Aptamer-target interaction descriptor
Aptamer-target interaction information
| Aptamer ID | Aptamer descriptor | Target chemistry | Target name | Affinity | Binding Conditions/Buffer | PubMed ID |
|---|---|---|---|---|---|---|
| Apta_806 | Aptamer17a | Cell | PC12 Cells | 10 μM | (5 mM MgCl in PBS) from and 1 mg/ml yeast tRNA for 30 minutes | 21749299 |
Structure information of aptamer
| Aptamer Sequence: | GGTTGGATGTAAGGTTGGAGGGGGG |
| The optimal secondary structure in dot-bracket notation: | ..((.(((.....))).))...... |
| The centroid secondary structure in dot-bracket notation: | ..((.(((.....))).))...... |
The MFE structure
The Centroid structure
The mountain plot representation
Aptamer information
| Type | Detail | Type | Detail |
|---|---|---|---|
| Aptamer ID | Apta_806 | Description | Aptamer17a |
| Aptamer chemistry | DNA | Length | 25 nt |
| GC content | 60.0% | Molecular weight | 7,954.11 Da |
| Molarity of 1 μg/μl solution | 125.72 μM | Number of G-quadruplexes | 2 |
| G-Score | 20 | Function | Target recognition |
| Sequence | GGTTGGATGTAAGGTTGGAGGGGGG | ||
| Applications | Recognition of differentiated PC12 cells | ||
Target information
| Type | Detail | Type | Detail |
|---|---|---|---|
| ATCC ID | CRL-1721 | Cell name | PC12 Cells |
| Category | Animal cells | Organism | Rattus norvegicus, rat |
| Product type | N/A | Cell type | N/A |
| Morphology | small irregularly shaped cells | Tissue | Adrenal gland |
| Disease | Pheochromocytoma | Product format | Frozen |
| Antigen expression | N/A | Genes expressed | Catecholamines: dopamine; norepinephrine |
| Cell description | PC-12 is a cell line that was derived from a transplantable rat pheochromocytoma. This cell line can be used in neuroscience and toxicology research. |
|
|
| Application(s) | 3D cell culture; High-throughput screening; Neuroscience; Toxicology | ||
Activity data
|
No relevant experimental diagram |
Interaction ID | 892 |
| Target type | Cell | |
| Target unique ID | CRL-1721 | |
| Activity | 10 μM | |
| Binding Conditions/Buffer | (5 mM MgCl in PBS) from and 1 mg/ml yeast tRNA for 30 minutes |
|
| Assay | N/A |
|
| PubMed ID | 21749299 |
Similar aptamers
| Aptamer ID | Aptamer chemistry | Sequence | Similarity |
|---|---|---|---|
| Apta_1193 | DNA | GGGTTGGAGGTGGAGGGGAGTTGAGG | |
| Apta_757 | DNA | GGTGGTGGTGGTTGTGGTGGTGG | |
| Apta_350 | DNA | GGTGGTGGTGGTTGTGGTGGTGGTGG | |
| Apta_1195 | DNA | GGGGTTGGGGGGAGGCGGGGAATGGGGG | |
| Apta_211 | DNA | GGTTGGTGTGGTTGG | |
| Apta_483 | DNA | ATTGGGAGGGATTGGGTGGG | |
| Apta_929 | DNA | GAGTGGGATGGATAGAGAATAAGTGTGGAGTGGAAGGTGA | |
| Apta_63 | DNA | GACCCGTGGTAGGGTAGGATGGGGTGGTC | |
| Apta_65 | DNA | CTACCGTGGTAGGGAAGGTTGGAGTGTAG | |
| Apta_646 | DNA | TGGAGCTTGGATTGATGTGGTGTGTGAGTGCGGTGCCC | |
| Apta_203 | DNA | GGAAGGCTTTAGGTCTGAGATCTCGG | |
| Apta_46 | DNA | CGGGTGGGAGTTGTGGGGGGGGGTGGGAGGGTT | |
| Apta_1094 | DNA | GGAATCGTGGGTGGTAGGGTAGGGGATGCA | |
| Apta_1241 | DNA | GGTGTGGAGTGGTGTGTGTTGTTGTTTGTC | |
| Apta_1243 | DNA | GGTGTTGTTGTTGGCTAGTTTGTTGTGGGC | |
| Apta_1247 | DNA | GGTGGTTGCTGTTGTTTGTGGTTGGTGTGC | |
| Apta_1062 | DNA | GGGGTCTTGCAGGTCCCGTAGGAGGGGCCATTGGAGTGGGG | |
| Apta_10 | DNA | GGGGGGGGTGGCTGGGCGGGGTGGG | |
| Apta_12 | DNA | TGAGGGGGTGGGTGGGACGGGTTGG | |
| Apta_13 | DNA | AGGGGGGGGGGAGGGGTCGGGGTGG |
DEV TOOL
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