Aptamer-target interaction descriptor
Aptamer-target interaction information
Interaction ID: 240
Aptamer sequence: AGCAGCACAGAGGTCAGATGTGGTTCGATGCTGCAAGGTGTTGTCATTTGGCATATGTTACCTATGCGTGCTACCGTGAA
Target unique ID: Other-52
Aptamer ID Aptamer descriptor Target chemistry Target name Affinity Binding Conditions/Buffer PubMed ID
Apta_235 4.4.20 Other Ig E 25 nM PBS and 1 mM MgCl2 (pH 8.0) 15362896
Structure information of aptamer
Aptamer Sequence: AGCAGCACAGAGGTCAGATGTGGTTCGATGCTGCAAGGTGTTGTCATTTGGCATATGTTACCTATGCGTGCTACCGTGAA
The optimal secondary structure in dot-bracket notation: .((((((..(((..((....)).)))..)))))).........((((.((((((.(((.....))).))))))..)))).
The centroid secondary structure in dot-bracket notation: .((((((..((...((....))..))..))))))..............................................
The MFE structure
The Centroid structure
The mountain plot representation
Aptamer information
Type Detail Type Detail
Aptamer ID Apta_235 Description 4.4.20
Aptamer chemistry DNA Length 80 nt
GC content 48.8% Molecular weight 25,050.81 Da
Molarity of 1 μg/μl solution 39.92 μM Number of G-quadruplexes No QGRS found
G-Score N/A Function Targeted binding
Sequence AGCAGCACAGAGGTCAGATGTGGTTCGATGCTGCAAGGTGTTGTCATTTGGCATATGTTACCTATGCGTGCTACCGTGAA
Applications Binding to target human IgG
Target information
Type Detail Type Detail
Target ID Other-52 Name Ig E
Activity data

No relevant experimental diagram

 Interaction ID 240
Target type Other
Target unique ID Other-52
Activity 25 nM
Binding Conditions/Buffer

PBS and 1 mM MgCl2 (pH 8.0)
Assay

N/A
PubMed ID 15362896
Similar aptamers
Aptamer ID Aptamer chemistry Sequence Similarity
Apta_101 DNA AGCAGCACAGAGGTCAGATGTGTTAGGCTGGGACACGTATTACACTTACCGTAAATATTTCCTATGCGTGCTACCGTGAA 76.25%
Apta_102 DNA AGCAGCACAGAGGTCAGATGCGTTTTTTACGGCTGGCAACGGAAGTCAGTTTATTCTTCACCTATGCGTGCTACCGTGAA 76.25%
Apta_101 DNA AGCAGCACAGAGGTCAGATGTGTTAGGCTGGGACACGTATTACACTTACCGTAAATATTTCCTATGCGTGCTACCGTGAA 76.25%
Apta_102 DNA AGCAGCACAGAGGTCAGATGCGTTTTTTACGGCTGGCAACGGAAGTCAGTTTATTCTTCACCTATGCGTGCTACCGTGAA 76.25%
Apta_99 DNA AGCAGCACAGAGGTCAGATGTCGGGCGGTTCGGGACCTTGCTGCGACATATGCGTATTATCCTATGCGTGCTACCGTGAA 75.00%
Apta_99 DNA AGCAGCACAGAGGTCAGATGTCGGGCGGTTCGGGACCTTGCTGCGACATATGCGTATTATCCTATGCGTGCTACCGTGAA 75.00%
Apta_107 DNA AGCAGCACAGAGGTCAGATGTTCATTTCAGTTGACCGATAGCATTGAGCAATGATCTATTCCTATGCGTGCTACCGTGAA 73.75%
Apta_107 DNA AGCAGCACAGAGGTCAGATGTTCATTTCAGTTGACCGATAGCATTGAGCAATGATCTATTCCTATGCGTGCTACCGTGAA 73.75%
Apta_173 DNA AGCAGCACAGAGGTCAGATGGCAGGTTTCGACGTACAATGCTATGGAGGCTTTATGATCGCCTATGCGTGCTACCGTGAA 73.75%
Apta_174 DNA AGCAGCACAGAGGTCAGATGTCGGTCTTGTGTATACATACCCGTGTGTTTTCATCTCAGGCCTATGCGTGCTACCGTGAA 73.75%
Apta_178 DNA AGCAGCACAGAGGTCAGATGCGGTATGCTGGGTCATCTAACTGGGGATATTCTGATATTGCCTATGCGTGCTACCGTGAA 73.75%
Apta_109 DNA AGCAGCACAGAGGTCAGATGTGCGACCACCTGGATAGACGAGGGTAGTAAGGAGTGTGTTCCTATGCGTGCTACCGTGA 72.50%
Apta_110 DNA AGCAGCACAGAGGTCAGATGGTTAGGAAGGTGAATAGGTACGACTGCAGGTCTATCGCAGCCTATGCGTGCTACCGTGAA 72.50%
Apta_109 DNA AGCAGCACAGAGGTCAGATGTGCGACCACCTGGATAGACGAGGGTAGTAAGGAGTGTGTTCCTATGCGTGCTACCGTGA 72.50%
Apta_110 DNA AGCAGCACAGAGGTCAGATGGTTAGGAAGGTGAATAGGTACGACTGCAGGTCTATCGCAGCCTATGCGTGCTACCGTGAA 72.50%
Apta_177 DNA AGCAGCACAGAGGTCAGATGCCATAGGTGCCTGAATTGTCCCAAACATTCGCATGATCGACCTATGCGTGCTACCGTGAA 72.50%
Apta_236 DNA AGCAGCACAGAGGTCAGATGAGATGGTTGACCGGTTGATGTGATTAAGGAGACGTCGATTCCTATGCGTGCTACCGTGAA 72.50%
Apta_104 DNA AGCAGCACAGAGGTCAGATGCAAACCACAGCCTGAGTGGTTAGCGTATGTCATTTACGGACCTATGCGTGCTACCGTGAA 71.25%
Apta_104 DNA AGCAGCACAGAGGTCAGATGCAAACCACAGCCTGAGTGGTTAGCGTATGTCATTTACGGACCTATGCGTGCTACCGTGAA 71.25%
Apta_175 DNA AGCAGCACAGAGGTCAGATGAGGACTGTCGATAAGTATAATGGCAAGTAGCTCGATACATCCTATGCGTGCTACCGTGAA 71.25%

ABOUT

AptaDB is an online database we developed to integrate comprehensive information about aptamer.
The detail of this database is described here:

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