Aptamer-target interaction descriptor
Aptamer-target interaction information
Interaction ID: 649
Aptamer sequence: GGAUAAUAGCCGUAGGUUGCGAAAGCGACCCUGAUGAGCCUUAGGAUAUGCAUGAUGCAGAAGGACGUCGAAACGGUAGCGAGAGCUC
Target unique ID: 643976
Aptamer ID Aptamer descriptor Target chemistry Target name Affinity Binding Conditions/Buffer PubMed ID
Apta_613 AR5 Molecule Flavin mononucleotide N/A 50 mM Tris-HCl, pH 7.5, 20 mM MgCl2 11283591
Structure information of aptamer
Aptamer Sequence: GGAUAAUAGCCGUAGGUUGCGAAAGCGACCCUGAUGAGCCUUAGGAUAUGCAUGAUGCAGAAGGACGUCGAAACGGUAGCGAGAGCUC
The optimal secondary structure in dot-bracket notation: ........(((((.((((((....)))))).(((((..((((......((((...)))).)))).)))))..)))))(((....))).
The centroid secondary structure in dot-bracket notation: ........(((((.((((((....)))))).(((((..((((......((((...)))).)))).)))))..)))))(((....))).
The MFE structure
The Centroid structure
The mountain plot representation
Aptamer information
Type Detail Type Detail
Aptamer ID Apta_613 Description AR5
Aptamer chemistry RNA Length 88 nt
GC content 52.3% Molecular weight 28,595.09 Da
Molarity of 1 μg/μl solution 34.97 μM Number of G-quadruplexes No QGRS found
G-Score N/A Function Aptasensor
Sequence GGAUAAUAGCCGUAGGUUGCGAAAGCGACCCUGAUGAGCCUUAGGAUAUGCAUGAUGCAGAAGGACGUCGAAACGGUAGCGAGAGCUC
Applications Recognition of FMN
Target information
Type Detail Type Detail
PubChem ID 643976 Molecular name Flavin mononucleotide
Molecular formula C17H21N4O9P Molecular weight 456.3
IUPAC name [(2R,3S,4S)-5-(7,8-dimethyl-2,4-dioxobenzo[g]pteridin-10-yl)-2,3,4-trihydroxypentyl] dihydrogen phosphate InChIKey FVTCRASFADXXNN-SCRDCRAPSA-N
LogP -1.607 Topological polar surface area 208.09
Hydrogen bond acceptor 10 Hydrogen bond donor 6

Synonym(s):
flavin mononucleotide; Riboflavin 5'-phosphate; Riboflavin 5'-monophosphate; RIBOFLAVIN PHOSPHATE; Riboflavin monophosphate; Vitamin B2 phosphate; Riboflavine phosphate; Riboflavin 5'-(dihydrogen phosphate); Flanin; Flavol; Flavine mononucleotide; 146-17-8; Riboflavin mononucleotide; Riboflavine dihydrogen phosphate; FMN; Riboflavine monophosphate; Riboflavine 5'-monophosphate; Riboflavin-5-phosphate; UNII-7N464URE7E; Riboflavine 5'-phosphate; E101a; 7N464URE7E; CHEBI:17621; [(2R,3S,4S)-5-(7,8-dimethyl-2,4-dioxobenzo[g]pteridin-10-yl)-2,3,4-trihydroxypentyl] dihydrogen phosphate; 1-deoxy-1-(7,8-dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl)-5-O-phosphono-D-ribitol; Riboflavine 5'-(dihydrogen phosphate); BRN 0068086; {[(2R,3S,4S)-5-{7,8-dimethyl-2,4-dioxo-2H,3H,4H,10H-benzo[g]pteridin-10-yl}-2,3,4-trihydroxypentyl]oxy}phosphonic acid; Riboflavine-5'-phosphate; Bisulase; 1akq; 1akr; 1akt; 1akw; 1azl; 1czk; 1czl; 1czr; 1flm; 1nox; Flavinmononucleotid; Riboflavin, 5'-(dihydrogenphosphate)-; EINECS 205-664-7; 1c7f; Alloxazine mononucleotide; riboflavin-5'-monophosphate; Riboflavin-5'-phosphate na; SCHEMBL41133; riboflavin-5-phosphate-sodium; 4-26-00-02554 (Beilstein Handbook Reference); Riboflavin 5''''-Phosphate; GTPL5185; CHEMBL1201794; DTXSID8023559; Riboflavine 5-phosphate (6CI); SCHEMBL21544837; HY-B0964A; RIBOFLAVIN 5''-PHOSPHATE; ZINC3831425; BDBM50421345; Vitamin B2 (riboflavin-5-phosphate); DB03247; CS-0013780; C00061; Riboflavine phosphate (Riboflavine 5'-phosphate); Q376061; Riboflavin 5'-(dihydrogen phosphate) (8CI,9CI); Benzo[g]pteridine, riboflavin 5'-(dihydrogen phosphate) deriv.; D-ribitol, 1-deoxy-1-(3,4-dihydro-7,8-dimethyl-2,4-dioxobenzo[g]pteridin-10(2H)-yl)-, 5-(dihydrogen phosphate)

Activity data

No relevant experimental diagram

 Interaction ID 649
Target type Molecule
Target unique ID 643976
Activity N/A
Binding Conditions/Buffer

50 mM Tris-HCl, pH 7.5, 20 mM MgCl2
Assay

N/A
PubMed ID 11283591
Similar aptamers
Aptamer ID Aptamer chemistry Sequence Similarity
Apta_561 RNA GGAUAAUAGCCGUAGGUUGCGAAAGCGACCCUGAUGAGCCUGUGGAAACAGACGUGGCACAUGACUACGUCGAAACGGUAGCGAGAGCUC
84.44%
Apta_562 RNA GGAUAAUAGCCGUAGGUUGCGAAAGCGACCCUGAUGAGCCUUUAGGGCCAAGUGUGGUGAAAGACACACUCGAAACGGUAGCGAGAGCUC
84.44%
Apta_566 RNA GGAUAAUAGCCGUAGGUUGCGAAAGCGACCCUGAUGAGCCCUGCGAUGCAGAAAGGUGCUGACGACACAUCGAAACGGUAGCGAGAGCUC
84.44%
Apta_710 RNA GGAUAAUAGCCGUAGGUUGCGAAAGCGACCCUGAUGAGUCUGGAUACCAUGCAUGAUGCACCUUGGCAGUCUUACGAAACGGUAGCGAGAGCUC
84.04%
Apta_563 RNA GGAUAAUAGCCGUAGGUUGCGAAAGCGACCCUGAUGAGAAAGCCAAAGCCGUAGCGCAGAUGAUCUCGCCAUCAGUACCGAAACGGUAGCGAGAGCUC 77.55%
Apta_874 RNA GGAUAAUAGCCGUAGGUUGCGAAAGCGACCCUGAUGAGCCUUAGGAUAUGUCUGGAUACCAUGCAUGAUGCACCUUGGCAGUCUUACAGAAGGACGUCGAAACGGUAGCGAGAGCUC 75.21%
Apta_559 RNA GGAUGUCCAGUCGCUUGCAAUGCCCUUUUAGACCCUGAUGAGGAUCAUCGGACUUUGUCCUGUGGAGUAAGAUCGCGAAACGGUGAAAGCCGUAGGUCU 60.61%
Apta_612 RNA GGGCGACCCUGAUGAGCCUUAGGAUAUGCUUCGGCAGAAGGACGUCGAAACGGUGAAAGCCGUAGGUUGCCC 60.23%
Apta_551 RNA GGAUGUCCAGUCGCUUGCAAUGCCCUUUUAGACCCUGAUGAGCGGUGCUAGUUAGUUGCAGUUUCGGUUGUUACGCGAAACGGUGAAAGCCGUAGGUCU 58.59%
Apta_576 RNA GGCACCAAAGCUGAAGUAGCGGGAUAACUCAAAUUACUUUAGGUGUAUGAAGGUGAAACUAGCAAUGAA 54.55%
Apta_123 RNA GGGAGAAAGGGAAGCUUGAGCAGCAGGAGGGCCGGCGUUAGGGUUAGCGAGCCGAUUGAAAGAAGAAGGAACGAGCGUACGGAUCCGAUC 54.44%
Apta_38 RNA GGUAGAUACGAUGGAUACCCCCUGUGGCCCGUCAACACAGGGGAAGUGGCAUGACGCGCAGCCA 53.41%
Apta_305 RNA GGGAGGACGAUGCGGAUCGCCCUGAACCGGCCCAGCAGACUGCUGACGGCACGAUCCGCAUCGUCCUCCC 53.41%
Apta_416 RNA GGACCUCGGCGAAAGCCGGUAACGCCACAAGUCGGAGGGUAAGAUCUGACAGGAACUGGGUGACGGAGGUUAGGUGC 53.41%
Apta_1168 RNA GCGACUACGGUGAGGGUCGGGUCCAGUAGCUUCGGCUACUGUUGAGUAGAGUGUGGGCUCCGUAGUCGC 53.41%
Apta_816 RNA GGGUUCACUGCAGACUUGACGAAGCUUGAGAGAUGCCCCCUGAUGUGCAUUCUUGUUGUGUUGCGGCAAUGGAUCCACAUCUACGAAUUC 53.33%
Apta_280 RNA GAUAAUACGACUCACUAUAGGGUUCACUGCAGACUUGACGAAGCUUGCAGAAAAGGGGGAAGAAGAGGGUGAUUCAGGCGAGAGAAUGGAUCCACAUCUACGAAUUC 53.27%
Apta_719 RNA GGAAUGGAUCCACAUCUACGAAGGCUUUGAAGGUGAGACCGUGCAAAUGAGGAUGGUGUGGAUGAUUAGGGUUGUCGGUUUUCACUGCAGACUUGACGAAGCUU 52.88%
Apta_299 RNA AUACCAGCUUAUUCAAUUGCCUGAAGACUGGAUAUACUCUUAAGCAUUUCUAUAAUCGAGAUAGUAAGUGCAAUCU 52.27%
Apta_314 RNA GGUUACCAGCCUUCACUGCUCCCGGACGCGUCUGUAUCCGCUACCCGCCGCACCACGGUCGGUCACAC 52.27%

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AptaDB is an online database we developed to integrate comprehensive information about aptamer.
The detail of this database is described here:

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