Aptamer-target interaction descriptor
Aptamer-target interaction information
Interaction ID: 1116
Aptamer sequence: AACTTATCGGAGCGTGATTTCCGTCTCGCCGCTTTCCTTT
Target unique ID: Other-53
| Aptamer ID | Aptamer descriptor | Target chemistry | Target name | Affinity | Binding Conditions/Buffer | PubMed ID |
|---|---|---|---|---|---|---|
| Apta_1063 | Apt_NDV02 | Other | Newcastle disease virus (NDV) | 85.1 nM | PBS (pH 7.2) with 150 mM NaCl and 5 mM MgCl2 | 32790805 |
Structure information of aptamer
| Aptamer Sequence: | AACTTATCGGAGCGTGATTTCCGTCTCGCCGCTTTCCTTT |
| The optimal secondary structure in dot-bracket notation: | ........(((((((((........))).))))))..... |
| The centroid secondary structure in dot-bracket notation: | ..........(((.(((........)))..)))....... |
The MFE structure
The Centroid structure
The mountain plot representation
Aptamer information
| Type | Detail | Type | Detail |
|---|---|---|---|
| Aptamer ID | Apta_1063 | Description | Apt_NDV02 |
| Aptamer chemistry | DNA | Length | 40 nt |
| GC content | 50.0% | Molecular weight | 12,170.80 Da |
| Molarity of 1 μg/μl solution | 82.16 μM | Number of G-quadruplexes | No QGRS found |
| G-Score | N/A | Function | Target detection |
| Sequence | AACTTATCGGAGCGTGATTTCCGTCTCGCCGCTTTCCTTT | ||
| Applications | Detection of NDV in poultry samples | ||
Target information
| Type | Detail | Type | Detail |
|---|---|---|---|
| Target ID | Other-53 | Name | Newcastle disease virus (NDV) |
Activity data
 |
Interaction ID | 1116 |
| Target type | Other | |
| Target unique ID | Other-53 | |
| Activity | 85.1 nM | |
| Binding Conditions/Buffer | PBS (pH 7.2) with 150 mM NaCl and 5 mM MgCl2 |
|
| Assay | Highly specific aptamers against NDV |
|
| PubMed ID | 32790805 |
Similar aptamers
| Aptamer ID | Aptamer chemistry | Sequence | Similarity |
|---|---|---|---|
| Apta_434 | DNA | ACACGACGGGAATACTGACTCTCCCCCATGT | |
| Apta_1066 | DNA | CCTACGTTGGAGTGGGGTTTGCGCAGGCCGTTCTTTCCAA | |
| Apta_979 | DNA | ATGAGTAGTGCGGAGGGATGTGAATACTGACGCGGTCATAGTCGCTGTTGTACCATTGA | |
| Apta_290 | DNA | GAACTCACCGGGAAGAAGCCCGTTCCGTCACAGACATGTT | |
| Apta_852 | DNA | CATCTGTGTGAAGACTATATGGCGCTCACATATTTCTTTC | |
| Apta_556 | DNA | GGCTCTCGGGACGACATGGATTTTCCATCAACGAAGTGCGTCCGTCCC | |
| Apta_614 | DNA | AATCGCATTACCTTATACCAGCTTATTCAATTACGTCTGCACATACCAGCTTATTCAATT | |
| Apta_1012 | DNA | CACATTAGGGCGGGGTACTCCTATCACGTATGGGGGCCTGT | |
| Apta_821 | DNA | CACAGTCACTCAGACGGCCGCTATTGTTGCCAGATTGCCTTTGGC | |
| Apta_1156 | DNA | TTCTGGTGTGGTAACTCATGTATCGGTCGTGGGGGTCGTGGCATT | |
| Apta_571 | DNA | ACCTGCGATAGGTAGTTTGTTTCTGTTGCCCTAGCGTCCGTCGTAACAAGTCA | |
| Apta_910 | DNA | TCACGTGCATGATAGACGGCGAAGCCGTCGAGTTGCTGTGTGCCGATGCACGTGA | |
| Apta_357 | DNA | ACAATGTCGCTCTCCGCCGCAGGAGCATTGTCTGTCTTTATGCTTCTCTTTTTTGTTGC | |
| Apta_183 | DNA | TAGCACTGTGCGGCGCGTATTGTTCTAATCTGATTACATT | |
| Apta_205 | DNA | TTAAGGCTTTAGGTCTGAGATCTCTT | |
| Apta_291 | DNA | AAAAATCTAGGCGCTGAAGCCCCGCTTCCTTACCTTCAC | |
| Apta_395 | DNA | AATCCACGTATCGACTAGCTCAAACCAGCCTGATAGAGCCATTCGCTTTA | |
| Apta_498 | DNA | GAACTCATTGGCTGGAGGCGGCAGTACCGCTTGAGTT | |
| Apta_604 | DNA | TCCTGACCTTAGCCTATGTTTTCTCTACCGGCTATGTTAC | |
| Apta_675 | DNA | ACTGTCCGTCGGGTTTAGGGTGGCGTTCGG |
DEV TOOL
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