Aptamer-target interaction descriptor
Aptamer-target interaction information
Interaction ID: 1066
Aptamer sequence: ATGGGAACAGAGCGGCGCAGAGACCCAATGCCACGAGTACCTGACCCTATCAACCCGTGA
Target unique ID: Other-42
| Aptamer ID | Aptamer descriptor | Target chemistry | Target name | Affinity | Binding Conditions/Buffer | PubMed ID |
|---|---|---|---|---|---|---|
| Apta_983 | BC2 | Other | beta-crosslap (BC) | 59.34 nM | 2 mM MgCl2, 50 mM Tris (pH 7.5) and 150 mM NaCl in distilled water | 33379043 |
Structure information of aptamer
| Aptamer Sequence: | ATGGGAACAGAGCGGCGCAGAGACCCAATGCCACGAGTACCTGACCCTATCAACCCGTGA |
| The optimal secondary structure in dot-bracket notation: | (((((....((..((..(((..((............))..)))..))..))..))))).. |
| The centroid secondary structure in dot-bracket notation: | (((((............(((..((............))..)))..........))))).. |
The MFE structure
The Centroid structure
The mountain plot representation
Aptamer information
| Type | Detail | Type | Detail |
|---|---|---|---|
| Aptamer ID | Apta_983 | Description | BC2 |
| Aptamer chemistry | DNA | Length | 60 nt |
| GC content | 58.3% | Molecular weight | 18,466.86 Da |
| Molarity of 1 μg/μl solution | 54.15 μM | Number of G-quadruplexes | No QGRS found |
| G-Score | N/A | Function | Aptasensor |
| Sequence | ATGGGAACAGAGCGGCGCAGAGACCCAATGCCACGAGTACCTGACCCTATCAACCCGTGA | ||
| Applications | Binding to target proteins | ||
Target information
| Type | Detail | Type | Detail |
|---|---|---|---|
| Target ID | Other-42 | Name | beta-crosslap (BC) |
Activity data
 |
Interaction ID | 1066 |
| Target type | Other | |
| Target unique ID | Other-42 | |
| Activity | 59.34 nM | |
| Binding Conditions/Buffer | 2 mM MgCl2, 50 mM Tris (pH 7.5) and 150 mM NaCl in distilled water |
|
| Assay | Determination of affinity/dissociation constant (Kd) of from the saturation binding curve |
|
| PubMed ID | 33379043 |
Similar aptamers
| Aptamer ID | Aptamer chemistry | Sequence | Similarity |
|---|---|---|---|
| Apta_106 | DNA | AGCAGCACAGAGGTCAGATGGAGCCAGGAGTCGGCCTACAGAAGATTCTGATGTACCTCACCTATGCGTGCTACCGTGAA | |
| Apta_108 | DNA | AGCAGCACAGAGGTCAGATGCTTTGCCACGGCAACGTCCCAAAACTAATGGTAACTATACCCTATGCGTGCTACCGTGAA | |
| Apta_106 | DNA | AGCAGCACAGAGGTCAGATGGAGCCAGGAGTCGGCCTACAGAAGATTCTGATGTACCTCACCTATGCGTGCTACCGTGAA | |
| Apta_108 | DNA | AGCAGCACAGAGGTCAGATGCTTTGCCACGGCAACGTCCCAAAACTAATGGTAACTATACCCTATGCGTGCTACCGTGAA | |
| Apta_173 | DNA | AGCAGCACAGAGGTCAGATGGCAGGTTTCGACGTACAATGCTATGGAGGCTTTATGATCGCCTATGCGTGCTACCGTGAA | |
| Apta_177 | DNA | AGCAGCACAGAGGTCAGATGCCATAGGTGCCTGAATTGTCCCAAACATTCGCATGATCGACCTATGCGTGCTACCGTGAA | |
| Apta_232 | DNA | AGCAGCACAGAGGTCAGATGCTATGAGCAGATCCGATAGAAAGTTAATGCCCTAGAACATCCTATGCGTGCTACCGTGAA | |
| Apta_685 | DNA | GGGGCAACAAACACGGAAGAAAATGAATCTACATACGTGGACATATATCCTGCCGCGTG | |
| Apta_698 | DNA | AGCAGCACAGAGGTCAGATGCACTCGGACCCCATTCTCCTTCCATCCCTCATCCGTCCACCCTATGCGTGCTACCGTGAA | |
| Apta_1046 | DNA | TCGCATGGAGGGCAGAGCCGCCTGCCGGGATCCGGCCCTCTTGGGCGGGC | |
| Apta_1219 | DNA | GCGCAGAACCGACAGCAAAACGGAAGTCCACCACGACTATTGGTGCCCAATCTACCGTA | |
| Apta_996 | DNA | ATAGGAGTCGACCGACCAGACAACCCTACGCGACCAACCAGATGACCTACGTGCGTCTACATCTAGACTC | |
| Apta_989 | DNA | ATGCGGGTACATCTCTCCAACCAGTCAAACTGCTATGATAAGACCTCATTCAACCCCGGTA | |
| Apta_1233 | DNA | TCACGAGAGAGCGAGAGCGCCCCCCCACCACAGCCGTCACCACCCTATTCCTCTGCCGTTG | |
| Apta_228 | DNA | AGCAGCACAGAGGTCAGATGCGGCGCGGGGTCTTTTACAAATAGTTGTCCTAGCCACGCCTATGCGTGCTACCGTGAA | |
| Apta_103 | DNA | AGCAGCACAGAGGTCAGATGCATCGCATTATTCGCGGCCGGCCAACGAGAGTATGTTTCTCCTATGCGTGCTACCGTGAA | |
| Apta_104 | DNA | AGCAGCACAGAGGTCAGATGCAAACCACAGCCTGAGTGGTTAGCGTATGTCATTTACGGACCTATGCGTGCTACCGTGAA | |
| Apta_104 | DNA | AGCAGCACAGAGGTCAGATGCAAACCACAGCCTGAGTGGTTAGCGTATGTCATTTACGGACCTATGCGTGCTACCGTGAA | |
| Apta_103 | DNA | AGCAGCACAGAGGTCAGATGCATCGCATTATTCGCGGCCGGCCAACGAGAGTATGTTTCTCCTATGCGTGCTACCGTGAA | |
| Apta_175 | DNA | AGCAGCACAGAGGTCAGATGAGGACTGTCGATAAGTATAATGGCAAGTAGCTCGATACATCCTATGCGTGCTACCGTGAA |
DEV TOOL
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