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Primary-literature peptidemedium evidence

PEPDIA-PLP-003483

temporin-SHf

Aliases: temporin-SHf

Normalized sequence

FFFLSRIF

8 amino acids

Release PepDiana-V1-20260620

25

Activity records

1

Source papers

25

Positive

0

Negative / threshold

Cross-layer links

Related Integrated records

Versioned scientific descriptors

Physicochemical properties and standard representations

not calculated

Reported properties

No separate physicochemical property was reported in the primary-literature identity record. PepDiana release values are shown as computed properties.

Computed properties

physchem-20260620

Molecular weight

Not calculated

Molecular formula

Not calculated

Theoretical pI

Not calculated

Net charge at pH 7

Not calculated

GRAVY

Not calculated

Instability index

Not calculated

Aromaticity

Not calculated

Topological polar surface area

Not calculated

cLogP

Not calculated

Hydrogen-bond donors

Not calculated

Hydrogen-bond acceptors

Not calculated

Rotatable bonds

Not calculated

Method: Not recorded

Tool: Not recorded

Calculated: Not recorded

Sequence representations

representations-20260620

ProForma 2.0

Not calculated for this record

HELM 2.0

Not calculated for this record

Canonical SMILES

Not calculated for this record

Isomeric SMILES

Not calculated for this record

Paper-level observations

Experimental evidence grouped by activity

Anticancer 16 records

PMC10847208

16 observations
Antimicrobial 8 records

PMC10847208

8 observations
Toxicity 1 records

PMC10847208

1 observations
ToxicityHemolyticPositive observation
Record detail

The (HL50) 50% erythrolysis was only at 267.97 μM temporin-SHf concentration (Fig. 6). Temporin-SHf was non-hemolytic against human erythrocytes up to 120 μM.

Measure
HD50
Value
267.97 µM
Target
Homo sapiens
Assay
Not reported by source
Source publication

Citation and release provenance

Cite this identity as PepDiana record PEPDIA-PLP-003483, release PepDiana-V1-20260620. Experimental observations retain their paper, mention, and activity-record identifiers.

Record updated: 2026-06-22T07:14:26.229247+00:00