OtherAnti-HIVPositive observation
Record detail Figure 5A; Table S2. OT positive control on hOTR.
- Measure
- EC50
- Value
- Not reported
- Target
- Homo sapiens
- Assay
- Not reported by source
Primary literature evidence
Experimental evidence search
Search paper-level observations with their value, target, assay, evidence sentence, source location, and stable record links. Evidence without a safely standardized sequence remains visible without being misrepresented as a canonical peptide.
Evidence records
20 results
OtherAnti-HIVNegative / threshold
Record detail Figure 5A; Table S2. DCMAC-OT 1 on hOTR. Text: '150 → >3900-fold higher EC50 values than parent peptides'.
- Measure
- EC50
- Value
- >3,900
- Target
- Homo sapiens
- Assay
- Not reported by source
OtherAnti-HIVNegative / threshold
Record detail Figure 5A; Table S2. DCANBP-OT 3 on hOTR. Text: '>2,100-3,900-fold higher EC50 values compared to parent peptides'.
- Measure
- EC50
- Value
- >2,100
- Target
- Homo sapiens
- Assay
- Not reported by source
OtherAnti-HIVPositive observation
Record detail Figure 5A; Table S2. Me6I2-BODIPY-OT 5 on hOTR. Text: '3- to 9-fold rightward shift in EC50 compared to OT'.
- Measure
- EC50
- Value
- =5
- Target
- Homo sapiens
- Assay
- Not reported by source
OtherAnti-HIVPositive observation
Record detail Figure 5D; Table S3. DCMAC-OT 1* on hOTR. Text: '75-fold increase in potency for hOTR'.
- Measure
- EC50
- Value
- =1
- Target
- Homo sapiens
- Assay
- Not reported by source
OtherAnti-HIVPositive observation
Record detail Figure 5D; Table S3. DCANBP-OT 3* on hOTR. Text: '400-fold increase in activity'.
- Measure
- EC50
- Value
- =3
- Target
- Homo sapiens
- Assay
- Not reported by source
OtherAnti-HIVPositive observation
Record detail Figure 5D; Table S3. Me6I2-BODIPY-OT 5* on hOTR. Text: 'only a minor increase in activity (~2-fold)'.
- Measure
- EC50
- Value
- ~2
- Target
- Homo sapiens
- Assay
- Not reported by source
OtherAntibacterialNegative / threshold
Record detail Figure 5F. DCMAC-OT 1 at 100 nM on hV1aR. Text: 'most caged photoprobes exhibited no activity at 100 nM'.
- Measure
- percent_inhibition
- Value
- na
- Target
- Homo sapiens
- Assay
- Not reported by source
OtherAntibacterialNegative / threshold
Record detail Figure 5F. DCMAC-OT 1 at 100 nM on hV1bR. Text: 'most caged photoprobes exhibited no activity at 100 nM'.
- Measure
- percent_inhibition
- Value
- na
- Target
- Homo sapiens
- Assay
- Not reported by source
OtherAntibacterialNegative / threshold
Record detail Figure 5F. DCANBP-OT 3 at 100 nM on hV1aR. Text: 'most caged photoprobes exhibited no activity at 100 nM'.
- Measure
- percent_inhibition
- Value
- na
- Target
- Homo sapiens
- Assay
- Not reported by source
OtherAntibacterialNegative / threshold
Record detail Figure 5F. DCANBP-OT 3 at 100 nM on hV1bR. Text: 'most caged photoprobes exhibited no activity at 100 nM'.
- Measure
- percent_inhibition
- Value
- na
- Target
- Homo sapiens
- Assay
- Not reported by source
OtherAntibacterialNegative / threshold
Record detail Figure 5F. Me6I2-BODIPY-OT 5 at 100 nM on hV1aR. Text: 'most caged photoprobes exhibited no activity at 100 nM'.
- Measure
- percent_inhibition
- Value
- na
- Target
- Homo sapiens
- Assay
- Not reported by source
OtherAntibacterialNegative / threshold
Record detail Figure 5F. Me6I2-BODIPY-OT 5 at 100 nM on hV1bR. Text: 'most caged photoprobes exhibited no activity at 100 nM'.
- Measure
- percent_inhibition
- Value
- na
- Target
- Homo sapiens
- Assay
- Not reported by source
ToxicityCytotoxicPositive observation
Record detail Figure 4. OT positive control in MTT assay. Text: 'OT itself reduced cell viability over 48 h'.
- Measure
- cell_viability
- Value
- =4%
- Target
- Homo sapiens
- Assay
- Not reported by source
ToxicityCytotoxicPositive observation
Record detail Figure 4. DCMAC-OT 1 in MTT assay. Text: 'Most photocaged OT probes ... exhibited higher cell viability than unmodified OT'.
- Measure
- cell_viability
- Value
- =4%
- Target
- Homo sapiens
- Assay
- Not reported by source
ToxicityCytotoxicPositive observation
Record detail Figure 4. DCMAC-OT 1* in MTT assay. Text: 'The uncaged compound mixtures exhibited values comparable to those of OT'.
- Measure
- cell_viability
- Value
- =4%
- Target
- Homo sapiens
- Assay
- Not reported by source
ToxicityCytotoxicPositive observation
Record detail Figure 4. DCANBP-OT 3 in MTT assay. Text: 'Most photocaged OT probes ... exhibited higher cell viability than unmodified OT'.
- Measure
- cell_viability
- Value
- =4%
- Target
- Homo sapiens
- Assay
- Not reported by source
ToxicityCytotoxicPositive observation
Record detail Figure 4. DCANBP-OT 3* in MTT assay. Text: 'The uncaged compound mixtures exhibited values comparable to those of OT'.
- Measure
- cell_viability
- Value
- =4%
- Target
- Homo sapiens
- Assay
- Not reported by source
ToxicityCytotoxicPositive observation
Record detail Figure 4. Me6I2-BODIPY-OT 5 in MTT assay. Text: 'except for 1 uM 5' exhibited higher cell viability than unmodified OT.
- Measure
- cell_viability
- Value
- =4%
- Target
- Homo sapiens
- Assay
- Not reported by source
ToxicityCytotoxicPositive observation
Record detail Figure 4. Me6I2-BODIPY-OT 5* in MTT assay. Text: 'The uncaged compound mixtures exhibited values comparable to those of OT'.
- Measure
- cell_viability
- Value
- =4%
- Target
- Homo sapiens
- Assay
- Not reported by source
Names such as P1, PEP1, or peptide 1 are paper-local labels. Search results group them by publication and never assume cross-paper molecular identity without sequence or explicit structural evidence.