Aptamer-target interaction descriptor
Aptamer-target interaction information
Interaction ID: 945
Aptamer sequence: GGGAGUCUGAAGUCGGACUUGUUAUCAAUUCACUUCAGACU
Target unique ID: Other-7
| Aptamer ID | Aptamer descriptor | Target chemistry | Target name | Affinity | Binding Conditions/Buffer | PubMed ID |
|---|---|---|---|---|---|---|
| Apta_859 | 9-41U22 | Other | Ribosome-inactivating Protein, Pepocin | 18 nM | 3 mM NaH2PO4, 3 mM MgCl2, 45 mM NaCl, 2.5 mM EDTA, 3 mM Tris-HCl (pH 7.5), 0.15 mM DTT, and 12% glycerol | 10671532 |
Structure information of aptamer
| Aptamer Sequence: | GGGAGUCUGAAGUCGGACUUGUUAUCAAUUCACUUCAGACU |
| The optimal secondary structure in dot-bracket notation: | ...((((((((((.(((.(((....)))))))))))))))) |
| The centroid secondary structure in dot-bracket notation: | ...((((((((((.(((.(((....)))))))))))))))) |
The MFE structure
The Centroid structure
The mountain plot representation
Aptamer information
| Type | Detail | Type | Detail |
|---|---|---|---|
| Aptamer ID | Apta_859 | Description | 9-41U22 |
| Aptamer chemistry | RNA | Length | 41 nt |
| GC content | 43.9% | Molecular weight | 13,103.76 Da |
| Molarity of 1 μg/μl solution | 76.31 μM | Number of G-quadruplexes | No QGRS found |
| G-Score | N/A | Function | Targeted binding |
| Sequence | GGGAGUCUGAAGUCGGACUUGUUAUCAAUUCACUUCAGACU | ||
| Applications | Inhibit the ribosome-inactivating protein | ||
Target information
| Type | Detail | Type | Detail |
|---|---|---|---|
| Target ID | Other-7 | Name | Ribosome-inactivating Protein, Pepocin |
Activity data
 |
Interaction ID | 945 |
| Target type | Other | |
| Target unique ID | Other-7 | |
| Activity | 18 nM | |
| Binding Conditions/Buffer | 3 mM NaH2PO4, 3 mM MgCl2, 45 mM NaCl, 2.5 mM EDTA, 3 mM Tris-HCl (pH 7.5), 0.15 mM DTT, and 12% glycerol |
|
| Assay | Binding curves for anti-pepocin aptamers with pepocin or gypsophilin |
|
| PubMed ID | 10671532 |
Similar aptamers
| Aptamer ID | Aptamer chemistry | Sequence | Similarity |
|---|---|---|---|
| Apta_92 | RNA | ACAACUUAAUGCGACGUUGGUAAAGCAUAUCAAAC | |
| Apta_633 | RNA | GGCAUCGGAAAGUGGGUUGAUGUAAGUAACAGGCGAUGCC | |
| Apta_1167 | RNA | GGCGCGAGGAAGGAGGUCUGAGGAGGUCACUGCGCC | |
| Apta_315 | RNA | GGGAGGACGAUGCGGUCGUAUUAUCCGCUGCACGCCAGACGACUCGCCCGA | |
| Apta_129 | RNA | GGGAGGACGAUGCGGACACCGUUAAUCUGAGGCCCUGUCCUAUUCCUUCACGCCUCAGA | |
| Apta_136 | RNA | CGUGUCGUCCUGGUACGAUUUGGUAUAUAACCGUGGCUUUUCGACA | |
| Apta_230 | RNA | GGGAGGACGAUGCGGGCGUGAAUGGUGUUGUGAGG | |
| Apta_634 | RNA | GGUCUUACGUCGUUCGCGACUAUUGGGAGACC | |
| Apta_1121 | RNA | GACAGCGUGCCUAGAAGUCCAAGCUUAAAUAACCACGCUCGACAAGC | |
| Apta_131 | RNA | GGGAGGACGAUGCGGUCCUGUCGUCUGUUCGUCCCCAGACGACUCGCCCGA | |
| Apta_271 | RNA | CUGUCGAGCAUGCUCAGGGUAACGUAUAGUCAAGACACCUCAAGUGUAACU | |
| Apta_270 | RNA | CUGUCGAACAUGCUGAGGGUAACGUACUGGCAAGCUCACCUCAGCGUAGCUAa | |
| Apta_520 | RNA | GGGAGAUCUACGGAUCUCAGGGCUCUUACGGGAGCUACAUGGAAGGAGUCCAUGUGU | |
| Apta_269 | RNA | AACGCUCAACGUCAGAAGGCAACGUAUAGGCAAGCACACUUCGACAUGAGGC | |
| Apta_431 | RNA | CAGGCAUGCCUAGCUAAGCAGCCCAUGGCUUAUGCGCGGAAUAUUGGCUUCCGUUC | |
| Apta_1249 | RNA | AAUCGGCCCAAUUUUACCUUCGGACUUCAGUAUCUAGUGUGGCUUUAAAUCAUAGC | |
| Apta_135 | RNA | GGGAGGACGAUGCGGAUUCUGGUUACUGGCCGCCCCAGACGACUCGCCCGA | |
| Apta_1143 | RNA | ACGAGUUGUCGCAUGUGCGGUUCAGUCUGGUCCUUCAGCACCGUACAACAA | |
| Apta_1 | RNA | ACGAAGCUUGAUCCCGUUUGCCGGUCGAUCGCUUCGA | |
| Apta_51 | RNA | GCCUUAGUAACGUGCUUUGAUGUCGAUUCGACAGGAGGC |
DEV TOOL
 |
 |
 |
 |