AptaDB: Result

Interaction ID: 938

Aptamer sequence: CATCTGTGTGAAGACTATATGGCGCTCACATATTTCTTTC

Target unique ID: Other-2

Aptamer ID	Aptamer descriptor	Target chemistry	Target name	Affinity	Binding Conditions/Buffer	PubMed ID
Apta_852	SMV-25	Other	Human Norovirus	232 nM	500 ml of binding buffer [consisting of phosphate buffered saline (pH 7.1) supplemented with 100 mg/L CaCl2, 100 mg/L MgCl2 and 0.05% Tween 20] at Room Temperature	25192421

Aptamer Sequence:	CATCTGTGTGAAGACTATATGGCGCTCACATATTTCTTTC
The optimal secondary structure in dot-bracket notation:	.........(((((..(((((.......))))).))))).
The centroid secondary structure in dot-bracket notation:	.....(((((................))))).........

The MFE structure

The Centroid structure

The mountain plot representation

Type	Detail	Type	Detail
Aptamer ID	Apta_852	Description	SMV-25
Aptamer chemistry	DNA	Length	40 nt
GC content	40.0%	Molecular weight	12,226.87 Da
Molarity of 1 μg/μl solution	81.79 μM	Number of G-quadruplexes	No QGRS found
G-Score	N/A	Function	Target detection
Sequence	CATCTGTGTGAAGACTATATGGCGCTCACATATTTCTTTC
Applications	HuNoV capture and detection assays

Type	Detail	Type	Detail
Target ID	Other-2	Name	Human Norovirus

	Interaction ID	938
	Target type	Other
	Target unique ID	Other-2
	Activity	232 nM
	Binding Conditions/Buffer	500 ml of binding buffer [consisting of phosphate buffered saline (pH 7.1) supplemented with 100 mg/L CaCl2, 100 mg/L MgCl2 and 0.05% Tween 20] at Room Temperature
	Assay	Equilibrium dissociation curves for select aptamers
	PubMed ID	25192421

Aptamer ID	Aptamer chemistry	Sequence	Similarity
Apta_789	DNA	TAACTTTGAAGGAAAGGCTACAAACTCTTC	60.00%
Apta_974	DNA	CATGGTGTCAATACTATACCTTTTGCCGATGGTAACAGTTGGTGGTATCC	54.00%
Apta_991	DNA	AGCAGTGAAGAGGCGAGAGATTTATGAGGGTAGCGTCCACATATGCCAGGATCGTGTTG	52.54%
Apta_158	DNA	CACAGGCTACGGCACGTAGAGCATCACCATGATCCTGTG	52.50%
Apta_240	DNA	TTTTTAATTAAAGCTCGCCATCAAATAGCTTT	52.50%
Apta_306	DNA	CAAGGTAACCAGTACAAGGTGCTAAACGTAATGGCTTCG	52.50%
Apta_360	DNA	GGGAACGCATACGCCGCAGTATTTCCC	52.50%
Apta_850	DNA	CACCAGTGTGTTGAGGTTTGAGCACACTGATAGAGTGTCA	52.50%
Apta_1063	DNA	AACTTATCGGAGCGTGATTTCCGTCTCGCCGCTTTCCTTT	52.50%
Apta_1149	DNA	ATCATGGTGGGTATCGGCACTCGTTGGTTGAT	52.50%
Apta_1198	DNA	CTTTTAAGAACCGGACGAACTAGAATATTATATTTT	52.50%
Apta_573	DNA	CGTACAGTGGGCTATATTGCTGACGTAAGAGCTGCTTTCAATGCATTGGCATAGATGTCA	51.67%
Apta_821	DNA	CACAGTCACTCAGACGGCCGCTATTGTTGCCAGATTGCCTTTGGC	51.11%
Apta_835	DNA	TATGGCGTGGCAAGCTTGGCCCGCTTCTCAAGCATGGTTATCTAC	51.11%
Apta_309	DNA	TAGCCAAGGTAACCAGTACAAGGTGCTAAACGTAATGGCTTCGGCTTAC	51.02%
Apta_510	DNA	TGTAATTTGTCTGCAGCGGTTCTTGATCGCTGACACCATATTATGAAGA	51.02%
Apta_309	DNA	TAGCCAAGGTAACCAGTACAAGGTGCTAAACGTAATGGCTTCGGCTTAC	51.02%
Apta_918	DNA	TTTACTTATTCAATTCCCGTGGGAAGGCTATAGAGGGGCCAGTCTATGAATAAGTTT	50.88%
Apta_570	DNA	GGCAAGATGTGCCCAGAACAGTTGCTTGTATGGTGGGGAGCGTCCATATTGGCTTAAAC	50.85%
Apta_161	DNA	GTGTGCAGATCTGATTGCCTGCGTCAACCTACATACAAC	50.00%

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