MetaADEDB 2.0 @ LMMD
Megestrol
(VXIMPSPISRVBPZ-NWUMPJBXSA-N)
Structure
SMILES
O=C1CC[C@]2(C(=C1)C(=C[C@@H]1[C@@H]2CC[C@]2([C@H]1CC[C@]2(O)C(=O)C)C)C)C
Molecular Formula:
C22H30O3
Molecular Weight:
342.472
Log P:
4.0045
Hydrogen Bond Acceptor:
3
Hydrogen Bond Donor:
1
TPSA:
54.37
CAS Number(s):
3562-63-8
Synonym(s)
1.
Megestrol
External Link(s)
MeSHD008535
PubChem Compound19090
CHEMBLCHEMBL4071215
IUPHAR/BPS Guide to PHARMACOLOGY9128
KEGGcpd:C07120
dr:D08167
Therapeutic Target DatabaseD04GJN
ZINC4097356
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Pulmonary EmbolismFAERS: 7
Canada Vigilance: 1		Canada Vigilance
SIDER
US FAERS
2Deep Vein ThrombosisFAERS: 4SIDER
US FAERS
3MeningiomaFAERS: 4US FAERS
4ThrombosisFAERS: 2US FAERS
5Abdominal PainFAERS: 1OFFSIDES
SIDER
US FAERS
6BlindnessFAERS: 1US FAERS
7Blood glucose increasedFAERS: 1US FAERS
8Drug prescribing errorFAERS: 1US FAERS
9DysarthriaFAERS: 1US FAERS
10EcchymosisFAERS: 1US FAERS
11HypotensionFAERS: 1SIDER
US FAERS
12NeutropeniaFAERS: 1US FAERS
13Peripheral artery occlusionFAERS: 1US FAERS
14PneumoniaFAERS: 1SIDER
US FAERS
15Premenstrual syndromeFAERS: 1US FAERS
16Steroid withdrawal syndromeFAERS: 1US FAERS
17ThrombocytopeniaFAERS: 1US FAERS
18Weight decreasedFAERS: 1US FAERS
19AbasiaOFFSIDES
20Abnormal visionOFFSIDES
21AbscessOFFSIDES
22Acid refluxOFFSIDES
23AcneOFFSIDES
24Activities of daily living impairedOFFSIDES
25Adenocarcinoma65687CTD
OFFSIDES
26AlbuminuriaSIDER
27AlopeciaSIDER
28AmblyopiaSIDER
29AmphetaminesOFFSIDES
30Anal FistulaOFFSIDES
31AnhedoniaOFFSIDES
32AnorexiaOFFSIDES
33AnxietyOFFSIDES
34Arterial Occlusive Diseases788979CTD
35ArteriosclerosisOFFSIDES
36ArthropathyOFFSIDES
37AscitesOFFSIDES
38AstheniaOFFSIDES
SIDER
39AsthmaOFFSIDES
40AtelectasisOFFSIDES
41Atrial tachycardiaOFFSIDES
42AuraOFFSIDES
43BK virus infectionOFFSIDES
44Bacterial EndocarditisOFFSIDES
45Bacterial sepsisOFFSIDES
46Biopsy bladder abnormalOFFSIDES
47Blood GlucoseOFFSIDES
48Blood albumin decreasedOFFSIDES
49Blood amylase increasedOFFSIDES
50Blood creatinine increasedOFFSIDES
51Blood glucose abnormalOFFSIDES
52Blood glucose decreasedOFFSIDES
53Blood lactate dehydrogenase increasedSIDER
54Blood osmolarity decreasedOFFSIDES
55Blood potassium decreasedOFFSIDES
56Blood potassium increasedOFFSIDES
57Blood sodiumOFFSIDES
58Blood uric acid decreasedOFFSIDES
59Bone density decreasedOFFSIDES
60Bone erosionOFFSIDES
61Bone lesionOFFSIDES
62Bone painOFFSIDES
63Bone scan abnormalOFFSIDES
64Bone swellingOFFSIDES
65BronchitisOFFSIDES
66BursitisOFFSIDES
67Candida sepsisOFFSIDES
68Carcinoembryonic antigen increasedOFFSIDES
69Carpal Tunnel SyndromeSIDER
70Cataract operationOFFSIDES
71CataractOFFSIDES
72Catheter related complicationOFFSIDES
73Catheter related infectionOFFSIDES
74Catheter sepsisOFFSIDES
75Catheter site infectionOFFSIDES
76CellulitisOFFSIDES
77Cerebral atrophyOFFSIDES
78Chest PainSIDER
79Choking sensationOFFSIDES
80Chronic Obstructive Airway DiseaseOFFSIDES
81Clostridium difficile colitisOFFSIDES
82ConfabulationOFFSIDES
83Congenital tricuspid valve incompetenceOFFSIDES
84ConstipationSIDER
85Contact DermatitisOFFSIDES
86DeafnessOFFSIDES
87DebridementOFFSIDES
88DehydrationOFFSIDES
89DemyelinationOFFSIDES
90DermatitisSIDER
91Device related infectionOFFSIDES
92Diabetes MellitusSIDER
93DiarrheaOFFSIDES
94Diastolic dysfunctionOFFSIDES
95DiplopiaOFFSIDES
96DiscomfortSIDER
97Disease ProgressionOFFSIDES
98Dissociative disorderOFFSIDES
99Disturbance in sexual arousalSIDER
100DizzinessOFFSIDES
SIDER
101DrowsinessOFFSIDES
102DuodenitisOFFSIDES
103DyspepsiaSIDER
104Economic problemOFFSIDES
105Ejection Fraction DecreasedOFFSIDES
106Electromechanical dissociationOFFSIDES
107EmbolismSIDER
108EndocarditisOFFSIDES
109Endodontic procedureOFFSIDES
110Endometrial Neoplasms65687CTD
111Enterococcal infectionOFFSIDES
112EpistaxisOFFSIDES
113Erectile dysfunctionSIDER
114EscharOFFSIDES
115Escherichia sepsisOFFSIDES
116Extremity contractureOFFSIDES
117Facial NeuralgiaOFFSIDES
118Failure to ThriveOFFSIDES
119FatigueOFFSIDES
120Febrile NeutropeniaOFFSIDES
121Feeling abnormalSIDER
122Flank PainOFFSIDES
123FlatulenceSIDER
124Fluid overloadOFFSIDES
125Fluid replacementOFFSIDES
126FolliculitisOFFSIDES
127GangreneOFFSIDES
128GastroenteritisOFFSIDES
129Gastrointestinal PainSIDER
130General physical health deteriorationOFFSIDES
131GlaucomaOFFSIDES
132GlomerulonephritisOFFSIDES
133GoutOFFSIDES
134GranulocytosisOFFSIDES
135HaematotoxicityOFFSIDES
136HeadacheSIDER
137HepatomegalySIDER
138Herpes NOSSIDER
139High frequency ablationOFFSIDES
140HordeolumOFFSIDES
141HydrocephalusOFFSIDES
142HydronephrosisOFFSIDES
143HypercreatininaemiaOFFSIDES
144HypersensitivitySIDER
145Hypertension, Renovascular788979CTD
146Hypoaesthesia facialOFFSIDES
147Hypocoagulable stateOFFSIDES
148HypogonadismOFFSIDES
149HypophagiaOFFSIDES
150HyporeflexiaOFFSIDES
151Impaired gastric emptyingOFFSIDES
152Impaired work abilityOFFSIDES
153IncontinenceOFFSIDES
154InfectionOFFSIDES
SIDER
155Infusion site mobility decreasedOFFSIDES
156Intermittent ClaudicationOFFSIDES
157Intervertebral Disc DegenerationOFFSIDES
158Joint sprainOFFSIDES
159Kidney FailureOFFSIDES
160Lactic dehydrogenase activity increasedSIDER
161LethargyOFFSIDES
SIDER
162LeukopeniaSIDER
163LipaseOFFSIDES
164Lumbar radiculopathyOFFSIDES
165MalaiseCanada Vigilance: 1Canada Vigilance
SIDER
166Malignant neoplasm progressionOFFSIDES
167Markedly reduced dietary intakeOFFSIDES
168Mass excisionOFFSIDES
169Mastication disorderOFFSIDES
170Mental status changesOFFSIDES
171Metastatic NeoplasmOFFSIDES
172MetrorrhagiaSIDER
173Mood swingsSIDER
174Multiple MyelomaOFFSIDES
175Muscle WeaknessOFFSIDES
176Musculoskeletal chest painOFFSIDES
177Musculoskeletal discomfortOFFSIDES
178MyelodysplasiaOFFSIDES
179NauseaOFFSIDES
SIDER
180Nephrogenic Fibrosing DermopathyOFFSIDES
181NeuralgiaOFFSIDES
182NeuropathySIDER
183Neutropenic sepsisOFFSIDES
184Ocular icterusOFFSIDES
185OliguriaOFFSIDES
186Optic AtrophyOFFSIDES
187Optic NeuropathyOFFSIDES
188Oral candidiasisSIDER
189Osteitis DeformansOFFSIDES
190OsteomyelitisOFFSIDES
191OsteopeniaOFFSIDES
192PO2 decreasedOFFSIDES
193PainOFFSIDES
SIDER
194PalpitationsCanada Vigilance: 1Canada Vigilance
SIDER
195PancreatitisOFFSIDES
196Peptostreptococcus infectionOFFSIDES
197Perianal abscessOFFSIDES
198Pericardial effusionOFFSIDES
199PericarditisOFFSIDES
200PeriodontitisOFFSIDES
201PharyngitisSIDER
202Physical disabilityOFFSIDES
203PneumothoraxOFFSIDES
204Polymyalgia RheumaticaOFFSIDES
205Portal hypertensive gastropathyOFFSIDES
206Post procedural discomfortOFFSIDES
207PregnancySIDER
208Productive CoughOFFSIDES
209Protein total decreasedOFFSIDES
210PruritusSIDER
211Recall phenomenonOFFSIDES
212Renal cystOFFSIDES
213Renal tubular necrosisOFFSIDES
214Respiratory FailureOFFSIDES
215Retinal Vein OcclusionOFFSIDES
216Retinoic acid syndromeOFFSIDES
217Risus sardonicusOFFSIDES
218Septic ShockOFFSIDES
219SequestrectomyOFFSIDES
220Sinus headacheOFFSIDES
221SinusitisOFFSIDES
222Skin IndurationOFFSIDES
223Skin hypertrophyOFFSIDES
224Skin lesionOFFSIDES
225Spinal column stenosisOFFSIDES
226Splenic neoplasm malignancy unspecifiedOFFSIDES
227SpondylitisOFFSIDES
228StarvationOFFSIDES
229StressSIDER
230Supraventricular tachycardiaOFFSIDES
231SweatingSIDER
232Synovial CystOFFSIDES
233ThromboembolismSIDER
234ThrombophlebitisOFFSIDES
SIDER
235Thrombosis in deviceOFFSIDES
236Tooth ExtractionOFFSIDES
237Unresponsive to stimuliOFFSIDES
238Urethral StenosisOFFSIDES
239Urinary IncontinenceSIDER
240Urinary tract infectionSIDER
241UrticariaSIDER
242Ventricular FibrillationOFFSIDES
243Ventricular hypokinesiaOFFSIDES
244Vesiculobullous rashSIDER
245Vitamin B 12 DeficiencyOFFSIDES
246Vitreous DetachmentOFFSIDES
247VomitingSIDER
248Walking aid userOFFSIDES
249White blood cell count abnormalOFFSIDES
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