Aptamer-target interaction descriptor
Aptamer-target interaction information
Interaction ID: 1199
Aptamer sequence: AATAGGGTAAAAAAAAAAAGTTGGTCCTATG
Target unique ID: 186907
Aptamer ID Aptamer descriptor Target chemistry Target name Affinity Binding Conditions/Buffer PubMed ID
Apta_1139 A04T.2 Molecule Aflatoxin B1 33 μM 20 mM Tris-HCl, 10 mM (NH4)2SO4, 10 mM KCl 30085205
Structure information of aptamer
Aptamer Sequence: AATAGGGTAAAAAAAAAAAGTTGGTCCTATG
The optimal secondary structure in dot-bracket notation: .((((((.................)))))).
The centroid secondary structure in dot-bracket notation: .((((((.................)))))).
The MFE structure
The Centroid structure
The mountain plot representation
Aptamer information
Type Detail Type Detail
Aptamer ID Apta_1139 Description A04T.2
Aptamer chemistry DNA Length 31 nt
GC content 29.0% Molecular weight 9,648.29 Da
Molarity of 1 μg/μl solution 103.65 μM Number of G-quadruplexes No QGRS found
G-Score N/A Function Targeted binding
Sequence AATAGGGTAAAAAAAAAAAGTTGGTCCTATG
Applications Binding to targets
Target information
Type Detail Type Detail
PubChem ID 186907 Molecular name Aflatoxin B1
Molecular formula C17H12O6 Molecular weight 312.27
IUPAC name (3S,7R)-11-methoxy-6,8,19-trioxapentacyclo[10.7.0.02,9.03,7.013,17]nonadeca-1,4,9,11,13(17)-pentaene-16,18-dione InChIKey OQIQSTLJSLGHID-WNWIJWBNSA-N
LogP 2.277 Topological polar surface area 74.97
Hydrogen bond acceptor 6 Hydrogen bond donor 0

Synonym(s):
AFLATOXIN B1; 1162-65-8; AFB1; UNII-9N2N2Y55MH; NSC-529592; 1H,11H-Cyclopenta[c]furo[3',2':4,5]furo[2,3-h][1]benzopyran-1,11-dione,2,3,6a,9a-tetrahydro-4-methoxy-, (6aR,9aS)-; AFBI; 9N2N2Y55MH; CHEBI:2504; 2,3,6aalpha,9aalpha-Tetrahydro-4-methoxycyclopenta(c)furo(3',2':4,5)furo(2,3-h)(1)benzopyran-1,11-dione; MFCD00869647; (6aR,9aS)-4-methoxy-2,3,6a,9a-tetrahydrocyclopenta[c]furo[3',2':4,5]furo[2,3-h]chromene-1,11-dione; Aflatoxin B; (3S,7R)-11-methoxy-6,8,19-trioxapentacyclo[10.7.0.02,9.03,7.013,17]nonadeca-1,4,9,11,13(17)-pentaene-16,18-dione; NSC 529592; HSDB 3453; NSC529592; CCRIS 12; Aflatoxin B1 2 microg/mL in Acetonitrile; Cyclopenta(c)furo(3',2':4,5)furo(2,3-h)(1)benzopyran-1,11-dione, 2,3,6a,9a-tetrahydro-4-methoxy-; Cyclopenta(c)furo(3',2':4,5)furo(2,3-h)(1)benzopyran-1,11-dione, 2,3,6a,9a-tetrahydro-4-methoxy-, (6aR,9aS)-; EINECS 214-603-3; BRN 1269174; Aflatoxin B1 from Aspergillus flavus, from Aspergillus flavus; (+/-)-Aflatoxin B1; BIDD:ER0313; SCHEMBL126480; Aflatoxin B1 Standard Solution; CHEMBL1697694; DTXSID9020035; Aflatoxin B1, reference material; DTXSID00873175; BDBM120261; ZINC402671; AMY22311; EX-A5480; HY-N6615; AKOS030241596; VA10187; NCGC00247669-01; 2,3,6aalpha,9aalpha-Tetrahydro-4-methoxycyclopenta(c)furo(2',3':4,5)furo(2,3-h)chromene-1,11-dione; Cyclopenta(c)furo(3',2':4,5)furo(2,3-h)(1)benzopyran-1,11-dione, 2,3,6aalpha,9aalpha-tetrahydro-4-methoxy-; CS-0034371; 162A658; Q4689278; WLN: T F5 C6 B655 DOV GV OO QO RUT&&TTJ LO1; Aflatoxin B1 solution, 20 mug/mL in methanol, analytical standard; Aflatoxin B1 solution, 2 mug/mL in acetonitrile, analytical standard; Aflatoxin B1 solution, 3 mug/mL in benzene:acetonitrile (98:2), analytical standard; Aflatoxin B1 solution, 3.79 mug/g in acetonitrile, ERM(R) certified Reference Material; Aflatoxin B1 solution, certified reference material, 20 mug/mL in methanol, ampule of 1 mL; 10279-73-9; Aflatoxin B1 solution, certified reference material, 3 mug/mL in benzene:acetonitrile (98:2), ampule of 1 mL; Cyclopenta[c]furo[3',5]furo[2,3-h][1]benzopyran-1,11-dione, 2,3,6a,9a-tetrahydro-4-methoxy-; Cyclopenta[c]furo[3',5]furo[2,3-h][1]benzopyran-1,11-dione, 2,3,6a,9a-tetrahydro-4-methoxy-, (6aR-cis)-; Cyclopenta[c]furo[3',5]furo[2,3-h][1]benzopyran-1,11-dione, 2,3,6a.alpha.,9a.alpha.-tetrahydro-4-methoxy-

Activity data
Interaction ID 1195
Target type Molecule
Target unique ID 442530
Activity 71 nM
Binding Conditions/Buffer

20 mM Tris-HCl, 10 mM (NH4)2SO4, 10 mM KCl
Assay

Binding isotherms for aptamer
PubMed ID 30085205
Interaction ID 1196
Target type Molecule
Target unique ID 20966
Activity 71 μM
Binding Conditions/Buffer

20 mM Tris-HCl, 10 mM (NH4)2SO4, 10 mM KCl
Assay

Binding isotherms for aptamer
PubMed ID 30085205
Interaction ID 1197
Target type Molecule
Target unique ID 54678486
Activity 1492 nM
Binding Conditions/Buffer

20 mM Tris-HCl, 10 mM (NH4)2SO4, 10 mM KCl
Assay

Binding isotherms for aptamer
PubMed ID 30085205
Interaction ID 1198
Target type Molecule
Target unique ID 54680783
Activity 3918 nM
Binding Conditions/Buffer

20 mM Tris-HCl, 10 mM (NH4)2SO4, 10 mM KCl
Assay

Binding isotherms for aptamer
PubMed ID 30085205
Interaction ID 1199
Target type Molecule
Target unique ID 186907
Activity 33 μM
Binding Conditions/Buffer

20 mM Tris-HCl, 10 mM (NH4)2SO4, 10 mM KCl
Assay

Binding isotherms for aptamer
PubMed ID 30085205
Similar aptamers
Aptamer ID Aptamer chemistry Sequence Similarity
Apta_419 DNA ATCAGGGCTAAAGAGTGCAGAGTTACTTAG 54.84%
Apta_1152 DNA GACAAGGATAAATCCTTCAATGAAGTGGGTCACTCATCTGTGA 53.49%
Apta_929 DNA GAGTGGGATGGATAGAGAATAAGTGTGGAGTGGAAGGTGA 52.50%
Apta_343 DNA AACAGAGGGACAAACGGGGGAAGATTTGACGTCGACGAC 51.28%
Apta_847 DNA CACTAGGATCTAGGGAAAAATCTCGTAAATACTATACTCCTGAGC 51.11%
Apta_261 DNA TAAACCCCAAAACAGTGCAACTAGGTGTAGGTCCCGTGGT 50.00%
Apta_512 DNA ATAGGACGATTATCGAAAATCACCAGATTGGACCCTGGTTAACGAT 50.00%
Apta_580 DNA ATGCGGGTATATGGTGCGAGAAAACAAGGGGCATACTGGA 50.00%
Apta_783 DNA AAGGGGTTGGGTGGGTTTATACAAATTAATTAATATTGTATGGTATATTT 50.00%
Apta_876 DNA GTTGCGAAAGACAACGAATGCTTTGCCTGCCATAATTTGC 50.00%
Apta_946 DNA TACCGGGTAATATGCACACATGCTGATAGCAAGCAATGCA 50.00%
Apta_977 DNA CAATCTGCTAAAACTTAAAGCCTATTAATGAAATTGTTAAGGTGGTATCC 50.00%
Apta_1286 DNA CTATACGTATTCTAACTTGTTACGTATTGGTCTCTTATTG 50.00%
Apta_639 DNA CTAAGCACAGGGAAACCAGCTAATGAGTTAGGCCTGTCCCCCACG 48.89%
Apta_640 DNA CAATGGACCTATTCGAGTACTGAATAGAACAGTCGGCGCTCTGGG 48.89%
Apta_158 DNA CACAGGCTACGGCACGTAGAGCATCACCATGATCCTGTG 48.72%
Apta_347 DNA AAAAAAAAAAAAGTACGTTCAGGAGCAGTGCGA 48.48%
Apta_213 DNA AGGAAGGCAAAAGGAAAAAAAAAAAGGAAA 48.39%
Apta_330 DNA GCTGGGTAAATAGATGATTCCCGGC 48.39%
Apta_514 DNA ACTCAGCACGCGTGTAGGGAAAACCAACCGCCCACAAGCTGCATGCAACG 48.00%

ABOUT

AptaDB is an online database we developed to integrate comprehensive information about aptamer.
The detail of this database is described here:

HELP CENTER

>Contact us
>LMMD Group
>School of Pharmacy

DEV TOOL
Page last updated at 2022-05-25 10:01:57 (Asia/Shanghai) | You are visitor No. 43982
Copyright © 2019-2020 Laboratory of Molecular Modeling and Design, School of Pharmacy, East China University of Science and Technology. All rights reserved.