AptaDB: Result

Interaction ID: 1070

Aptamer sequence: CGTGTATCCCCTGTGTGTTTGTACTCGGCTACTGTATCCG

Target unique ID: 43504

Aptamer ID	Aptamer descriptor	Target chemistry	Target name	Affinity	Binding Conditions/Buffer	PubMed ID
Apta_986	Hp4	Cell	Helicobacter pylori	26.38 nM	100 mM NaCl, 5 mM KCl, 50 mM Tris-HCl, and 1 mM MgCl2, pH 7.5	33585756

Aptamer Sequence:	CGTGTATCCCCTGTGTGTTTGTACTCGGCTACTGTATCCG
The optimal secondary structure in dot-bracket notation:	...(((.((...(((......)))..)).)))........
The centroid secondary structure in dot-bracket notation:	........................................

The MFE structure

The Centroid structure

The mountain plot representation

Type	Detail	Type	Detail
Aptamer ID	Apta_986	Description	Hp4
Aptamer chemistry	DNA	Length	40 nt
GC content	52.5%	Molecular weight	12,226.82 Da
Molarity of 1 μg/μl solution	81.79 μM	Number of G-quadruplexes	No QGRS found
G-Score	N/A	Function	Aptasensor
Sequence	CGTGTATCCCCTGTGTGTTTGTACTCGGCTACTGTATCCG
Applications	Detect H. pylori with the naked eye for 5 min using illumination from a hand-held flashlight

Type	Detail	Type	Detail
ATCC ID	43504	Cell name	Helicobacter pylori
Category	N/A	Organism	N/A
Product type	N/A	Cell type	N/A
Morphology	N/A	Tissue	N/A
Disease	N/A	Product format	Frozen
Antigen expression	N/A	Genes expressed	N/A
Cell description	Whole-genome sequenced bacterial type strain isolated from the human gastric antrum. This strain can be used in enteric research or as a quality control strain.
Application(s)	Bioinformatics; Enteric disease research; Infectious disease research; Media testing; Quality control

No relevant experimental diagram	Interaction ID	1070
	Target type	Cell
	Target unique ID	43504
	Activity	26.38 nM
	Binding Conditions/Buffer	100 mM NaCl, 5 mM KCl, 50 mM Tris-HCl, and 1 mM MgCl2, pH 7.5
	Assay	N/A
	PubMed ID	33585756

Aptamer ID	Aptamer chemistry	Sequence	Similarity
Apta_387	DNA	CTTTAATGCCCTTCACTAGGTCTAAGCTACTACTTACCCG	57.50%
Apta_480	DNA	CGGCACACCTCGGTCGGTTTGTATGGCGAGCTGGTTTTTT	57.50%
Apta_604	DNA	TCCTGACCTTAGCCTATGTTTTCTCTACCGGCTATGTTAC	57.50%
Apta_143	DNA	GGTGCGGTTCGTGCGGTTGTAGTACTCGTGGCCGATAGAGGTAGTTTCG	55.10%
Apta_146	DNA	GGTGCGGTTCGTGCGGTTGTAGTACTCGTGGCCG	55.00%
Apta_479	DNA	CGGCCCACCTCGGTCGGTTTGTATGGCGAGCTGGTTTTTT	55.00%
Apta_481	DNA	CGGCCCACCTCGGTCGGTTTGTATGGCGAGCTGGTTTTTA	55.00%
Apta_858	DNA	GGCTTCAGGTTGGTCTGGTTGGGTTTGGCTCCTGTGTACG	55.00%
Apta_1247	DNA	GGTGGTTGCTGTTGTTTGTGGTTGGTGTGC	55.00%
Apta_861	DNA	CAGGTTGGTCTGGTTGGGTTTGGCTCCTGTGTACGCAACCTG	54.76%
Apta_1278	DNA	CCATGATTCAACTTTACTGGTCTTGTCTTGGCTAGTCGTGTGTCATTCCCTAAGG	54.55%
Apta_1071	DNA	TTGAAGTGACTCCGCACTGGGTGGGTGGGAGGGTCGTGCGGCTGGTCATAGCAGGGT	52.63%
Apta_363	DNA	ATTGACCGCTGTGTGACGCAACACTCAAT	52.50%
Apta_364	DNA	TATGGTATGCTGTGTGGTATGGGGTGGCGTGCTCT	52.50%
Apta_543	DNA	GGCACGTGTTGTCTCTCTGTGTCTCGTGCC	52.50%
Apta_681	DNA	CCTGACGATCGGGTGTGGGTTGGCTTGAGG	52.50%
Apta_1059	DNA	TCGTGACGCCGTGCAGTTACCGATACGAGCCTCGTTTTG	52.50%
Apta_1094	DNA	GGAATCGTGGGTGGTAGGGTAGGGGATGCA	52.50%
Apta_1176	DNA	AGTATGATATCGGTGTTTATGGTGTCTGTCTTCATACT	52.50%
Apta_1210	DNA	GGGGAGGCAGTGTGTTGTGTCGTGTGTGTGCTTGG	52.50%

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