| Aptamer ID | Aptamer descriptor | Target chemistry | Target name | Affinity | Binding Conditions/Buffer | PubMed ID |
|---|---|---|---|---|---|---|
| Apta_622 | SS4-54 | Molecule | Phorate | 1.43 μM | 300 mM NaCl, 50 mM KCl, 10 mM MgCl2, 50 mM Tris/HCl, and pH 8.3 | 22261866 |
| Aptamer Sequence: | AAGCTTTTTTGACTGACTGCAGCGATTCTTGATCGCCACGGTCTGGAAAAAGAG |
| The optimal secondary structure in dot-bracket notation: | ...(((((((....(((((..((((((...))))))..)))))..))))))).. |
| The centroid secondary structure in dot-bracket notation: | ...(((((((....(((((..((((((...))))))..)))))..))))))).. |
| Type | Detail | Type | Detail |
|---|---|---|---|
| Aptamer ID | Apta_622 | Description | SS4-54 |
| Aptamer chemistry | DNA | Length | 54 nt |
| GC content | 46.3% | Molecular weight | 16,675.71 Da |
| Molarity of 1 μg/μl solution | 59.97 μM | Number of G-quadruplexes | No QGRS found |
| G-Score | N/A | Function | Aptasensor |
| Sequence | AAGCTTTTTTGACTGACTGCAGCGATTCTTGATCGCCACGGTCTGGAAAAAGAG | ||
| Applications | Analysis and neutralization of the residues of the four organophosphorus pesticides | ||
| Type | Detail | Type | Detail |
|---|---|---|---|
| PubChem ID | 4790 | Molecular name | Phorate |
| Molecular formula | C7H17O2PS3 | Molecular weight | 260.4 |
| IUPAC name | diethoxy-(ethylsulfanylmethylsulfanyl)-sulfanylidene-lambda5-phosphane | InChIKey | BULVZWIRKLYCBC-UHFFFAOYSA-N |
| LogP | 3.728 | Topological polar surface area | 18.46 |
| Hydrogen bond acceptor | 5 | Hydrogen bond donor | 0 |
Synonym(s): phorate; Thimet; 298-02-2; Granutox; Agrimet; Timet; Thimenox; Geomet; Vegfru; Thimet 10G; Vegfru foratox; American cyanamid 3,911; Thimet 10-G; Foraat; Phorat; VUAgT 182; O,O-Diethyl S-ethylmercaptomethyl dithiophosphate; Rcra waste number P094; Experimental insecticide 3911; Phosphorodithioic acid, O,O-diethyl S-((ethylthio)methyl) ester; ENT 24,042; AC 3911; O,O-Diethyl S-(ethylthio)methyl phosphorodithioate; Phosphorodithioic acid, O,O-diethyl S-[(ethylthio)methyl] ester; UNII-3W54X3W9IV; EI3911; L 11/6; O,O-Diethyl ethylthiomethyl phosphorodithioate; O,O-Diethyl S-ethylthiomethyl dithiophosphonate; O,O-Diethyl S-ethylthiomethyl thiothionophosphate; phosphatidylcholine O-34:2; O,O-Dietil-S-(etiltio-metil)-ditiofosfato; 3W54X3W9IV; CHEBI:38764; O,O-Diethyl-S-(ethylthio-methyl)-dithiofosfaat; O,O-Diaethyl-S-(aethylthio-methyl)-dithiophosphat; Dithiophosphate de O,O-diethyle et D'ethylthiomethyle; o,o-Diethyl S-[(ethylsulfanyl)methyl] dithiophosphate; O,O-diethyl S-[(ethylsulfanyl)methyl] phosphorodithioate; Phorat [German]; Foraat [Dutch]; Phorate-10G; Caswell No. 660; Thimet G; Phorate [ANSI:BSI:ISO]; Phorate 10G; CCRIS 2747; Thimet 10 G; HSDB 1183; EINECS 206-052-2; RCRA waste no. P094; EPA Pesticide Chemical Code 057201; BRN 1708517; Thimate; Volphor; Forate; AI3-24042; diethoxy-(ethylsulfanylmethylsulfanyl)-sulfanylidene-?^{5}-phosphane; Vegfru foratox.; O,O-Diethyl S-ethylmercaptomethyl dithiophosphonate; O,O-Diethyl-S-((ethylthio)methyl)phosphorodithioate; O,O-Dietil-S-(etiltio-metil)-ditiofosfato [Italian]; O,O-Diethyl-S-(ethylthio-methyl)-dithiofosfaat [Dutch]; Spectrum_001801; O,O-Diaethyl-S-(aethylthio-methyl)-dithiophosphat [German]; SpecPlus_000392; Dithiophosphate de O,O-diethyle et d'ethylthiomethyle [French]; Spectrum2_001860; Spectrum3_000816; Spectrum4_000656; Spectrum5_001942; O,O-Diethyl S-ethylthiomethyl dithiophosphate; Methanethiol, (ethylthio)-, S-ester with O,O-diethyl phosphorodithioate; Methanethiol, (ethylthio)-, S-ester with O,O-diethylphosphorodithioate; DSSTox_CID_12459; DSSTox_RID_78949; DSSTox_GSID_32459; SCHEMBL26312; BSPBio_002311; KBioGR_001031; KBioSS_002294; O,O-Diethyl S-(ethylthiomethyl) phosphorodithioate; DivK1c_006488; SPBio_001680; CHEMBL510014; DTXSID4032459; KBio1_001432; KBio2_002292; KBio2_004860; KBio2_007428; KBio3_001811; Phosphorodithioic acid, O,O-diethyl S-(ethylthio)methyl ester; ZINC2040889; Phorate 100 microg/mL in Methanol; Tox21_300398; CCG-39364; Phorate 10 microg/mL in Cyclohexane; Phorate 1000 microg/mL in Acetone; Phorate 1000 microg/mL in Toluene; Phorate 1000 microg/mL in Methanol; AKOS015898767; Phorate 100 microg/mL in Cyclohexane; NCGC00163889-01; NCGC00163889-02; NCGC00163889-03; NCGC00254280-01; CAS-298-02-2; DB-047653; Phorate, PESTANAL(R), analytical standard; 552-EP2274983A1; 552-EP2275422A1; 552-EP2305662A1; 552-EP2308857A1; C18690; o,o-diethyl s-ethylthiomethyl phosphorodithioate; O,O-diethyl-S-ethylthiomethylphosphorodithioate; 298P022; Q421197; J-017647; O,O-Diethyl S-(ethylthio)methyl phosphorodithioic acid; O,O-Diethyl S-[(ethylthio)methyl] phosphorodithioate; O,O-Diethyl S-[(ethylsulfanyl)methyl] dithiophosphate #; O,O-Diethyl S-[(ethylsulphanyl)methyl] dithiophosphate; O,O-Diethyl S-ethylmercaptomethyl dithiophosphoric acid; O,O-Diethyl S-[(ethylsulfanyl)methyl] dithiophosphoric acid; Phosphorodithioate, O,O-diethyl S-((ethylthio)methyl) ester; O,O-Diethyl S-[(ethylsulphanyl)methyl] dithiophosphoric acid; diethoxy-(ethylsulfanylmethylsulfanyl)-sulfanylidene-lambda5-phosphane; Methanethiol, (ethylthio)-, S-ester with O,O-diethyl phosphorodithioic acid
|
Interaction ID | 660 |
| Target type | Molecule | |
| Target unique ID | 90479 | |
| Activity | 0.9 μM | |
| Binding Conditions/Buffer | 300 mM NaCl, 50 mM KCl, 10 mM MgCl2, 50 mM Tris/HCl, and pH 8.3 |
|
| Assay | Specifificity of SS2-55 and SS4-54 aptamers |
|
| PubMed ID | 22261866 | |
|
Interaction ID | 752 |
| Target type | Molecule | |
| Target unique ID | 14210 | |
| Activity | 2 μM | |
| Binding Conditions/Buffer | 300 mM NaCl, 50 mM KCl, 10 mM MgCl2, 50 mM Tris/HCl, and pH 8.3 |
|
| Assay | Specifificity of SS2-55 and SS4-54 aptamers |
|
| PubMed ID | 22261866 | |
|
Interaction ID | 766 |
| Target type | Molecule | |
| Target unique ID | 4790 | |
| Activity | 1.43 μM | |
| Binding Conditions/Buffer | 300 mM NaCl, 50 mM KCl, 10 mM MgCl2, 50 mM Tris/HCl, and pH 8.3 |
|
| Assay | Specifificity of SS2-55 and SS4-54 aptamers |
|
| PubMed ID | 22261866 | |
|
Interaction ID | 770 |
| Target type | Molecule | |
| Target unique ID | 38779 | |
| Activity | 1.25 μM | |
| Binding Conditions/Buffer | 300 mM NaCl, 50 mM KCl, 10 mM MgCl2, 50 mM Tris/HCl, and pH 8.3 |
|
| Assay | Specifificity of SS2-55 and SS4-54 aptamers |
|
| PubMed ID | 22261866 |
| Aptamer ID | Aptamer chemistry | Sequence | Similarity |
|---|---|---|---|
| Apta_621 | DNA | AAGCTTGCTTTATAGCCTGCAGCGATTCTTGATCGGAAAAGGCTGAGAGCTACGC | |
| Apta_510 | DNA | TGTAATTTGTCTGCAGCGGTTCTTGATCGCTGACACCATATTATGAAGA | |
| Apta_1061 | DNA | TATTTATTGAATGCTGTAATTTCGCCACGCGAAAGTAGG | |
| Apta_340 | DNA | TACTCAGGGCACTGCAAGCAATTGTGGTCCCAATGGGCTGAGTA | |
| Apta_348 | DNA | ACTTGCTCTGATGCGACAACCTTTTGCCCAGATAGTAAGT | |
| Apta_489 | DNA | GGGGTTAAATATTCCCACATTGCCTGCGCCAGTACAAATAG | |
| Apta_912 | DNA | TAGTATGGACTTGTCTTCTTGTCAGAGTCTGGCAGCACGT | |
| Apta_694 | DNA | ACTCACTATGGAAGAGATGGCGACATCTCTTCTCCGAGCCGGTCGAAATAGTGAGT | |
| Apta_451 | DNA | ATACCAGCTTATTCAATTGAGTAAGAGTGCACTATGTTTTACGAGCCGTTTCCTCGGCAGATAGTAAGTGCAATCT | |
| Apta_796 | DNA | GTGCTGGATGTCACCTCCACTCACCACCTCTTCTCCGCTCCTCGTCATGACACATCCAG | |
| Apta_57 | DNA | GCGGGTCGGTTGCTCGCTTCGCCCGATCGGTCTAAGGGTG | |
| Apta_163 | DNA | GCGCATGACCATTGATGTCTGCACCATCAGAGGCAGAG | |
| Apta_259 | DNA | GCAAGTATGAGCGCAGGAGTTAGGTCCCGTGGCGATGGGT | |
| Apta_260 | DNA | GACGTTAAGCTAGCAGGTGTTAGGTCCCGTGGTGATGAAT | |
| Apta_273 | DNA | ATAAGCTGAGCATCTTAGATCCCCGTCAAGGGCAGCGTAA | |
| Apta_274 | DNA | GATACTGAGCATCGTACATGATCCCGCAACGGGCAGTATT | |
| Apta_449 | DNA | CGCACTATGTTTTACGAGCCGTTTCCTCGGCAGATAGTAAGTGCG | |
| Apta_476 | DNA | CCTATCTTATTCGTTGCGGACTCCCCGGTCGGTATGTATG | |
| Apta_776 | DNA | AGTGGTCGAACTACACATCCTTGAACTGCGGAATTATCTAC | |
| Apta_778 | DNA | GAAGACGAGCGGCGAGTGTTATTACGCTTGGAAACAACCCC |