Aptamer-target interaction descriptor
Aptamer-target interaction information
Interaction ID: 1008
Aptamer sequence: ACTTCGGCTAGTTAGGGGGTAGTTTAGATCGTCTCTACAT
Target unique ID: Other-31
| Aptamer ID | Aptamer descriptor | Target chemistry | Target name | Affinity | Binding Conditions/Buffer | PubMed ID |
|---|---|---|---|---|---|---|
| Apta_915 | C10 | Other | Rituximab | 17.6 nM | 20 mM Tris pH 7.6, 100 mM NaCl, 2 mM MgCl2, 5 mM KCl, 1 mM CaCl2, 0.02% v/v Tween 20 | 33151990 |
Structure information of aptamer
| Aptamer Sequence: | ACTTCGGCTAGTTAGGGGGTAGTTTAGATCGTCTCTACAT |
| The optimal secondary structure in dot-bracket notation: | .((((.........))))((((............)))).. |
| The centroid secondary structure in dot-bracket notation: | ........................................ |
The MFE structure
The Centroid structure
The mountain plot representation
Aptamer information
| Type | Detail | Type | Detail |
|---|---|---|---|
| Aptamer ID | Apta_915 | Description | C10 |
| Aptamer chemistry | DNA | Length | 40 nt |
| GC content | 45.0% | Molecular weight | 12,347.93 Da |
| Molarity of 1 μg/μl solution | 80.99 μM | Number of G-quadruplexes | No QGRS found |
| G-Score | N/A | Function | Target detection |
| Sequence | ACTTCGGCTAGTTAGGGGGTAGTTTAGATCGTCTCTACAT | ||
| Applications | Detection of rituximab | ||
Target information
| Type | Detail | Type | Detail |
|---|---|---|---|
| Target ID | Other-31 | Name | Rituximab |
Activity data
 |
Interaction ID | 1008 |
| Target type | Other | |
| Target unique ID | Other-31 | |
| Activity | 17.6 nM | |
| Binding Conditions/Buffer | 20 mM Tris pH 7.6, 100 mM NaCl, 2 mM MgCl2, 5 mM KCl, 1 mM CaCl2, 0.02% v/v Tween 20 |
|
| Assay | Titration of aptamers for heat-treated rituximab binding using ELASA |
|
| PubMed ID | 33151990 |
Similar aptamers
| Aptamer ID | Aptamer chemistry | Sequence | Similarity |
|---|---|---|---|
| Apta_185 | DNA | ACCAAGGCTTTAGGTCTGAGATCTCCCAAT | |
| Apta_195 | DNA | AGGAAGGCTTTAGGGGTCTGAGATCTCGGAAT | |
| Apta_391 | DNA | ACCGTGGAGGATAGTTCGGTGGCTGTTCAGGGTCTCCTCCACGGT | |
| Apta_393 | DNA | AGGAGGATAGTTCGGTGGCTGTTCAGGGTCTCCTCCT | |
| Apta_193 | DNA | AGGAAGGCTTTAGGGTCTGAGATCTCGGAAT | |
| Apta_194 | DNA | AGGAAGGCTTTAGGGTCTGAGATCTCGGGAAT | |
| Apta_392 | DNA | GGATAGTTCGGTGGCTGTTCAGGGTCTCCTCCT | |
| Apta_1081 | DNA | CTTACGACTGTGGTCGGGTGGTGGGCCTCTAGAGGGGTGTCGTAAG | |
| Apta_745 | DNA | GGTTGCATGCCGTGGGGAGGGGGGTGGGTTTTATAGCGTACTCAG | |
| Apta_750 | DNA | ATGCGAACAGGTGGGTGGGTTGGGTGGATTGTTCGGCTTCTTGAT | |
| Apta_845 | DNA | CCAAACGCGCTGGTTTGGAATGCTTAGAGTTTGATCGATGCCTAA | |
| Apta_72 | DNA | AGTCAGTAGGTTGGTGTGGTTGGGGCTGACT | |
| Apta_184 | DNA | AGGAAGGCTTTAGGTCTGAGATCTCGGAAT | |
| Apta_202 | DNA | AAGGCTTTAGGTCTGAGATCTCGGAAT | |
| Apta_682 | DNA | CCTTGTAGATCGGGTGTGGTTTGGCGTAGG | |
| Apta_858 | DNA | GGCTTCAGGTTGGTCTGGTTGGGTTTGGCTCCTGTGTACG | |
| Apta_1065 | DNA | CCTCGCTATGATGGAGTGCGTTTAGATCAGGGAACGGGTT | |
| Apta_882 | DNA | AATAGTCTGGTTCGGTGCTTGGTGCGATGTGTTAGTCAGACTCTTGTGTG | |
| Apta_749 | DNA | GATCGGTGGGTGGGGGGGTTGGAGATCATCCTCAGGGATTACGTC | |
| Apta_1117 | DNA | CGTACGGAATTCGCTAGCGGACTGGAGTCTAGACCGGGTAGCTGTGGTGGATCCGAGCTCCACGTG |
DEV TOOL
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