
| Aptamer Sequence: | GGAATCGTGGGTGGTAGGGTAGGGGATGCA |
| The optimal secondary structure in dot-bracket notation: | ...(((.((.....)).))).......... |
| The centroid secondary structure in dot-bracket notation: | .....(.(.......).)............ |
The MFE structure
The Centroid structure
The mountain plot representation
Aptamer information
| Type | Detail | Type | Detail |
|---|---|---|---|
| Aptamer ID | Apta_1094 | Description | aptamer |
| Aptamer chemistry | DNA | Length | 30 nt |
| GC content | 60.0% | Molecular weight | 9,488.09 Da |
| Molarity of 1 μg/μl solution | 105.40 μM | Number of G-quadruplexes | 2 |
| G-Score | 20 | Function | Aptasensor |
| Sequence | GGAATCGTGGGTGGTAGGGTAGGGGATGCA | ||
| Applications | Fluorescence sensor for perfluorooctanoic acid、perfluoroheptanoic acid、perfluorohexanesulfonic acid detection in water | ||
Target information
| Type | Detail | Type | Detail |
|---|---|---|---|
| PubChem ID | 67734 | Molecular name | Perfluorohexanesulfonic acid |
| Molecular formula | C6HF13O3S | Molecular weight | 400.12 |
| IUPAC name | 1,1,2,2,3,3,4,4,5,5,6,6,6-tridecafluorohexane-1-sulfonic acid | InChIKey | QZHDEAJFRJCDMF-UHFFFAOYSA-N |
| LogP | 3.571 | Topological polar surface area | 54.37 |
| Hydrogen bond acceptor | 2 | Hydrogen bond donor | 1 |
Synonym(s): Perfluorohexanesulfonic acid; 355-46-4; 1,1,2,2,3,3,4,4,5,5,6,6,6-Tridecafluorohexane-1-sulfonic acid; Perfluorohexane-1-sulphonic acid; PFHxS; perfluorohexane sulfonic acid; UNII-ZU6Y1E592S; 1-Hexanesulfonic acid, 1,1,2,2,3,3,4,4,5,5,6,6,6-tridecafluoro-; tridecafluorohexane-1-sulfonic acid; perfluorohexanesulphonic acid; ZU6Y1E592S; Perfluorohexane-1-sulfonic acid; DTXSID7040150; C6HF13O3S; EINECS 206-587-1; Perfluorohexane sulfonic acid (PFHxS); SCHEMBL332726; CHEMBL1906987; HSDB 8274; AMY7161; CHEBI:132448; CS-B0907; 4434AB; MFCD00042453; ZINC38141431; AKOS016005064; LS41238; Q26833878; Perfluorohexanesulfonic acid 100 microg/mL in Acetonitrile; Perfluorohexanesulfonic acid 50 microg/mL in Methanol:Water
Activity data
|
No relevant experimental diagram |
Interaction ID | 1148 |
| Target type | Molecule | |
| Target unique ID | 9554 | |
| Activity | 5.5 μM | |
| Binding Conditions/Buffer | 20 mM HEPES, 1 M NaCl, 10 mM MgCl2, and 5 mM KCl |
|
| Assay | N/A |
|
| PubMed ID | 34991260 | |
|
No relevant experimental diagram |
Interaction ID | 1149 |
| Target type | Molecule | |
| Target unique ID | 67818 | |
| Activity | 6.5 μM | |
| Binding Conditions/Buffer | 20 mM HEPES, 1 M NaCl, 10 mM MgCl2, and 5 mM KCl |
|
| Assay | N/A |
|
| PubMed ID | 34991260 | |
|
No relevant experimental diagram |
Interaction ID | 1150 |
| Target type | Molecule | |
| Target unique ID | 67734 | |
| Activity | 3.3 μM | |
| Binding Conditions/Buffer | 20 mM HEPES, 1 M NaCl, 10 mM MgCl2, and 5 mM KCl |
|
| Assay | N/A |
|
| PubMed ID | 34991260 |
Similar aptamers
| Aptamer ID | Aptamer chemistry | Sequence | Similarity |
|---|---|---|---|
| Apta_25 | DNA | TGTGGGGGTGGTTGGGCGGGGCTGC | |
| Apta_74 | DNA | GGACAGTAGGTTGGTGTGGTTGGGGCTGTCC | |
| Apta_15 | DNA | TGAGGGGGGGGGAGGGCGGGGCTGC | |
| Apta_21 | DNA | TGTGGGGGAGGACGGGCGGGGATGC | |
| Apta_350 | DNA | GGTGGTGGTGGTTGTGGTGGTGGTGG | |
| Apta_669 | DNA | AACGTGGGAGGGCGGTGGTGTTGAA | |
| Apta_71 | DNA | GGCGAGTAGGTTGGTGTGGTTGGGGCTCGCC | |
| Apta_72 | DNA | AGTCAGTAGGTTGGTGTGGTTGGGGCTGACT | |
| Apta_1256 | DNA | GATCGGGTGTGGGTGGCGTAAAGGGAGCATCGGACA | |
| Apta_8 | DNA | TGTGGGGGTGGACGGGCCGGGTAGA | |
| Apta_10 | DNA | GGGGGGGGTGGCTGGGCGGGGTGGG | |
| Apta_12 | DNA | TGAGGGGGTGGGTGGGACGGGTTGG | |
| Apta_19 | DNA | TGAGGGGGGGGGAGGTCGGGCCTGC | |
| Apta_20 | DNA | AGAGGGGGGGGTGGGGGTGGCCTGC | |
| Apta_26 | DNA | AGGGGGGGGGGTAAGGGTGGGTAGA | |
| Apta_30 | DNA | AGAGGGGGGGGTGGAGGGGGCTAGA | |
| Apta_63 | DNA | GACCCGTGGTAGGGTAGGATGGGGTGGTC | |
| Apta_66 | DNA | TACCGTGGTAGGGAAGGTTGGAGTGTA | |
| Apta_389 | DNA | GCCTGTGGTGTTGGGGCGGGTGCG | |
| Apta_757 | DNA | GGTGGTGGTGGTTGTGGTGGTGG |
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