Aptamer-target interaction descriptor
Aptamer-target interaction information
| Aptamer ID | Aptamer descriptor | Target chemistry | Target name | Affinity | Binding Conditions/Buffer | PubMed ID |
|---|---|---|---|---|---|---|
| Apta_1208 | Aptamer 10 | Cell | Mycobacterium tuberculosis subsp. Tuberculosis | 110 nM | 20 mmol/L HEPES buffer at pH 7.35, 1 mmol/L MgCl2, 120 mmol/L NaCl, 1 mmol/L CaCl2, and 5 mmol/L KCl | 28689112 |
Structure information of aptamer
| Aptamer Sequence: | CCCTGCGGGGCTGCCCGATATGTGTCCAGGTGGTG |
| The optimal secondary structure in dot-bracket notation: | .((((((((....)))).........))))..... |
| The centroid secondary structure in dot-bracket notation: | ..........(((((.(((....)))..))))).. |
The MFE structure
The Centroid structure
The mountain plot representation
Aptamer information
| Type | Detail | Type | Detail |
|---|---|---|---|
| Aptamer ID | Apta_1208 | Description | Aptamer 10 |
| Aptamer chemistry | DNA | Length | 35 nt |
| GC content | 68.6% | Molecular weight | 10,811.90 Da |
| Molarity of 1 μg/μl solution | 92.49 μM | Number of G-quadruplexes | No QGRS found |
| G-Score | N/A | Function | Target detection |
| Sequence | CCCTGCGGGGCTGCCCGATATGTGTCCAGGTGGTG | ||
| Applications | Detection of H37Rv in clinical diagnosis | ||
Target information
| Type | Detail | Type | Detail |
|---|---|---|---|
| ATCC ID | 27294 | Cell name | Mycobacterium tuberculosis subsp. Tuberculosis |
| Category | Bacteria | Organism | N/A |
| Product type | N/A | Cell type | N/A |
| Morphology | N/A | Tissue | N/A |
| Disease | N/A | Product format | Frozen |
| Antigen expression | N/A | Genes expressed | N/A |
| Cell description | This strain has been assigned to Risk Group 3-agents associated with serious or lethal human disease for which preventive or therapeutic interventions may be available. |
|
|
| Application(s) | N/A | ||
Activity data
|
No relevant experimental diagram |
Interaction ID | 1270 |
| Target type | Cell | |
| Target unique ID | 27294 | |
| Activity | 110 nM | |
| Binding Conditions/Buffer | 20 mmol/L HEPES buffer at pH 7.35, 1 mmol/L MgCl2, 120 mmol/L NaCl, 1 mmol/L CaCl2, and 5 mmol/L KCl |
|
| Assay | N/A |
|
| PubMed ID | 28689112 |
Similar aptamers
| Aptamer ID | Aptamer chemistry | Sequence | Similarity |
|---|---|---|---|
| Apta_1199 | DNA | CCCTGCGGGGCTGCCCGATATGTGTCCAAGTGGTG | |
| Apta_1199 | DNA | CCCTGCGGGGCTGCCCGATATGTGTCCAAGTGGTG | |
| Apta_1199 | DNA | CCCTGCGGGGCTGCCCGATATGTGTCCAAGTGGTG | |
| Apta_1199 | DNA | CCCTGCGGGGCTGCCCGATATGTGTCCAAGTGGTG | |
| Apta_1203 | DNA | CCCTGCGGGGCTACCCGATATGTGTCCGAGTGGTG | |
| Apta_692 | DNA | ACGTTGACGCTGGTGCCCGCTTGTGGTGCGAGTGTTGTGT | |
| Apta_57 | DNA | GCGGGTCGGTTGCTCGCTTCGCCCGATCGGTCTAAGGGTG | |
| Apta_691 | DNA | CGACGCGCGTTGGTGGTGGATGGTGTGTTACACGTGTTGT | |
| Apta_250 | DNA | CCCTGGCCGCCCTCTGGCGCGCTGATGT | |
| Apta_1040 | DNA | CAATTGGGCCCGTCCGTATGGTGGGT | |
| Apta_340 | DNA | TACTCAGGGCACTGCAAGCAATTGTGGTCCCAATGGGCTGAGTA | |
| Apta_829 | DNA | CCCTCCGGGGGGGTCATCGGGATACCTGGTAAGGATA | |
| Apta_1059 | DNA | TCGTGACGCCGTGCAGTTACCGATACGAGCCTCGTTTTG | |
| Apta_552 | DNA | CACCTGGGGGAGTATTGCGGAGGAAGGTTCCAGGTG | |
| Apta_722 | DNA | CTCTCGGGACGACGGCCCGATCTCAGAGTAGTCGTCCC | |
| Apta_148 | DNA | CCGTAGGTTCGGGGTCGGAGTGGTCCGGAAGGTGGCGTGG | |
| Apta_873 | DNA | CCACCGAGCCTACCACATGTGACATCCCAGGACATAGCTG | |
| Apta_1262 | DNA | ACAAGGGGTGCAGGGGTCCGCGATTGTGACTGTGTGTGCG | |
| Apta_144 | DNA | GGTGCGGTTCGTGCGGTTGTAGTACTCGTGGCCGATAGAGGTAG | |
| Apta_24 | DNA | TGTGGGGATGGATGGGCCGGGCTGC |
DEV TOOL
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