Aptamer-target interaction descriptor
Aptamer-target interaction information
Interaction ID: 718
Aptamer sequence: GGAUAAUAGCCGUAGGUUGCGAAAGCGACCCUGAUGAGAAAGCCAAAGCCGUAGCGCAGAUGAUCUCGCCAUCAGUACCGAAACGGUAGCGAGAGCUC
Target unique ID: 23930
Aptamer ID Aptamer descriptor Target chemistry Target name Affinity Binding Conditions/Buffer PubMed ID
Apta_563 AR1 Molecule Manganese (II) ion 100 μM 50 mM Tris-HCl, pH 7.5, 20 mM MgCl2 11283591
Structure information of aptamer
Aptamer Sequence: GGAUAAUAGCCGUAGGUUGCGAAAGCGACCCUGAUGAGAAAGCCAAAGCCGUAGCGCAGAUGAUCUCGCCAUCAGUACCGAAACGGUAGCGAGAGCUC
The optimal secondary structure in dot-bracket notation: ........(((((.((((((....))))))((((((.....((....))....(((.(((...)))))))))))).......)))))(((....))).
The centroid secondary structure in dot-bracket notation: ..............((((((....))))))((((((.....((....))....(((.((.....))))))))))).(((.....))).((....))..
The MFE structure
The Centroid structure
The mountain plot representation
Aptamer information
Type Detail Type Detail
Aptamer ID Apta_563 Description AR1
Aptamer chemistry RNA Length 98 nt
GC content 54.1% Molecular weight 31,742.02 Da
Molarity of 1 μg/μl solution 31.50 μM Number of G-quadruplexes No QGRS found
G-Score N/A Function Aptasensor
Sequence GGAUAAUAGCCGUAGGUUGCGAAAGCGACCCUGAUGAGAAAGCCAAAGCCGUAGCGCAGAUGAUCUCGCCAUCAGUACCGAAACGGUAGCGAGAGCUC
Applications Recognition of cAMP
Target information
Type Detail Type Detail
PubChem ID 23930 Molecular name Manganese (II) ion
Molecular formula Mn Molecular weight 54.94
IUPAC name manganese InChIKey PWHULOQIROXLJO-UHFFFAOYSA-N
LogP -0.003 Topological polar surface area 0
Hydrogen bond acceptor 0 Hydrogen bond donor 0

Synonym(s):
7439-96-5; Manganese; Mn; Colloidal manganese; Mangan; Manganese, elemental; manganide; Manganese metal alloy; Manganese fume; manganese(4+); Manganese metal; UNII-42Z2K6ZL8P; Manganese(1-); Manganese, ion (Mn1-); MANGANESE (II) ION; 42Z2K6ZL8P; Manganese powder; MFCD00011111; Cutaval; Magnacat; Tronamang; Mangan [Polish]; MANGANESE COMPOUNDS; Manganese powder, -325 mesh; manganeso; Teprosyn M; Manganese element; Mangan nitridovany; Mangan nitridovany [Czech]; Manganese-55; Manganese(4 ); Manganese(7+); CCRIS 1579; HSDB 550; Manganese ion(4 ); EINECS 231-105-1; Manganese, ion (Mn4 ); MNE 06PB; manganum; manganese atom; Manganese, ion (Mn(7+)); Manganese chips; manganese(0); manganese (IV); manganide(-I); manganese (0); manganide(1-); MN3; manganese(4+) ion; Manganese, 99%; manganese(IV) cation; Manganese fume, as Mn; Manganese fume (as Mn); Mn(IV); Manganese, -200 mesh; 25Mn; EC 231-105-1; Manganese pieces, irregular; Manganese compounds, n.o.s.; Mn(-); Mn(0); Manganese, metal, electrolytic; DTXSID2024169; CHEBI:18291; CHEBI:25158; CHEBI:33011; CHEBI:35154; HSDB 6945; Mn(4+); Manganese powder, APS <10 micron; Manganese nanopowder, APS 30-50nm; Manganese powder, -140+325 mesh; AKOS015833390; Manganese powder, 99.9% (metal basis); Mn4; S618; Manganese pieces, 10mm & down, ultrapure; FT-0689227; Manganese, chips, thickness <2.0 mm, 99%; C00034; Manganese granules, 0.8-3mm (0.03-0.12in); Manganese, powder, >=99.9% trace metals basis; Q27109868; Q27115185; M008000000; Manganese powder , -325 mesh, =99% trace metals basis; Manganese, rod, 10mm, diameter 4.0mm, cast, 99.5%; Manganese, rod, 35mm, diameter 2.0mm, cast, 99.5%; Manganese, rod, 47mm, diameter 2.0mm, cast, 99.5%; Manganese, rod, 50mm, diameter 4.0mm, cast, 99.5%; Manganese, rod, 50mm, diameter 6.35mm, cast, 99.5%; Manganese, flake, 25 mm, weight 100 g, purity 99.95%; Manganese, flake, 25 mm, weight 50 g, purity 99.95%; Manganese, flake, weight 200 g, 25 mm, purity 99.95%; Manganese, plasma standard solution, Specpure, Mn 10g/ml; Manganese, powder, -325 mesh, >=99% trace metals basis; Manganese, AAS standard solution, Specpure?, Mn 1000?g/ml; Manganese, Oil based standard solution, Specpure, Mn 5000g/g; Manganese, plasma standard solution, Specpure?, Mn 1000?g/ml; Manganese, foil, 25x25mm, thickness 2mm, hot-pressed, 99.95%; Manganese, foil, 50x50mm, thickness 2mm, hot-pressed, 99.95%; Manganese, Oil based standard solution, Specpure?, Mn 1000?g/g; Manganese, plasma standard solution, Specpure?, Mn 10,000?g/ml; Manganese, rod, 2.0 mm diameter, length 52 mm, purity 99.5%; Manganese, rod, length 25 mm, 2.0 mm diameter, purity 99.5%; Manganese standard for AAS, ready-to-use, traceable to BAM, in nitric acid; Manganese, foil, thickness 0.016 mm, size 25 x 25 mm, purity 98.7%; Manganese, foil, thickness 0.016 mm, size 50 x 50 mm, purity 98.7%; Manganese sputtering target, 50.8mm (2.0in) dia x 3.18mm (0.125in) thick; Manganese sputtering target, 50.8mm (2.0in) dia x 6.35mm (0.250in) thick; Manganese sputtering target, 76.2mm (3.0in) dia x 3.18mm (0.125in) thick; Manganese sputtering target, 76.2mm (3.0in) dia x 6.35mm (0.250in) thick; Manganese standard for IC, certified reference material, ready-to-use, traceable to BAM; Manganese standard for ICP, for ICP, ready-to-use, traceable to BAM, in nitric acid; Manganese, powder, 300 max. part. size (micron), weight 1000 g, purity 99.5%; Manganese, powder, 300 max. part. size (micron), weight 2000 g, purity 99.5%; Manganese, powder, 45 max. part. size (micron), weight 2000 g, purity 99.5%; Manganese, powder, max. particle size 300 micron, weight 100 g, purity 99.5%; Manganese, powder, max. particle size 300 micron, weight 200 g, purity 99.5%; Manganese, powder, max. particle size 300 micron, weight 500 g, purity 99.5%; Manganese, powder, max. particle size 45 micron, weight 100 g, purity 99.5%; Manganese, powder, max. particle size 45 micron, weight 1000 g, purity 99.5%; Manganese, powder, max. particle size 45 micron, weight 200 g, purity 99.5%; Manganese, powder, max. particle size 45 micron, weight 500 g, purity 99.5%; Manganese, foil, not light tested, 100x100mm, thickness 0.0125mm, permanent polyester support, 98.7%; Manganese, foil, not light tested, 100x100mm, thickness 0.015mm, permanent polyester support, 98.7%; Manganese, foil, not light tested, 100x100mm, thickness 0.01mm, permanent polyester support, 98.7%; Manganese, foil, not light tested, 100x100mm, thickness 0.025mm, permanent polyester support, 98.7%; Manganese, foil, not light tested, 100x100mm, thickness 0.02mm, permanent polyester support, 98.7%; Manganese, foil, not light tested, 25x25mm, thickness 0.001mm, permanent polyester support, 98.7%; Manganese, foil, not light tested, 25x25mm, thickness 0.0025mm, permanent polyester support, 98.7%; Manganese, foil, not light tested, 25x25mm, thickness 0.002mm, permanent polyester support, 98.7%; Manganese, foil, not light tested, 25x25mm, thickness 0.003mm, permanent polyester support, 98.7%; Manganese, foil, not light tested, 25x25mm, thickness 0.004mm, permanent polyester support, 98.7%; Manganese, foil, not light tested, 25x25mm, thickness 0.005mm, permanent polyester support, 98.7%; Manganese, foil, not light tested, 25x25mm, thickness 0.006mm, permanent polyester support, 98.7%; Manganese, foil, not light tested, 25x25mm, thickness 0.007mm, permanent polyester support, 98.7%; Manganese, foil, not light tested, 25x25mm, thickness 0.008mm, permanent polyester support, 98.7%; Manganese, foil, not light tested, 25x25mm, thickness 0.009mm, permanent polyester support, 98.7%; Manganese, foil, not light tested, 25x25mm, thickness 0.0125mm, permanent polyester support, 98.7%; Manganese, foil, not light tested, 25x25mm, thickness 0.015mm, permanent polyester support, 98.7%; Manganese, foil, not light tested, 25x25mm, thickness 0.01mm, permanent polyester support, 98.7%; Manganese, foil, not light tested, 25x25mm, thickness 0.025mm, permanent polyester support, 98.7%; Manganese, foil, not light tested, 25x25mm, thickness 0.02mm, permanent polyester support, 98.7%; Manganese, foil, not light tested, 25x25mm, thickness 0.05mm, permanent polyester support, 98.7%; Manganese, foil, not light tested, 50x50mm, thickness 0.001mm, permanent polyester support, 98.7%; Manganese, foil, not light tested, 50x50mm, thickness 0.0025mm, permanent polyester support, 98.7%; Manganese, foil, not light tested, 50x50mm, thickness 0.002mm, permanent polyester support, 98.7%; Manganese, foil, not light tested, 50x50mm, thickness 0.003mm, permanent polyester support, 98.7%; Manganese, foil, not light tested, 50x50mm, thickness 0.004mm, permanent polyester support, 98.7%; Manganese, foil, not light tested, 50x50mm, thickness 0.005mm, permanent polyester support, 98.7%; Manganese, foil, not light tested, 50x50mm, thickness 0.006mm, permanent polyester support, 98.7%; Manganese, foil, not light tested, 50x50mm, thickness 0.007mm, permanent polyester support, 98.7%; Manganese, foil, not light tested, 50x50mm, thickness 0.008mm, permanent polyester support, 98.7%; Manganese, foil, not light tested, 50x50mm, thickness 0.009mm, permanent polyester support, 98.7%; Manganese, foil, not light tested, 50x50mm, thickness 0.0125mm, permanent polyester support, 98.7%; Manganese, foil, not light tested, 50x50mm, thickness 0.015mm, permanent polyester support, 98.7%; Manganese, foil, not light tested, 50x50mm, thickness 0.01mm, permanent polyester support, 98.7%; Manganese, foil, not light tested, 50x50mm, thickness 0.025mm, permanent polyester support, 98.7%; Manganese, foil, not light tested, 50x50mm, thickness 0.02mm, permanent polyester support, 98.7%; Manganese, foil, not light tested, 50x50mm, thickness 0.05mm, permanent polyester support, 98.7%

Activity data

No relevant experimental diagram

Interaction ID 596
Target type Molecule
Target unique ID 23973
Activity 100 μM
Binding Conditions/Buffer

50 mM Tris-HCl, pH 7.5, 20 mM MgCl2

Assay

N/A

PubMed ID 11283591

No relevant experimental diagram

Interaction ID 619
Target type Molecule
Target unique ID 104730
Activity 100 μM
Binding Conditions/Buffer

50 mM Tris-HCl, pH 7.5, 20 mM MgCl2

Assay

N/A

PubMed ID 11283591

No relevant experimental diagram

Interaction ID 718
Target type Molecule
Target unique ID 23930
Activity 100 μM
Binding Conditions/Buffer

50 mM Tris-HCl, pH 7.5, 20 mM MgCl2

Assay

N/A

PubMed ID 11283591

No relevant experimental diagram

Interaction ID 726
Target type Molecule
Target unique ID 935
Activity 100 μM
Binding Conditions/Buffer

50 mM Tris-HCl, pH 7.5, 20 mM MgCl2

Assay

N/A

PubMed ID 11283591

No relevant experimental diagram

Interaction ID 805
Target type Molecule
Target unique ID 23994
Activity 100 μM
Binding Conditions/Buffer

50 mM Tris-HCl, pH 7.5, 20 mM MgCl2

Assay

N/A

PubMed ID 11283591
Similar aptamers
Aptamer ID Aptamer chemistry Sequence Similarity
Apta_710 RNA GGAUAAUAGCCGUAGGUUGCGAAAGCGACCCUGAUGAGUCUGGAUACCAUGCAUGAUGCACCUUGGCAGUCUUACGAAACGGUAGCGAGAGCUC 79.59%
Apta_561 RNA GGAUAAUAGCCGUAGGUUGCGAAAGCGACCCUGAUGAGCCUGUGGAAACAGACGUGGCACAUGACUACGUCGAAACGGUAGCGAGAGCUC 78.57%
Apta_566 RNA GGAUAAUAGCCGUAGGUUGCGAAAGCGACCCUGAUGAGCCCUGCGAUGCAGAAAGGUGCUGACGACACAUCGAAACGGUAGCGAGAGCUC 77.55%
Apta_613 RNA GGAUAAUAGCCGUAGGUUGCGAAAGCGACCCUGAUGAGCCUUAGGAUAUGCAUGAUGCAGAAGGACGUCGAAACGGUAGCGAGAGCUC 77.55%
Apta_562 RNA GGAUAAUAGCCGUAGGUUGCGAAAGCGACCCUGAUGAGCCUUUAGGGCCAAGUGUGGUGAAAGACACACUCGAAACGGUAGCGAGAGCUC 76.53%
Apta_874 RNA GGAUAAUAGCCGUAGGUUGCGAAAGCGACCCUGAUGAGCCUUAGGAUAUGUCUGGAUACCAUGCAUGAUGCACCUUGGCAGUCUUACAGAAGGACGUCGAAACGGUAGCGAGAGCUC 73.50%
Apta_295 RNA AUACCAGCUUAUUCAAUUGCCUGAAAAGCUAUCGCCCAAUUCGCAGUGAUAUCCUUUAAGAUAGUAAGUGCAAUCU 56.12%
Apta_416 RNA GGACCUCGGCGAAAGCCGGUAACGCCACAAGUCGGAGGGUAAGAUCUGACAGGAACUGGGUGACGGAGGUUAGGUGC 54.08%
Apta_429 RNA GCAUGCAGUGUCUAUUCUCGAGUAGCGAUCGUUGAAGGGGUAUAAGGUUGGCAGAUCGCUAGCAUGCAACUGACUCGGAUAAGCA 54.08%
Apta_766 RNA GGUUACCAGCCUUCACUGCGGACGGACAGAGAGUGCAACCUGCCGUGCCGCACCACGGUCGGUCACAC 54.08%
Apta_301 RNA AUACCAGCUUAUUCAAUUGCCUGAAAAGUUGAACUCCAAAUACGCGCUGAGAUAGUAAGUGCAAUCU 53.06%
Apta_551 RNA GGAUGUCCAGUCGCUUGCAAUGCCCUUUUAGACCCUGAUGAGCGGUGCUAGUUAGUUGCAGUUUCGGUUGUUACGCGAAACGGUGAAAGCCGUAGGUCU 52.53%
Apta_157 RNA GGGUUCACUGCAGACUUGACGAAGCUUACAAACAAGAGCAAAAAGGGAGUUGACGUAGACUGUGCGGAAUGGAUCCACAUCUACGAAUUC 52.04%
Apta_294 RNA AUACCAGCUUAUUCAAUUGCCUGAUUAGCGGUAUCACGAUUACUUACCUUCGUUGCUGAGAUAGUAAGUGCAAUCU 52.04%
Apta_297 RNA AUACCAGCUUAUUCAAUUGCCUGAGUAGCUGGGUCCGUCCCCACACAUUACCAUUUGUAGAUAGUAAGUGCAAUCU 52.04%
Apta_353 RNA GAAUUCCGCGUGUGCCAGCGAAAGUUGCGUAUGGGUCACAUCGCAGGCACAUGUCAUCUGGGCGGUCCGUUCGGGAUCC 52.04%
Apta_499 RNA GGACGCGUGGUACCAGGCCGAUCUAUGGACGCUAUAGGCACACCGGAUACUUUAACGAUUGGCUAAGCUUCCGCGGGGAUC 52.04%
Apta_690 RNA GGGCGAAUUCCCGAGGACCAAAUAGUACCACCCGGGAAAACAGCUAAUGCCGAAACGGAGAUUUUUUCUGCAGAAGCU 52.04%
Apta_280 RNA GAUAAUACGACUCACUAUAGGGUUCACUGCAGACUUGACGAAGCUUGCAGAAAAGGGGGAAGAAGAGGGUGAUUCAGGCGAGAGAAUGGAUCCACAUCUACGAAUUC 51.40%
Apta_123 RNA GGGAGAAAGGGAAGCUUGAGCAGCAGGAGGGCCGGCGUUAGGGUUAGCGAGCCGAUUGAAAGAAGAAGGAACGAGCGUACGGAUCCGAUC 51.02%