Aptamer-target interaction descriptor
Aptamer-target interaction information
Interaction ID: 461
Aptamer sequence: AGCTCCAGAAGATAAATTACAGGTGGGTGGGTGGGCGGTGGAATTTAGCGGCGGAGCTCTGTGTGTGTTAGGGCAACTAGGATACTATGACCCC
Target unique ID: Q27102
Aptamer ID Aptamer descriptor Target chemistry Target name Affinity Binding Conditions/Buffer PubMed ID
Apta_456 AP65_A3 Protein Q27102_TRIVA 283 nM PBS-Tween 29972299
Structure information of aptamer
Aptamer Sequence: AGCTCCAGAAGATAAATTACAGGTGGGTGGGTGGGCGGTGGAATTTAGCGGCGGAGCTCTGTGTGTGTTAGGGCAACTAGGATACTATGACCCC
The optimal secondary structure in dot-bracket notation: ((((((......(((((..((.....((......))..))..))))).....))))))....((((.((((.....)))).)))).........
The centroid secondary structure in dot-bracket notation: .(((((..............................................))))).....((((.((((.....)))).)))).........
The MFE structure
The Centroid structure
The mountain plot representation
Aptamer information
Type Detail Type Detail
Aptamer ID Apta_456 Description AP65_A3
Aptamer chemistry DNA Length 94 nt
GC content 53.2% Molecular weight 29,340.75 Da
Molarity of 1 μg/μl solution 34.08 μM Number of G-quadruplexes 2
G-Score 21 Function Aptasensor
Sequence AGCTCCAGAAGATAAATTACAGGTGGGTGGGTGGGCGGTGGAATTTAGCGGCGGAGCTCTGTGTGTGTTAGGGCAACTAGGATACTATGACCCC
Applications Diagnostic assays for the reliable and rapid detection of T. vaginalis in vaginal swabs
Target information
Type Detail Type Detail
Uniprot ID Q27102 Protein name AP65-3 adhesin
Gene name(s) N/A Organism AP65-3 adhesin
Status unreviewed in uniprot database Length 567
Mass 63,134 Activity regulation N/A
Involvement in disease N/A Catalytic activity N/A
PDB ID(s)
N/A
Function N/A
Activity data
Interaction ID 461
Target type Protein
Target unique ID Q27102
Activity 283 nM
Binding Conditions/Buffer

PBS-Tween
Assay

Affinity dissociation constants KD of the full length aptamer candidates calculated by SPR (ii)
PubMed ID 29972299
Similar aptamers
Aptamer ID Aptamer chemistry Sequence Similarity
Apta_454 DNA AGCTCCAGAAGATAAATTACAGGTGAGGGCGGGCGGGTGGTTGTAATATGATCGAATGGTATATGTGTGTTTGCAACTAGGATACTATGACCCCG 77.89%
Apta_459 DNA AGCTCCAGAAGATAAATTACAGGGGCGGGGGGGCGGGGGAGGCGGAAGGCCTGCTAAAGTCGTTGTGAGCGAACCAACTAGGATACTATGACCCC 73.68%
Apta_455 DNA AGCTCCAGAAGATAAATTACAGGGGCCGGGGTGGCTCAGGCAAGGGGTTGACCTGTCGTAGGGATTGTTTTAACAACTAGGATACTATGACCCC 72.34%
Apta_457 DNA AGCTCCAGAAGATAAATTACAGGGGATCAGTAAGGTTGAGACGGCCTGAATCTATCGTGGAGACCACGCGACGCAACTAGGATACTATGACCCC 69.15%
Apta_458 DNA AGCTCCAGAAGATAAATTACAGGGAGAGTAAACTTTGCAAACACAACAATACCATTCCGGAACGTTCTTAACACAACTAGGATACTATGACCCC 64.89%
Apta_584 DNA GTACCAGCTTATTCAATTACACGGACAGAGGGTAGCGGCTCTGCGCATTGAGTTGCTGCGGGCTGAAGCGCGGTACATGGGAGATAGTATGTTCATCAG 54.55%
Apta_772 DNA GAATTCAGTCGGACAGCGCGGTGTTGGTGGTGGGGTGGTTTGGGAATCTGTTCGGCTGGAGATGGACGAATATCGTCTCCC 54.26%
Apta_775 DNA GAATTCAGTCGGACAGCGCGGTGTTGGTGGCGGGGGTGGTTGGGGGATTTGGCTGTCCTGAGTGATGGACGAATATCGTCTCCC 54.26%
Apta_1099 DNA ATCCATTGCCACTGACTACCAGCCGGGTGGGTGGGGGGGTTTGCTGGTATCGCATTGTGCGAAGTCAGTCGGTCGTTAGT 54.26%
Apta_265 DNA CCACTGCGGGGGTCTATACGTGAGGAAGAAGTGGGCAGGTCGCAGGTCGGAGGGAAAAGTTATCAGGCTGGATGGTAGCTCGGTCGGGGTGGGTGGGTTGGCAAGTCTGATTAGTTTTGGAGTACTCGCTCC 53.79%
Apta_887 DNA ACGCTCGGATGCCACTACAGGGGGGTGGTCCTGAGGGTGGTGTGGTTGGTTTGGTTTCCTCATGGACGTGCTGGTGAC 53.19%
Apta_1011 DNA GCTGTGTGACTCCTGCAATGGTAGCGGGTAGGGGAGGGAGGGTGAATGGAGGATGTTCATGGCAGCTGTATCTTGTCTCC 53.19%
Apta_1088 DNA ATCCAGAGTGACGCAGCATCGAGTGGCTTGTTTGTAATGTAGGGTTCCGGTCGTGGGTTGGACACGGTGGCTTAGT 53.19%
Apta_626 DNA ATACCAGCTTATTCAATTGGTGGTAGGATGGGCTCGATCGAGGTCTTCAGTCGGCTCGGTTTAGTTTATGTTCTCCTGTAGATAGTAAGTGCAATCT 52.58%
Apta_626 DNA ATACCAGCTTATTCAATTGGTGGTAGGATGGGCTCGATCGAGGTCTTCAGTCGGCTCGGTTTAGTTTATGTTCTCCTGTAGATAGTAAGTGCAATCT 52.58%
Apta_78 DNA ATCTCGACTAGTCATAGGGGGCGCGAACATACGCGGTTGGTGTGGTTGGCTGACAATACTCGT 52.13%
Apta_99 DNA AGCAGCACAGAGGTCAGATGTCGGGCGGTTCGGGACCTTGCTGCGACATATGCGTATTATCCTATGCGTGCTACCGTGAA 52.13%
Apta_99 DNA AGCAGCACAGAGGTCAGATGTCGGGCGGTTCGGGACCTTGCTGCGACATATGCGTATTATCCTATGCGTGCTACCGTGAA 52.13%
Apta_151 DNA GCAATGGTACGGTACTTCCGCGGTCCGGGGTGGGTGGGTGGTGGGGGGTGCGGGGGGGCGGCCGCAAAAGTGCACGCTACTTTGCTAA 52.13%
Apta_450 DNA ATACCAGCTTATTCAATTACATGTCCTGAAGGGGAATAATATACAGCTTTGGGTGGGTAGATAGTAAGTGCAATCT 52.13%

ABOUT

AptaDB is an online database we developed to integrate comprehensive information about aptamer.
The detail of this database is described here:

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