ProForma 2.0
Not calculated for this record
temporin-SHf
Aliases: temporin-SHf
Normalized sequence
FFFLSRIF
8 amino acids
Release PepDiana-V1-20260620
25
Activity records
1
Source papers
25
Positive
0
Negative / threshold
Cross-layer links
Versioned scientific descriptors
No separate physicochemical property was reported in the primary-literature identity record. PepDiana release values are shown as computed properties.
Molecular weight
Not calculated
Molecular formula
Not calculated
Theoretical pI
Not calculated
Net charge at pH 7
Not calculated
GRAVY
Not calculated
Instability index
Not calculated
Aromaticity
Not calculated
Topological polar surface area
Not calculated
cLogP
Not calculated
Hydrogen-bond donors
Not calculated
Hydrogen-bond acceptors
Not calculated
Rotatable bonds
Not calculated
Method: Not recorded
Tool: Not recorded
Calculated: Not recorded
ProForma 2.0
Not calculated for this record
HELM 2.0
Not calculated for this record
Canonical SMILES
Not calculated for this record
Isomeric SMILES
Not calculated for this record
Paper-level observations
Table 4: A549 IC50 6 h = 27.71 ± 1.150 μM
Table 4: A549 IC50 12 h = 26.27 ± 1.054 μM
Table 4: A549 IC50 24 h = 24.03 ± 0.945 μM
Table 4: A549 IC50 48 h = 21.85 ± 0.927 μM
Table 4: MCF-7 IC50 6 h = 35.77 ± 1.854 μM
Table 4: MCF-7 IC50 12 h = 34.45 ± 1.645 μM
Table 4: MCF-7 IC50 24 h = 32.76 ± 1.528 μM
Table 4: MCF-7 IC50 48 h = 30.79 ± 1.197 μM
Table 4: PC-3 IC50 6 h = 40.10 ± 0.721 μM
Table 4: PC-3 IC50 12 h = 38.62 ± 0.658 μM
Table 4: PC-3 IC50 24 h = 36.67 ± 0.729 μM
Table 4: PC-3 IC50 48 h = 35.05 ± 0.673 μM
Table 4: HepG2 IC50 6 h = 37.95 ± 1.111 μM
Table 4: HepG2 IC50 12 h = 35.31 ± 1.248 μM
Table 4: HepG2 IC50 24 h = 32.64 ± 1.350 μM
Table 4: HepG2 IC50 48 h = 30.32 ± 1.364 μM
Table 2: Escherichia coli (ATCC 25922) MIC 24.74 ± 0.968 μM
Table 2: Pseudomonas aeruginosa (ATCC 15442) MIC 108.32 ± 1.758 μM
Table 2: Klebsiella pneumonia (ATCC 13883) MIC 42.56 ± 1.455 μM
Table 2: Aeromonas hydrophila (ATCC 7966) MIC 167.35 ± 2.127 μM
Table 2: Staphylococcus aureus (MTCC 9542) MIC 34.07 ± 1.632 μM
Table 2: Bacillus subtilis (ATCC 6051) MIC 39.27 ± 1.359 μM
Table 3: Aspergillus niger MFC 429.10 ± 2.216 μM
Table 3: A. fumigatus MFC 488.89 ± 3.317 μM
The (HL50) 50% erythrolysis was only at 267.97 μM temporin-SHf concentration (Fig. 6). Temporin-SHf was non-hemolytic against human erythrocytes up to 120 μM.
Citation and release provenance
Cite this identity as PepDiana record PEPDIA-PLP-003483, release PepDiana-V1-20260620. Experimental observations retain their paper, mention, and activity-record identifiers.
Record updated: 2026-06-22T07:14:26.229247+00:00