OtherAnti-HIVNegative / threshold
Record detail Figure 5A; Table S2. DCMAC-OT 1 on hOTR. Text: '150 → >3900-fold higher EC50 values than parent peptides'.
- Measure
- EC50
- Value
- >3,900
- Target
- Homo sapiens
- Assay
- Not reported by source
Source publication
Photocaged Oxytocin and Vasopressin Probes to Decipher Neuropeptide Signalling With High Spatiotemporal Resolution.
Angewandte Chemie (International Ed. in English) · 2026
- Sequence status
- reported
- Standardization
- Sequence ready
- Source location
- unknown
- Activity records
- 6
Sequence evidence
Reported molecular identity
CYIQNCPLG
CYIQNCPLG
Resolved peptide links
Experimental observations
Records linked to this mention
OtherAnti-HIVPositive observation
Record detail Figure 5D; Table S3. DCMAC-OT 1* on hOTR. Text: '75-fold increase in potency for hOTR'.
- Measure
- EC50
- Value
- =1
- Target
- Homo sapiens
- Assay
- Not reported by source
OtherAntibacterialNegative / threshold
Record detail Figure 5F. DCMAC-OT 1 at 100 nM on hV1aR. Text: 'most caged photoprobes exhibited no activity at 100 nM'.
- Measure
- percent_inhibition
- Value
- na
- Target
- Homo sapiens
- Assay
- Not reported by source
OtherAntibacterialNegative / threshold
Record detail Figure 5F. DCMAC-OT 1 at 100 nM on hV1bR. Text: 'most caged photoprobes exhibited no activity at 100 nM'.
- Measure
- percent_inhibition
- Value
- na
- Target
- Homo sapiens
- Assay
- Not reported by source
ToxicityCytotoxicPositive observation
Record detail Figure 4. DCMAC-OT 1 in MTT assay. Text: 'Most photocaged OT probes ... exhibited higher cell viability than unmodified OT'.
- Measure
- cell_viability
- Value
- =4%
- Target
- Homo sapiens
- Assay
- Not reported by source
ToxicityCytotoxicPositive observation
Record detail Figure 4. DCMAC-OT 1* in MTT assay. Text: 'The uncaged compound mixtures exhibited values comparable to those of OT'.
- Measure
- cell_viability
- Value
- =4%
- Target
- Homo sapiens
- Assay
- Not reported by source
Local peptide labels such as P1, PEP1, or peptide 1 are grouped only within this paper and are not assumed to represent the same molecule across publications.