Aptamer-target interaction descriptor
Aptamer-target interaction information
Interaction ID: 766
Aptamer sequence: AAGCTTTTTTGACTGACTGCAGCGATTCTTGATCGCCACGGTCTGGAAAAAGAG
Target unique ID: 4790
Aptamer ID Aptamer descriptor Target chemistry Target name Affinity Binding Conditions/Buffer PubMed ID
Apta_622 SS4-54 Molecule Phorate 1.43 μM 300 mM NaCl, 50 mM KCl, 10 mM MgCl2, 50 mM Tris/HCl, and pH 8.3 22261866
Structure information of aptamer
Aptamer Sequence: AAGCTTTTTTGACTGACTGCAGCGATTCTTGATCGCCACGGTCTGGAAAAAGAG
The optimal secondary structure in dot-bracket notation: ...(((((((....(((((..((((((...))))))..)))))..)))))))..
The centroid secondary structure in dot-bracket notation: ...(((((((....(((((..((((((...))))))..)))))..)))))))..
The MFE structure
The Centroid structure
The mountain plot representation
Aptamer information
Type Detail Type Detail
Aptamer ID Apta_622 Description SS4-54
Aptamer chemistry DNA Length 54 nt
GC content 46.3% Molecular weight 16,675.71 Da
Molarity of 1 μg/μl solution 59.97 μM Number of G-quadruplexes No QGRS found
G-Score N/A Function Aptasensor
Sequence AAGCTTTTTTGACTGACTGCAGCGATTCTTGATCGCCACGGTCTGGAAAAAGAG
Applications Analysis and neutralization of the residues of the four organophosphorus pesticides
Target information
Type Detail Type Detail
PubChem ID 4790 Molecular name Phorate
Molecular formula C7H17O2PS3 Molecular weight 260.4
IUPAC name diethoxy-(ethylsulfanylmethylsulfanyl)-sulfanylidene-lambda5-phosphane InChIKey BULVZWIRKLYCBC-UHFFFAOYSA-N
LogP 3.728 Topological polar surface area 18.46
Hydrogen bond acceptor 5 Hydrogen bond donor 0

Synonym(s):
phorate; Thimet; 298-02-2; Granutox; Agrimet; Timet; Thimenox; Geomet; Vegfru; Thimet 10G; Vegfru foratox; American cyanamid 3,911; Thimet 10-G; Foraat; Phorat; VUAgT 182; O,O-Diethyl S-ethylmercaptomethyl dithiophosphate; Rcra waste number P094; Experimental insecticide 3911; Phosphorodithioic acid, O,O-diethyl S-((ethylthio)methyl) ester; ENT 24,042; AC 3911; O,O-Diethyl S-(ethylthio)methyl phosphorodithioate; Phosphorodithioic acid, O,O-diethyl S-[(ethylthio)methyl] ester; UNII-3W54X3W9IV; EI3911; L 11/6; O,O-Diethyl ethylthiomethyl phosphorodithioate; O,O-Diethyl S-ethylthiomethyl dithiophosphonate; O,O-Diethyl S-ethylthiomethyl thiothionophosphate; phosphatidylcholine O-34:2; O,O-Dietil-S-(etiltio-metil)-ditiofosfato; 3W54X3W9IV; CHEBI:38764; O,O-Diethyl-S-(ethylthio-methyl)-dithiofosfaat; O,O-Diaethyl-S-(aethylthio-methyl)-dithiophosphat; Dithiophosphate de O,O-diethyle et D'ethylthiomethyle; o,o-Diethyl S-[(ethylsulfanyl)methyl] dithiophosphate; O,O-diethyl S-[(ethylsulfanyl)methyl] phosphorodithioate; Phorat [German]; Foraat [Dutch]; Phorate-10G; Caswell No. 660; Thimet G; Phorate [ANSI:BSI:ISO]; Phorate 10G; CCRIS 2747; Thimet 10 G; HSDB 1183; EINECS 206-052-2; RCRA waste no. P094; EPA Pesticide Chemical Code 057201; BRN 1708517; Thimate; Volphor; Forate; AI3-24042; diethoxy-(ethylsulfanylmethylsulfanyl)-sulfanylidene-?^{5}-phosphane; Vegfru foratox.; O,O-Diethyl S-ethylmercaptomethyl dithiophosphonate; O,O-Diethyl-S-((ethylthio)methyl)phosphorodithioate; O,O-Dietil-S-(etiltio-metil)-ditiofosfato [Italian]; O,O-Diethyl-S-(ethylthio-methyl)-dithiofosfaat [Dutch]; Spectrum_001801; O,O-Diaethyl-S-(aethylthio-methyl)-dithiophosphat [German]; SpecPlus_000392; Dithiophosphate de O,O-diethyle et d'ethylthiomethyle [French]; Spectrum2_001860; Spectrum3_000816; Spectrum4_000656; Spectrum5_001942; O,O-Diethyl S-ethylthiomethyl dithiophosphate; Methanethiol, (ethylthio)-, S-ester with O,O-diethyl phosphorodithioate; Methanethiol, (ethylthio)-, S-ester with O,O-diethylphosphorodithioate; DSSTox_CID_12459; DSSTox_RID_78949; DSSTox_GSID_32459; SCHEMBL26312; BSPBio_002311; KBioGR_001031; KBioSS_002294; O,O-Diethyl S-(ethylthiomethyl) phosphorodithioate; DivK1c_006488; SPBio_001680; CHEMBL510014; DTXSID4032459; KBio1_001432; KBio2_002292; KBio2_004860; KBio2_007428; KBio3_001811; Phosphorodithioic acid, O,O-diethyl S-(ethylthio)methyl ester; ZINC2040889; Phorate 100 microg/mL in Methanol; Tox21_300398; CCG-39364; Phorate 10 microg/mL in Cyclohexane; Phorate 1000 microg/mL in Acetone; Phorate 1000 microg/mL in Toluene; Phorate 1000 microg/mL in Methanol; AKOS015898767; Phorate 100 microg/mL in Cyclohexane; NCGC00163889-01; NCGC00163889-02; NCGC00163889-03; NCGC00254280-01; CAS-298-02-2; DB-047653; Phorate, PESTANAL(R), analytical standard; 552-EP2274983A1; 552-EP2275422A1; 552-EP2305662A1; 552-EP2308857A1; C18690; o,o-diethyl s-ethylthiomethyl phosphorodithioate; O,O-diethyl-S-ethylthiomethylphosphorodithioate; 298P022; Q421197; J-017647; O,O-Diethyl S-(ethylthio)methyl phosphorodithioic acid; O,O-Diethyl S-[(ethylthio)methyl] phosphorodithioate; O,O-Diethyl S-[(ethylsulfanyl)methyl] dithiophosphate #; O,O-Diethyl S-[(ethylsulphanyl)methyl] dithiophosphate; O,O-Diethyl S-ethylmercaptomethyl dithiophosphoric acid; O,O-Diethyl S-[(ethylsulfanyl)methyl] dithiophosphoric acid; Phosphorodithioate, O,O-diethyl S-((ethylthio)methyl) ester; O,O-Diethyl S-[(ethylsulphanyl)methyl] dithiophosphoric acid; diethoxy-(ethylsulfanylmethylsulfanyl)-sulfanylidene-lambda5-phosphane; Methanethiol, (ethylthio)-, S-ester with O,O-diethyl phosphorodithioic acid

Activity data
Interaction ID 660
Target type Molecule
Target unique ID 90479
Activity 0.9 μM
Binding Conditions/Buffer

300 mM NaCl, 50 mM KCl, 10 mM MgCl2, 50 mM Tris/HCl, and pH 8.3

Assay

Specifificity of SS2-55 and SS4-54 aptamers

PubMed ID 22261866
Interaction ID 752
Target type Molecule
Target unique ID 14210
Activity 2 μM
Binding Conditions/Buffer

300 mM NaCl, 50 mM KCl, 10 mM MgCl2, 50 mM Tris/HCl, and pH 8.3

Assay

Specifificity of SS2-55 and SS4-54 aptamers

PubMed ID 22261866
Interaction ID 766
Target type Molecule
Target unique ID 4790
Activity 1.43 μM
Binding Conditions/Buffer

300 mM NaCl, 50 mM KCl, 10 mM MgCl2, 50 mM Tris/HCl, and pH 8.3

Assay

Specifificity of SS2-55 and SS4-54 aptamers

PubMed ID 22261866
Interaction ID 770
Target type Molecule
Target unique ID 38779
Activity 1.25 μM
Binding Conditions/Buffer

300 mM NaCl, 50 mM KCl, 10 mM MgCl2, 50 mM Tris/HCl, and pH 8.3

Assay

Specifificity of SS2-55 and SS4-54 aptamers

PubMed ID 22261866
Similar aptamers
Aptamer ID Aptamer chemistry Sequence Similarity
Apta_621 DNA AAGCTTGCTTTATAGCCTGCAGCGATTCTTGATCGGAAAAGGCTGAGAGCTACGC 67.27%
Apta_510 DNA TGTAATTTGTCTGCAGCGGTTCTTGATCGCTGACACCATATTATGAAGA 61.11%
Apta_1061 DNA TATTTATTGAATGCTGTAATTTCGCCACGCGAAAGTAGG 59.26%
Apta_340 DNA TACTCAGGGCACTGCAAGCAATTGTGGTCCCAATGGGCTGAGTA 51.85%
Apta_348 DNA ACTTGCTCTGATGCGACAACCTTTTGCCCAGATAGTAAGT 51.85%
Apta_489 DNA GGGGTTAAATATTCCCACATTGCCTGCGCCAGTACAAATAG 51.85%
Apta_912 DNA TAGTATGGACTTGTCTTCTTGTCAGAGTCTGGCAGCACGT 51.85%
Apta_694 DNA ACTCACTATGGAAGAGATGGCGACATCTCTTCTCCGAGCCGGTCGAAATAGTGAGT 51.79%
Apta_451 DNA ATACCAGCTTATTCAATTGAGTAAGAGTGCACTATGTTTTACGAGCCGTTTCCTCGGCAGATAGTAAGTGCAATCT 51.32%
Apta_796 DNA GTGCTGGATGTCACCTCCACTCACCACCTCTTCTCCGCTCCTCGTCATGACACATCCAG 50.85%
Apta_57 DNA GCGGGTCGGTTGCTCGCTTCGCCCGATCGGTCTAAGGGTG 50.00%
Apta_163 DNA GCGCATGACCATTGATGTCTGCACCATCAGAGGCAGAG 50.00%
Apta_259 DNA GCAAGTATGAGCGCAGGAGTTAGGTCCCGTGGCGATGGGT 50.00%
Apta_260 DNA GACGTTAAGCTAGCAGGTGTTAGGTCCCGTGGTGATGAAT 50.00%
Apta_273 DNA ATAAGCTGAGCATCTTAGATCCCCGTCAAGGGCAGCGTAA 50.00%
Apta_274 DNA GATACTGAGCATCGTACATGATCCCGCAACGGGCAGTATT 50.00%
Apta_449 DNA CGCACTATGTTTTACGAGCCGTTTCCTCGGCAGATAGTAAGTGCG 50.00%
Apta_476 DNA CCTATCTTATTCGTTGCGGACTCCCCGGTCGGTATGTATG 50.00%
Apta_776 DNA AGTGGTCGAACTACACATCCTTGAACTGCGGAATTATCTAC 50.00%
Apta_778 DNA GAAGACGAGCGGCGAGTGTTATTACGCTTGGAAACAACCCC 50.00%