ProForma 2.0
not generated modification context
Not calculated for this record
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PEPDIA-INT-005427
GoldPepDiana tier derived from the internal quality score plus activity and literature coverage; it is not an external database rating.Oxytocin
70
Quality PepDiana 0–100 composite of sequence, source, activity, literature, and cross-database evidence completeness.
3
Source DBs
4
Activities
7
Source refs
1
Literature
0
Patents
Integrated record
Sequence and molecular profile
CYIQNCPLG
Indexed sequence9 aa
1CYIQNCPLG
Length
9
Molecular weight
-
Formula
-
Structure type
Cyclic
Synthesis
-
Chirality
-
Family
-
Gene
-
Residue composition
C
2
Y
1
I
1
Q
1
N
1
P
1
L
1
G
1
Physicochemical profile
Hydrophobic3
Membrane affinity proxy
Polar4
Solubility proxy
Charged0
Net charge proxy +0
Aromatic1
Binding interaction proxy
Versioned scientific descriptors
Physicochemical properties and standard representations
Reported properties
Legacy compatibility fields are materialized from the versioned PepDiana computed release; no separate source-reported property is available.
Computed properties
physchem-20260620Molecular weight
1010.1878 Da
Molecular formula
Not calculated
Theoretical pI
5.5107
Net charge at pH 7
-0.2607
GRAVY
0.3333
Instability index
27.0889
Aromaticity
0.1111
Topological polar surface area
Not calculated
cLogP
Not calculated
Hydrogen-bond donors
Not calculated
Hydrogen-bond acceptors
Not calculated
Rotatable bonds
Not calculated
Method: PepDiana sequence/structure descriptor pipeline
Tool: Biopython+RDKit · Biopython 1.85; RDKit 2024.09.6
Calculated: 2026-06-20T11:01:38.358971+00:00
Assumptions: ph=7; termini=free N-terminus and free C-terminus for simple linear peptides; stereochemistry=standard L-amino acids; smiles_length_limit=200
Sequence representations
HELM 2.0
not generated modification context
Not calculated for this record
Canonical SMILES
not generated modification context
Not calculated for this record
Isomeric SMILES
not generated modification context
Not calculated for this record
Follow-up research
External analysis tools
Run BLASTPSearch similar protein or peptide sequences at NCBI.Search UniProtLook for related UniProtKB entries using the sequence.Search PubMedFind literature context for this peptide record.
Links open third-party resources with the current PepDiana sequence, record name, or chemistry notation as the initial query.
Research workflow
Citation and local history
BibTeX
@misc{PEPDIA-INT-005427,
title = {Oxytocin},
author = {{PepDiana Consortium}},
year = {2026},
howpublished = {PepDiana Multifunctional Peptide Database},
url = {http://127.0.0.1:3004/peptides/PEPDIA-INT-005427},
note = {Accessed from local PepDiana development build}
}APA-style note
Oxytocin. (2026). PepDiana record PEPDIA-INT-005427. PepDiana Multifunctional Peptide Database. http://127.0.0.1:3004/peptides/PEPDIA-INT-005427
This record is saved to local recent-view history so it can reappear on the peptide browser page.
Integrated source-database annotations
Biological activity (4 records)
| Stable record | Activity | Subtype | Value | Target | Assay method | Source |
|---|---|---|---|---|---|---|
| CTPDB_P005427_ACT_satpdb_0000 | Cell-Penetrating | Drug Delivery | Not available in the current structured import | Unknown | Not reported by source | satpdb12919satpdb / linked |
| CTPDB_P005427_ACT_satpdb_0001 | Bioregulatory | Cell-Cell Communication | Not available in the current structured import | Unknown | Not reported by source | satpdb23956satpdb / linked |
| CTPDB_P005427_ACT_thpdb_0002 | Clinical / Approved Drug | General Therapeutic | Not available in the current structured import | Unknown | Not reported by source | Th1087_10476_rec0thpdb / unavailable |
| CTPDB_P005427_ACT_thpdb_0003 | Clinical / Approved Drug | General Therapeutic | Not available in the current structured import | Unknown | Not reported by source | Th1087_10477_rec1thpdb / unavailable |
Sequence-linked cross-layer evidence
Linked primary-literature evidence
20
Records
1
Papers
12
Positive
8
Negative
1
Primary identities
These observations were collected directly from primary literature and linked by identical normalized sequence. They remain a separate evidence layer and do not overwrite Integrated source-database annotations.
Provenance
Source database records (7)
Citation trail
Literature (1 records)
-
-
Audit surface
Raw annotations and release metadata
Integrated record last updated: 2026-04-15T00:59:13.664756+00:00
Modification summary
No structured modification annotations are available for this record.
ADMET
{
"toxicity": [
{
"source_db": "thpdb",
"assay_method": "Administration of supratherapeutic doses of exogenous oxytocin can lead to myocardial ischemia, tachycardia, and arrhythmias. High doses can also lead to uterine spasms, hypertonicity, or rupture. Oxy",
"toxicity_type": "Toxicity"
},
{
"source_db": "thpdb",
"assay_method": "Administration of supratherapeutic doses of exogenous oxytocin can lead to myocardial ischemia, tachycardia, and arrhythmias. High doses can also lead to uterine spasms, hypertonicity, or rupture. Oxy",
"toxicity_type": "Toxicity"
}
]
}Source metadata
[
{
"source_db": "b3pdb",
"organism_name": "Unknown"
},
{
"source_db": "satpdb",
"organism_name": "Unknown"
},
{
"source_db": "thpdb",
"organism_name": "Unknown"
}
]Structure metadata
{
"source_db": "satpdb",
"dssp_states": "CCGGGCSCC"
}