Aptamer-target interaction descriptor
Aptamer-target interaction information
Interaction ID: 1056
Aptamer sequence: TATGTAATGTTGACGTAATTTATCTCTGTGAGAATAAGCAGGTGGTATCC
Target unique ID: Other-41
| Aptamer ID | Aptamer descriptor | Target chemistry | Target name | Affinity | Binding Conditions/Buffer | PubMed ID |
|---|---|---|---|---|---|---|
| Apta_973 | H3.1 | Other | HIV reverse transcriptase (HIV RT) | 34.5 nM | 20 mM Tris-HCl [pH 7.4], 140 mM NaCl, 5 mM KCl, 1 mM MgCl2, and 1 mM CaCl2 | 32298104 |
Structure information of aptamer
| Aptamer Sequence: | TATGTAATGTTGACGTAATTTATCTCTGTGAGAATAAGCAGGTGGTATCC |
| The optimal secondary structure in dot-bracket notation: | (((((.......)))))...(((((((((........))))).))))... |
| The centroid secondary structure in dot-bracket notation: | (((((.......)))))...(((((((((........))))).))))... |
The MFE structure
The Centroid structure
The mountain plot representation
Aptamer information
| Type | Detail | Type | Detail |
|---|---|---|---|
| Aptamer ID | Apta_973 | Description | H3.1 |
| Aptamer chemistry | DNA | Length | 50 nt |
| GC content | 36.0% | Molecular weight | 15,483.97 Da |
| Molarity of 1 μg/μl solution | 64.58 μM | Number of G-quadruplexes | No QGRS found |
| G-Score | N/A | Function | Target recognition |
| Sequence | TATGTAATGTTGACGTAATTTATCTCTGTGAGAATAAGCAGGTGGTATCC | ||
| Applications | Binding to target proteins | ||
Target information
| Type | Detail | Type | Detail |
|---|---|---|---|
| Target ID | Other-41 | Name | HIV reverse transcriptase (HIV RT) |
Activity data
|
No relevant experimental diagram |
Interaction ID | 1056 |
| Target type | Other | |
| Target unique ID | Other-41 | |
| Activity | 34.5 nM | |
| Binding Conditions/Buffer | 20 mM Tris-HCl [pH 7.4], 140 mM NaCl, 5 mM KCl, 1 mM MgCl2, and 1 mM CaCl2 |
|
| Assay | N/A |
|
| PubMed ID | 32298104 |
Similar aptamers
| Aptamer ID | Aptamer chemistry | Sequence | Similarity |
|---|---|---|---|
| Apta_976 | DNA | GATGAATATCGCAATGAAATTATATATGTATAATTGGAACGGTGGTATCC | |
| Apta_970 | DNA | TTATGTAGCATTTATGAAATTTTTAAATCAATTTACTATTGGTGGTATCC | |
| Apta_972 | DNA | TGACAGTACGTACTGAACTAATTTATAAGTAATTTGCTATGGTGGTATCC | |
| Apta_971 | DNA | TAGTCTAGGAACGGTACGATCGTATTCCAAGGACTTTGCTGGTGGTATCC | |
| Apta_912 | DNA | TAGTATGGACTTGTCTTCTTGTCAGAGTCTGGCAGCACGT | |
| Apta_974 | DNA | CATGGTGTCAATACTATACCTTTTGCCGATGGTAACAGTTGGTGGTATCC | |
| Apta_470 | DNA | CTGTAATTGGCGTATGTAACCCAGGCACCAAACACCTCAT | |
| Apta_646 | DNA | TGGAGCTTGGATTGATGTGGTGTGTGAGTGCGGTGCCC | |
| Apta_947 | DNA | CATGGCTAGGTGTTTATTAATCCTGTAGGATTTGCGGAAT | |
| Apta_975 | DNA | AGACATAGTACATAACCGATCAATGAACATTTAATTAAATGGTGGTATCC | |
| Apta_987 | DNA | GTACTGTCAATTGGAAGTGGTGTTACGTTGTGTAGTCAAATCAGTGC | |
| Apta_991 | DNA | AGCAGTGAAGAGGCGAGAGATTTATGAGGGTAGCGTCCACATATGCCAGGATCGTGTTG | |
| Apta_884 | DNA | ATACCAGCTTATTCAATTTGCACCACTTATTGTTACTAATCTGAGATAGTAAGTGCAATCT | |
| Apta_58 | DNA | GCACCTTGATGACATGATAGTCGTTGTGTATGCAGTTGGC | |
| Apta_220 | DNA | ATCAACTCACCGTAGGTCTAGTGAGAACTTCAAGTCTACT | |
| Apta_302 | DNA | ATCCTGTGAGGAATGCTCATGCATAGCAAGGGCT | |
| Apta_441 | DNA | TGAATCTCGCGCTCGTTGGTACCCTTAAAATAAAGGCATA | |
| Apta_468 | DNA | CTGTAATTGGCGTATGTAACCCAGGCACCAAACACCCCAT | |
| Apta_597 | DNA | TACTGGGCTGGGCTTGGATTAGATCACAGTGGAACATACAGGACACACG | |
| Apta_733 | DNA | TAGGCAGTGGTTTGACGTCCGCATGTTGGGAATAGCCACGCCT |
DEV TOOL
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