Aptamer-target interaction descriptor
Aptamer-target interaction information
| Aptamer ID | Aptamer descriptor | Target chemistry | Target name | Affinity | Binding Conditions/Buffer | PubMed ID |
|---|---|---|---|---|---|---|
| Apta_829 | P12-31 | Cell | Escherichia Coli (E.Coli) | 87.03 nM | PBS containing 1.4 mM MgCl2 | 27104834 |
Structure information of aptamer
| Aptamer Sequence: | CCCTCCGGGGGGGTCATCGGGATACCTGGTAAGGATA |
| The optimal secondary structure in dot-bracket notation: | .((((((((...(((.....))).)))))..)))... |
| The centroid secondary structure in dot-bracket notation: | ...............((((((...))))))....... |
The MFE structure
The Centroid structure
The mountain plot representation
Aptamer information
| Type | Detail | Type | Detail |
|---|---|---|---|
| Aptamer ID | Apta_829 | Description | P12-31 |
| Aptamer chemistry | DNA | Length | 37 nt |
| GC content | 62.2% | Molecular weight | 11,471.36 Da |
| Molarity of 1 μg/μl solution | 87.17 μM | Number of G-quadruplexes | 2 |
| G-Score | 19 | Function | Aptasensor |
| Sequence | CCCTCCGGGGGGGTCATCGGGATACCTGGTAAGGATA | ||
| Applications | Diagnosis of MNEC-borne pathologies | ||
Target information
| Type | Detail | Type | Detail |
|---|---|---|---|
| ATCC ID | 25922 | Cell name | Escherichia Coli (E.Coli) |
| Category | Bacteria | Organism | N/A |
| Product type | Preceptrol culture | Cell type | N/A |
| Morphology | N/A | Tissue | N/A |
| Disease | N/A | Product format | Freeze-dried |
| Antigen expression | N/A | Genes expressed | N/A |
| Cell description | This strain does not produce verotoxin. This organism is a CLSI control strain for antimicrobial susceptibility testing. Used in susceptibility disc testing of neomycin, colistin [colimycin], kanamycin, cephalexin, gentamicins, cefamandole, cephalothin, tetracycline, cephaloglycin, cephaloridine [cephalomycin], nalidixic acid, and chloramphenicol. |
|
|
| Application(s) | Bioinformatics; Food testing; Media testing; Quality control | ||
Activity data
 |
Interaction ID | 915 |
| Target type | Cell | |
| Target unique ID | 25922 | |
| Activity | 87.03 nM | |
| Binding Conditions/Buffer | PBS containing 1.4 mM MgCl2 |
|
| Assay | Binding affinity of selected pool 12 aptamers to E coli ATCC 25922 |
|
| PubMed ID | 27104834 |
Similar aptamers
| Aptamer ID | Aptamer chemistry | Sequence | Similarity |
|---|---|---|---|
| Apta_517 | DNA | ACCTTCGGGGAGTATTGCGGAGGAAGGT | |
| Apta_258 | DNA | CACTGCGGGGGTCTATACGTGAGGAAGAAGTGGGCAGGTC | |
| Apta_515 | DNA | CCTGGGGGAGTATTGCGGAGGAAGG | |
| Apta_678 | DNA | CGTACGGTGGGAACGGTTCCTCTTAGGGT | |
| Apta_1149 | DNA | ATCATGGTGGGTATCGGCACTCGTTGGTTGAT | |
| Apta_1199 | DNA | CCCTGCGGGGCTGCCCGATATGTGTCCAAGTGGTG | |
| Apta_1199 | DNA | CCCTGCGGGGCTGCCCGATATGTGTCCAAGTGGTG | |
| Apta_1199 | DNA | CCCTGCGGGGCTGCCCGATATGTGTCCAAGTGGTG | |
| Apta_1199 | DNA | CCCTGCGGGGCTGCCCGATATGTGTCCAAGTGGTG | |
| Apta_1208 | DNA | CCCTGCGGGGCTGCCCGATATGTGTCCAGGTGGTG | |
| Apta_693 | DNA | CGAGTTGAGCCGGGCGCGGTACGGGTACTGGTATGTGTGG | |
| Apta_1095 | DNA | CCCTGAGGGGTGATGTGAATCCTAACAGTAAGGAGGAAGG | |
| Apta_8 | DNA | TGTGGGGGTGGACGGGCCGGGTAGA | |
| Apta_16 | DNA | AGGGGGGGGGGACGGGACGGGTATA | |
| Apta_28 | DNA | AGTGGGGGGGGTGGAGCCGGGTAGA | |
| Apta_320 | DNA | GCACTCTGTGGGGGTGGACGGGCCGGGT | |
| Apta_552 | DNA | CACCTGGGGGAGTATTGCGGAGGAAGGTTCCAGGTG | |
| Apta_1203 | DNA | CCCTGCGGGGCTACCCGATATGTGTCCGAGTGGTG | |
| Apta_160 | DNA | CGGTGCAGTGGATACATGCCAGCCGTAGCCATCGTGGATA | |
| Apta_879 | DNA | GGGGGGGTGAGACATCGGGCATGTTCATGGGTGGGGGGTA |
DEV TOOL
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