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Paper-scoped peptide mentionSequence reported

Me6I2-BODIPY-OT

PMC13206411::PEP000013

Source publication

Photocaged Oxytocin and Vasopressin Probes to Decipher Neuropeptide Signalling With High Spatiotemporal Resolution.

Angewandte Chemie (International Ed. in English) · 2026

DOI 10.1002/anie.202513373 PMC13206411 PMID 41972501

Sequence status: reported
Standardization: Sequence ready
Source location: unknown
Activity records: 6

Sequence evidence

Reported molecular identity

CYIQNCPLG

CYIQNCPLG

Resolved peptide links

PEPDIA-PLP-003437 CTPDB_P005427

Experimental observations

Records linked to this mention

OtherAnti-HIVPositive observation

Figure 5A; Table S2. Me6I2-BODIPY-OT 5 on hOTR. Text: '3- to 9-fold rightward shift in EC50 compared to OT'.

Mention PMC13206411::PEP000013PMC13206411text

Measure: EC50
Value: =5
Target: Homo sapiens
Assay: Not reported by source

Source publication

OtherAnti-HIVPositive observation

Figure 5D; Table S3. Me6I2-BODIPY-OT 5* on hOTR. Text: 'only a minor increase in activity (~2-fold)'.

Mention PMC13206411::PEP000013PMC13206411text

Measure: EC50
Value: ~2
Target: Homo sapiens
Assay: Not reported by source

Source publication

OtherAntibacterialNegative / threshold

Figure 5F. Me6I2-BODIPY-OT 5 at 100 nM on hV1aR. Text: 'most caged photoprobes exhibited no activity at 100 nM'.

Mention PMC13206411::PEP000013PMC13206411text

Measure: percent_inhibition
Value: na
Target: Homo sapiens
Assay: Not reported by source

Source publication

OtherAntibacterialNegative / threshold

Figure 5F. Me6I2-BODIPY-OT 5 at 100 nM on hV1bR. Text: 'most caged photoprobes exhibited no activity at 100 nM'.

Mention PMC13206411::PEP000013PMC13206411text

Measure: percent_inhibition
Value: na
Target: Homo sapiens
Assay: Not reported by source

Source publication

ToxicityCytotoxicPositive observation

Figure 4. Me6I2-BODIPY-OT 5 in MTT assay. Text: 'except for 1 uM 5' exhibited higher cell viability than unmodified OT.

Mention PMC13206411::PEP000013PMC13206411text

Measure: cell_viability
Value: =4%
Target: Homo sapiens
Assay: Not reported by source

Source publication

ToxicityCytotoxicPositive observation

Figure 4. Me6I2-BODIPY-OT 5* in MTT assay. Text: 'The uncaged compound mixtures exhibited values comparable to those of OT'.

Mention PMC13206411::PEP000013PMC13206411text

Measure: cell_viability
Value: =4%
Target: Homo sapiens
Assay: Not reported by source

Source publication

Local peptide labels such as P1, PEP1, or peptide 1 are grouped only within this paper and are not assumed to represent the same molecule across publications.